Interaction of Tritrichomonas foetus and the bovine oviduct in an organ culture model

Benchimol, Marlene; Dias, Angelo Burla; Fontes, Reginaldo da Silva

doi:10.1016/j.vetpar.2006.04.011

Cited by 5 publications

(4 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Singh et al showed that T. foetus induces apoptosis of bovine vaginal (Singh et al, 2004) and uterine epithelial cells (Singh et al, 2005) by the action of a cysteine-protease known as CP30. In addition, it has been shown that T. foetus induces the apoptosis of bovine oviductal epithelial cells (Benchimol et al, 2006;Midlej et al, 2009) and oocytes in vitro (Benchimol et al, 2007). These results are just some examples that support the apoptosis as a critical process on the pathogenesis of bovine tritrichomonosis.…”

Section: Discussionmentioning

confidence: 80%

Apoptosis and cell proliferation in the mouse model of embryonic death induced by Tritrichomonas foetus infection

Woudwyk

Zanuzzi

Nishida

et al. 2015

Experimental Parasitology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 80%

Apoptosis and cell proliferation in the mouse model of embryonic death induced by Tritrichomonas foetus infection

Woudwyk

Zanuzzi

Nishida

et al. 2015

Experimental Parasitology

View full text Add to dashboard Cite

“…It has been reported that the gold standard for diagnosing T. foetus consists of culturing the live microorganism from smegma or cervicouterine mucus. However, in studies in which samples from the vaginal mucosa or from uterine lavage were used, these were not used to make a diagnosis but to evaluate adhesion to the vaginal mucosa or determine the colonization of parts of the reproductive tract such as the oviduct (CORBEIL et al, 1989;GRAHN et al, 2005;BENCHIMOL et al, 2006). Nonetheless, the results from our study and from studies conducted in Argentina suggest that uterine lavage is an excellent diagnostic technique for determining the presence of T. foetus in herds in which artificial insemination is used, such as herd 1, or in which there is shared pasturage, with possible direct mating, as in herd 2.…”

Section: Discussionmentioning

confidence: 99%

“…The life cycle of Tritrichomonas spp is direct and there is no intermediary host (OTTE et al, 2005;CAMPERO et al, 2003. Its definitive host is cattle (Bos taurus and Bos indicus), and it colonizes their genital tract in an ascending manner without causing invasion. It becomes established on mucosal surfaces, in secretions and in the glandular lumen of the sexual organs of both bulls and cows (SINGH et al, 2004;BENCHIMOL et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Determination of presence of Tritrichomonas foetus in uterine lavages from cows with reproductive problems

González-Carmona

Sánchez-Ladino

Castañeda-Salazar

et al. 2012

Rev. Bras. Parasitol. Vet.

View full text Add to dashboard Cite

The aim of this study was to determine the presence of Tritrichomonas foetus in two dairy herds on the Altiplano Cundiboyacense. Twenty-one low-volume uterine lavages from cows with a history of reproductive problems in two dairy herds located in the municipality of Sibaté (Cundinamarca) and Ventaquemada (Boyacá) were evaluated. In the first herd, 10 cows were sampled and in the second, 11 cows, based on three inclusion criteria. The uterine lavages were obtained through infusion of physiological saline solution into the uterine body. The samples were centrifuged and seeded in Tritrichomonas basal medium for 10-15 days at 37 ºC. The protozoa were evaluated on the day of sampling and 10 and 15 days after incubation by means of direct viewing under a dark-field microscope. Positive samples were stained with Wright and Lugol to identify the morphological characteristics. This study showed that T. foetus was present in 61.8% of the animals sampled. The determination that T. foetus was present in 61.8% of the samples analyzed is a significant finding given that in the herds evaluated, this agent had not previously been diagnosed.

show abstract

“…Inhibition of cell division and endometrial inflammation were detected in vitro in oviduct organ culture models (Benchimol et al 2006;Ma et al 2011) .…”

Section: Pathogenesismentioning

confidence: 99%

Comparative aspects of immunity and vaccination in human and bovine trichomoniasis: a review

Chapwanya

Usman

Irons

2015

Trop Anim Health Prod

View full text Add to dashboard Cite

Trichomonas vaginalis and Tritrichomonas foetus are important extracellular protozoans that cause, respect i v e l y, h u m a n a n d b o v i n e v e n e r e a l d i s e a s e s . Trichomonads are extracellular parasites that primarily inhabit the genital tracts of the mammalian hosts where they overcome the mucus barrier and parasitize mucosa by contact-dependent or contact-independent cytotoxicity. Transient immunity is usually achieved by the host after clinical infection. At present, vaccination in cattle reduces infection rates and reproductive wastage in affected herds. After vaccination, immunoglobulin G (IgG) levels increase in systemic circulation while immunoglobulin A (IgA) levels rise in the vagina. Only moderate protection is conferred by means of vaccination. Future vaccine development strategies are needed for cattle to enhance the antigenic component or use adjuvant that strongly activates the innate immune response to produce safe and potent vaccines. This paper reviews the current knowledge of the immunology of trichomoniasis infection and the challenges and potential of vaccines in the control of the infection in human and bovine trichomoniasis.

show abstract

Interaction of Tritrichomonas foetus and the bovine oviduct in an organ culture model

Cited by 5 publications

References 18 publications

Apoptosis and cell proliferation in the mouse model of embryonic death induced by Tritrichomonas foetus infection

Apoptosis and cell proliferation in the mouse model of embryonic death induced by Tritrichomonas foetus infection

Determination of presence of Tritrichomonas foetus in uterine lavages from cows with reproductive problems

Comparative aspects of immunity and vaccination in human and bovine trichomoniasis: a review

Contact Info

Product

Resources

About