Abstract:O crescimento da hidroxiapatita - HA, tanto no meio biológico quanto em soluções aquosas como a Synthetic Body Fluid - SBF, ocorre em meio contendo, além dos elementos Ca e P, elementos-traços essenciais tais como: Mg2+, HCO3-, K+ e Na+. Alguns destes elementos são conhecidos como inibidores do crescimento da HA, como Mg2+ e HCO3-. Neste trabalho, estudou-se a influência dos íons K+ e Mg2+ na formação de apatitas sobre substratos metálicos de Ti c.p. previamente tratados com NaOH 5M. Os efeitos destes íons no … Show more
“…In previous works Braga [12] and Bini [33] verified that the fast melting and solidification process of the metallic surface at ambient pressure and atmosphere lead to the build-up of different stoichiometric and non-stoichiometric titanium oxides. Titanium is able to absorb about 40% of atomic oxygen into its crystal lattice (∼18% m/m) in solid interstitial solution [12,13]. Thus, the energy supplied by the laser benefits the diffusion of oxygen atoms into the ␣-Ti network.…”
Section: Surface Irradiation By Lasermentioning
confidence: 99%
“…The likely factors are related to the best remodeling activity on the bone/implant interface observed in implants with rough morphology. This generates an increase of retention of blood clot, of the area of implant/tissue surface and the cellular migration and proliferation [9][10][11][12][13][14][15][16].…”
Apatite coating was applied on titanium surfaces modified by Nd:YVO 4 laser ablations with different energy densities (fluency) at ambient pressure and atmosphere. The apatites were deposited by biomimetic method using a simulated body fluid solution that simulates the salt concentration of bodily fluids. The titanium surfaces submitted to the fast melting and solidification processes (ablation) were immersed in the simulated body fluid solution for four days. The samples were divided into two groups, one underwent heat treatment at 600 • C and the other dried at 37 • C. For the samples treated thermally the diffractograms showed the formation of a phase mixture, with the presence of the hydroxyapatite, tricalcium phosphate, calcium deficient hydroxyapatite, carbonated hydroxyapatite and octacalcium phosphate phases. For the samples dried only the formation of the octacalcium phosphate and hydroxyapatite phases was verified. The infrared spectra show bands relative to chemical bonds confirmed by the diffraction analyses. The coating of both the samples with and without heat treatment present dense morphology and made up of a clustering of spherical particles ranging from 5 to 20 m. Based on the results we infer that the modification of implant surfaces employing laser ablations leads to the formation of oxides that help the formation of hydroxyapatite without the need of a heat treatment.
“…In previous works Braga [12] and Bini [33] verified that the fast melting and solidification process of the metallic surface at ambient pressure and atmosphere lead to the build-up of different stoichiometric and non-stoichiometric titanium oxides. Titanium is able to absorb about 40% of atomic oxygen into its crystal lattice (∼18% m/m) in solid interstitial solution [12,13]. Thus, the energy supplied by the laser benefits the diffusion of oxygen atoms into the ␣-Ti network.…”
Section: Surface Irradiation By Lasermentioning
confidence: 99%
“…The likely factors are related to the best remodeling activity on the bone/implant interface observed in implants with rough morphology. This generates an increase of retention of blood clot, of the area of implant/tissue surface and the cellular migration and proliferation [9][10][11][12][13][14][15][16].…”
Apatite coating was applied on titanium surfaces modified by Nd:YVO 4 laser ablations with different energy densities (fluency) at ambient pressure and atmosphere. The apatites were deposited by biomimetic method using a simulated body fluid solution that simulates the salt concentration of bodily fluids. The titanium surfaces submitted to the fast melting and solidification processes (ablation) were immersed in the simulated body fluid solution for four days. The samples were divided into two groups, one underwent heat treatment at 600 • C and the other dried at 37 • C. For the samples treated thermally the diffractograms showed the formation of a phase mixture, with the presence of the hydroxyapatite, tricalcium phosphate, calcium deficient hydroxyapatite, carbonated hydroxyapatite and octacalcium phosphate phases. For the samples dried only the formation of the octacalcium phosphate and hydroxyapatite phases was verified. The infrared spectra show bands relative to chemical bonds confirmed by the diffraction analyses. The coating of both the samples with and without heat treatment present dense morphology and made up of a clustering of spherical particles ranging from 5 to 20 m. Based on the results we infer that the modification of implant surfaces employing laser ablations leads to the formation of oxides that help the formation of hydroxyapatite without the need of a heat treatment.
“…Therefore, other techniques have been used such as the biomimetic method, which mimics the biological process of hard tissue formation in the body (Aparecida et al. ).…”
mentioning
confidence: 99%
“…Although, HA coated implants integrate more rapidly than uncoated implants do, there are some disadvantages associated with this process, such as the thick and non-uniform coating that facilitates the appearance of fractures or cracks in the deposited material (Guo & Li 2004), which may be partially dissolved/reabsorbed after long periods without functioning (Barrere et al 2001;Legeros 2002). Therefore, other techniques have been used such as the biomimetic method, which mimics the biological process of hard tissue formation in the body (Aparecida et al 2005).…”
It was concluded that the implants LS, HAB, and HABT presented physicochemical and topographical properties superior to those of AS and MS and favored the osseointegration process in the shorter periods. In addition, HAB showed the best results when compared with other surfaces.
“…Estudos mostram que HA promove adesão, proliferação e diferenciação de osteoblastos. [372][373][374][375] Desta forma, recentemente, compósitos produzidos a partir de PMMA e nanopartículas de fosfatos e carbonatos de cálcio estão sendo explorados devido às suas propriedades físicas e biológicas semelhantes às da ECM, visando superar as desvantagens e satisfazer os requisitos para um substituto ósseo ideal. 372 O aumento da porosidade destes materiais também ocasiona crescimento ósseo acelerado ao redor do substituto.…”
Section: Hidrogéis Contendo Col1 E Macromoléculas Sintéticasunclassified
Agradeço a Deus pelo dom da vida, por todas as bençãos e graças.Ao Eduardo pelo suporte, amor e companheirismo que me deixam segura para seguir adiante.Aos meus pais Ana e Carlos, às minhas irmãs, por serem a minha rede de apoio.Aos alunos que de forma direta permitiram o desenvolvimento dos projetos aqui descritos: Camila,
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