Influence of the Combination of Infrared and Red Laser Light on the Healing of Cutaneous Wounds Infected by <i>Staphylococcus aureus</i>

Santos, Nicole Ribeiro Silva; Sobrinho, João Batista de Macedo; Almeida, Paulo Fernando de; Ribeiro, Adriana Alves; Cangussú, Maria Cristina Teixeira; Santos, Jean Nunes dos; Pinheiro, António Luiz Barbosa

doi:10.1089/pho.2009.2749

Cited by 32 publications

(19 citation statements)

References 16 publications

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“…The present study used a combination of infrared (λ808 nm) and red laser (λ660 nm), because some studies have suggested that this association is more effective in reducing the inflammatory process and accelerating tissue repair, as different wavelengths would have different absorption and penetration ( 12 , 27 - 29 ). Irradiation of the root surface with infrared laser was based on findings of Carvalho et al ( 9 ) and irradiation of the alveolar walls and vestibular/palatine mucosa with red laser was based on findings of Vilela et al ( 10 ), who showed less root resorption areas in laser groups using their respective wavelengths.…”

Section: Discussionmentioning

confidence: 99%

Laser phototherapy induces angiogenesis in the periodontal tissue after delayed tooth replantation in rats

et al. 2018

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BackgroundLaser phototherapy (LPT) has been suggested as a new therapeutic tool to improve the repair of replanted teeth. However, its effects and mechanism of action are not yet completely understood.ObjectivesThis study evaluated histologically the effect of laser phototherapy (LPT) λ808 and λ660 nm on angiogenesis in the periodontal tissue of replanted teeth in rats.Material and MethodsTwenty maxillary right incisors were extracted from twenty Wistar rats and randomly assigned to four groups (n = 5): PN – teeth were stored in paper napkin for 45 min; WM – teeth were immersed in 20 ml of UHT whole cow milk for 45 min; PNL and WML – teeth received the same treatment described for PN and WM, respectively, plus LPT at λ808 and λ660 nm. All root canals were prepared and filled with calcium hydroxide paste. The animals were euthanized 15 days after tooth replantation and angiogenesis was scored by blood vessel counting in the area of periodontal ligament and alveolar bone, using the ImageJ software. Data were analyzed statistically by ANOVA and Tukey’s test (α = 5%).ResultsLPT at λ808 and λ660 nm caused significant increased angiogenesis on irradiated groups (PNL and WML) when compared to the non-irradiated groups (PN and WM) (p<0.05). There was no statistically significant difference between PN and WM as well as between PNL and WML (p>0.05).ConclusionsLPT is capable of stimulating angiogenesis in vivo in the periodontal tissue of replanted teeth. Key words:Angiogenesis, lasers, tooth avulsion, tooth replantation, wound healing.

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Section: Discussionmentioning

confidence: 99%

Laser phototherapy induces angiogenesis in the periodontal tissue after delayed tooth replantation in rats

et al. 2018

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“…Low-intensity laser therapy is one of the clinical therapeutic modalities that has been used for wound healing. Previous studies of laser treatments have demonstrated that low-intensity laser therapy accelerates and facilitates wound healing 17 , 18 , 19 ) .…”

Section: Discussionmentioning

confidence: 99%

The effect of low-intensity laser therapy (LILT) on cutaneous wound healing and pain relief in rats

Koo

Yong

2015

J Phys Ther Sci

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[Purpose] This study examined the impact of low-intensity laser therapy on wound healing and pain control using a rat cutaneous wound model. [Subjects and Methods] Twenty-four adult male Sprague-Dawley rats (between 220−240 g, 7 weeks) were used in this study. The rats were anesthetized and a circular fragment of skin was removed from the dorsal region of the back by a punch with an 8-mm diameter. The animals were randomly divided into 6 groups, Groups C 1, C 3, and C 5, control groups, received no laser treatment. Groups T 1, T 3, and T 5 received laser treatment for 20 min per day for 1, 3 and 5 days, respectively. Lumbar spine and dorsal skin were extracted and processed using western blot analysis. [Results] Periodical observation showed increases in NGF expression on the skin, and decreases in c-fos expression by the spinal cord in the treatment groups compared to the control group. [Conclusion] The present findings suggest that low-intensity laser therapy could be used as an effective therapy for wound healing and pain relief, and could be further used as a clinical approach for treating cutaneous wounds.

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“…However, for the pulsed 890 nm laser, Ezzati et al [28] observed the destructive effect only when doses of 11.7 J/cm 2 were given, but not to 2.3 J/cm 2 . Santos et al [29] observed a positive effect on wound healing in infected Wistar rats on the most advanced inflammatory stages by using laser 680 and 790 nm, with dose of 5 J/cm 2 . Also, Vasheghani et al [30], despite verifying an improvement in the rat ulcers, observed no effect of the laser 890 nm, 0.396 J/cm 2 on S. aureus .…”

Section: Discussionmentioning

confidence: 99%

Effects of Low-Level Laser Therapy, 660 nm, in Experimental Septic Arthritis

et al. 2013

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The effectiveness of low-level laser therapy (LLLT) in the presence of an infectious process has not been well elucidated. The aim of the study was to evaluate the effects of LLLT in an experimental model of septic arthritis. Methods. Twenty-one Wistar rats were divided as follows: control group, no bacteria; placebo group, bacteria were inoculated; Treated group, bacteria were injected and treatment with LLLTwas performed. To assess nociception, a von Frey digital analgesimeter was applied. Synovial fluid was streaked to analyze bacterial growth. The standard strain of S. aureus was inoculated in the right knee. LLLT was performed with 660 nm, 2 J/cm2, over 10 days. After treatment, the knees were fixed and processed for morphological analysis by light microscopy. Results. It was found that nociception increases in the right knee. There was a lack of results for the seeding of the synovial fluid. The morphological analysis showed slight recovery areas in the articular cartilage and synovia; however, there was the maintenance of the inflammatory infiltrate. Conclusion. The parameters used were not effective in the nociception reduction, even with the slight tissue recovery due to the maintenance of inflammatory infiltrate, but produced no change in the natural history of resolution of the infectious process.

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Influence of the Combination of Infrared and Red Laser Light on the Healing of Cutaneous Wounds Infected by Staphylococcus aureus

Abstract: The results of the present study indicate that laser phototherapy has a positive effect on the healing of infected wounds, particularly with the association of λ680 + λ790 nm.

Cited by 32 publications

References 16 publications

Laser phototherapy induces angiogenesis in the periodontal tissue after delayed tooth replantation in rats

Laser phototherapy induces angiogenesis in the periodontal tissue after delayed tooth replantation in rats

The effect of low-intensity laser therapy (LILT) on cutaneous wound healing and pain relief in rats

Effects of Low-Level Laser Therapy, 660 nm, in Experimental Septic Arthritis

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