Insulin templated synthesis of single-crystalline silver nanocables with ultrathin Ag cores

Lü, Tao; Gao, Yukun; Wu, P.L.; Li, Xiong; Gao, Faming

doi:10.1039/c5ra04780c

Cited by 6 publications

(3 citation statements)

References 22 publications

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“…The enzyme entrapment uses amyloid hydrogel conjugated with α‐synuclein fibrils [ 192 ] and insulin amyloid fibrils conjugated with uncharged, luminescent polymers, [ 193 ] and silver nanocables. [ 194 ] Taheri et al reported a AuNPs conjugated amyloid fibrils based conductive nanoscaffold for PD biosensing. [ 195 ] Recently, Liu et al developed scFv antibodies (called W20) conjugated to PEGylated SPIONs of 12 nm size, targeting oligomers for PD diagnosis with advanced BBB bypassing ability and higher specificity in the oligomer area of PD brain compared with healthy mice.…”

Section: Nanodiagnostic Approaches For Pdmentioning

confidence: 99%

Nanotechnology‐Based Strategies for Early Diagnosis of Central Nervous System Disorders

Hanif

Muhammad

Niu

et al. 2021

Advanced NanoBiomed Research

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Central nervous system (CNS) disorders feature the progressive and selective loss of normal brain functions. CNS disorders often include an irreversible physiological and anatomical loss of neurons that can lead to dysfunction in various parts of the brain and eventually death. Glioblastoma multiforme (GBM) and neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) are hard to be diagnosed at an early stage for the prevention of disease propagation. Such diagnosis is vital for the timely commencement of actual treatments. Nanotechnology brings new diagnosis hope for CNS disorders as it provides ultrasensitive detection for more specific biomarkers. Herein, the recent progress in techniques development for detecting pathological biomarkers for GBM, AD, and PD is summarized, in particular, the principles that govern the design of these sensors, blood–brain barrier (BBB) dysfunction, and its integrity during disease development. Finally, a perspective on future directions to further advance and improve the early‐stage diagnosis of CNS disorders is presented.

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Section: Nanodiagnostic Approaches For Pdmentioning

confidence: 99%

Nanotechnology‐Based Strategies for Early Diagnosis of Central Nervous System Disorders

Hanif

Muhammad

Niu

et al. 2021

Advanced NanoBiomed Research

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“…Tao's group synthesized silver nanocables by using a mixture (insulin fibrils with AgSO 4 salt) in the presence of NaBH 4 salt as a reducing agent. [39] Furthermore, insulin fibrils, which have several micrometers long and small uniform diameters, provide amide sites for controlling and identifying inorganic substrates capable of forming silver nanocables in a limited space. In another study, gold nanoprisms were prepared successfully by using lemongrass extract.…”

Section: Noble Metal-based Materialsmentioning

confidence: 99%

Inorganic Nanomaterials for Photothermal‐Based Cancer Theranostics

Wen

Tamarov

Happonen

et al. 2020

Advanced Therapeutics

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Inorganic photothermal agents (PTAs) have attracted considerable attention in cancer theranostics due to their unique features such as high photothermal conversion efficacy, excellent photothermal stability, and straightforward functionalization. The first part of this Review summarizes progress in methods for synthesizing PTAs, then considers in vitro photothermal evaluations, as well as in vivo photothermal-based applications that attempt to overcome different barriers in cancer theranostics. Next, a clinical trial with an inorganic PTA is described. The final part of the Review examines the challenges and possibilities for successful transfer of inorganic PTAs from the laboratory to the clinic.

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“…Tao et al . developed silver nanocables using insulin amyloid fibrils with various functionalities and potential applications in conductive materials, sensors and catalysts 19 . Moreover, amyloid fibrils have shown fruitful applications in tissue engineering.…”

Section: Introductionmentioning

confidence: 99%

Assembly of Gold Nanorods on HSA Amyloid Fibrils to Develop a Conductive Nanoscaffold for Potential Biomedical and Biosensing Applications

Taheri

Akhtari

Moghadam

et al. 2018

Sci Rep

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Today, Gold Nanorods have promised variety of applications in conjugation with biomolecules of interest. Discovery of functional amyloids has also been highlighted with possible use in designing high performance materials. To exploit dual properties of both Nano and Bio counterparts in new functional materials, this effort has focused on synthesis of a potential hybrid system of Gold nanorods (GNRs) and HSA amyloid fibrils to develop a conductive nanoscaffold. UV-Vis spectroscopy, Thioflavin T (ThT) assay, Far-UV Circular Dichroism (CD) spectropolarimetry, fluorescence and Transmission Electron microscopy were used to characterize formation of the nanostructures and amyloid fibrils. Surface plasmon resonance of GNRs was also monitored upon interaction with HSA amyloid fibrils, showing that the plasmonic component of the hybrid system has maintained its characteristic rod morphology without any perturbations. Analysis of Nyquist plots for the hybrid nanoscaffold showed that the electronic behavior of the hybrid system has been enhanced due to the presence of the assembled GNRs. Results of this investigation highlight the possibility of fabricating hybrid nano-bioscaffolds as promising candidates in versatile biomedical and biosensing applications.

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Insulin templated synthesis of single-crystalline silver nanocables with ultrathin Ag cores

Abstract: Ultrathin single-crystalline silver nanocables (13 nm core diameter, 1.5 nm sheath thickness) were self-assembled by using insulin fibril templates.

Cited by 6 publications

References 22 publications

Nanotechnology‐Based Strategies for Early Diagnosis of Central Nervous System Disorders

Nanotechnology‐Based Strategies for Early Diagnosis of Central Nervous System Disorders

Inorganic Nanomaterials for Photothermal‐Based Cancer Theranostics

Assembly of Gold Nanorods on HSA Amyloid Fibrils to Develop a Conductive Nanoscaffold for Potential Biomedical and Biosensing Applications

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