Initial Studies on Alkaloids from Lombok Medicinal Plants

Hadi, Surya; Bremner, John B.

doi:10.3390/60100117

Cited by 71 publications

(49 citation statements)

References 13 publications

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“…This was carried out in order to determine the presence of glycosides, tannin, saponin, phenol, alkaloid and flavonoid in the plant extracts (Hadi and Bremner, 2001;Wadood et al (2013;Desphande and Kadam, 2013).…”

Section: Qualitative Phytochemical Analysis Of Plant Extractsmentioning

confidence: 99%

In-ovo biological activities of Phyllanthus amarus leaf extracts against Newcastle disease virus

Faeji¹,

Oladunmoye²,

Adebayo³

et al. 2017

J. Med. Plants Res.

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Newcastle disease virus is a paramyxovirus which causes Newcastle disease in birds. Investigation was done on the effect of leaf extract of Phyllanthus amarus against Newcastle disease virus (NDV) using an in-ovo assay. Nine to eleven day-old viable embryonated chicken eggs (ECE) were used for the assay, these were divided into six groups of six eggs each. Methanol, aqueous and n-hexane extracts of the plant leaves were administered to the various groups at concentrations varying from 50 to 5 mg/ml. Embryonated eggs were incubated and embryo survival was monitored daily. Negative control and diluents control groups received phosphate buffer saline (PBS) and dimethly suphoxide (DMSO), respectively. The other group was uninoculated while a virus control group received 100 EID 50 /0.1 ml NDV alone. Bacteria free allantoic fluid from the embryonated eggs in different treatment groups were harvested and collected for spot hemagglutination (HA) test and HA assay to detect the presence of NDV viral particles and the viral titre, respectively. Leaf extracts were assayed for presence of phytochemicals and antioxidant potentials. It was observed from the results that the extract was toxic to the embryo at a concentration above 50 mg/ml and further results showed that the HA viral titre reduction was directly proportional to increasing extract concentration. The phytochemical assays of leaf extract revealed the presence of phytochemicals including alkaloids, tannins, saponins, flavonoids, phenols, steroids, glycosides. The current findings have demonstrated that leaf extract from P. amarus has potentials of medicinal value as well as antiviral activity against NDV in-ovo. Further experimental assays using live animal models are recommended to validate the use of P. amarus plant extract in therapeutic measure in chickens.

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Section: Qualitative Phytochemical Analysis Of Plant Extractsmentioning

confidence: 99%

In-ovo biological activities of Phyllanthus amarus leaf extracts against Newcastle disease virus

Faeji¹,

Oladunmoye²,

Adebayo³

et al. 2017

J. Med. Plants Res.

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“…The new indole alkaloid, alstonamine and a sitsirikine type indole alkaloid, rhazimanine, have been isolated from the leaves of A. scholaris by Atta-ur-Rahman and Alvi (1987). Hadi and Bremner (2001) tested A. scholaris for antimalarial properties of alkaloids obtained from young plants leaves. Patrick et al (2005) isolated different types of alkaloids from the leaves of the Philippine medicinal plant, A. scholaris.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical and antibacterial properties of leaves of Alstonia scholaris R. Br.

Khyade¹,

M²,

Vaikos³

et al. 2009

Afr. J. Biotechnol.

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Phytochemical and antibacterial activity of leaves of Alstonia scholaris R.Br. was investigated. The different solvent extracts showed the presence of Iridoids, alkaloids, coumarins, flavonoids, leucoanthocyanins, reducing sugars, simple phenolics, steroids, saponins and tannins. Antibacterial activity was tested against both Gram +ve and -ve organisms. The methanol leaves extract exhibited broad-spectrum antibacterial activity against tested organisms. Maximum activity was exhibited against Bacillus subtilis followed by Escherichia coli and Staphylococcus aureus. Chloroform and acetone leaf extracts exhibited lesser activity, while petroleum ether extract showed no inhibition.

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“…People in Aceh (Erdelen et al1999) and East Lombok, Indonesia (Hadi and Bremner 2001), Malaysia (Salleh 1997), and Karnataka Province, India (Shankar et al 1999) use the species Alstonia scholaris to combat malaria and fever. Carica papaya L. (leaves, stem, roots, and flowers) is used to treat malaria in West Lombok, Indonesia (Hadi and Bremer 2001).…”

Section: Plants Used For Pain And/ or Fevermentioning

confidence: 99%

The wild plants used as traditional medicines by indigenous people of Manokwari, West Papua

Lense

2012

Biodiversitas

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Lense O. 2012. The wild plants used as traditional medicines by indigenous people of Manokwari,. The aims of the research were to identify the main plant species which are used as traditional medicines by native people in Manokwari District, West Papua Province and also to describe the method of preparation and uses of some of the medicinal plants. This research was conducted in seven sub-districts, ie. Manokwari, Ransiki, Kebar, Wasior, Mimyambouw, Merdey and Anggi-Sururey subDistrict. Information recorded including methods of diagnosis and treatment of diseases, tribal name of a plant they used for treating disease (s), part of the plant used, preparation and mode of application, and whether the plant is used alone or in combination with other plants. Results indicate that the indigenous people in Manokwari District have been using at least 99 plant species (93 genera and 59 families) as sources of medicines. Most of these traditional medicinal plants are commonly gathered from the local tropical rainforest communities. At least 40 kinds of sickness and injuries such as malaria, fever, and wounds can be treated by using traditional medicinal plants from Manokwari District. Research also found that all parts of plants used, but leaf extracts are the most common part of the plant used for treating medical condition.

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Initial Studies on Alkaloids from Lombok Medicinal Plants

Cited by 71 publications

References 13 publications

In-ovo biological activities of Phyllanthus amarus leaf extracts against Newcastle disease virus

In-ovo biological activities of Phyllanthus amarus leaf extracts against Newcastle disease virus

Phytochemical and antibacterial properties of leaves of Alstonia scholaris R. Br.

The wild plants used as traditional medicines by indigenous people of Manokwari, West Papua

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