Influence of glycemic control on fetal lung maturity in gestations affected by diabetes or mild hyperglycemia

Luca, Ana Karina C. De; Nakazawa, CY; Azevedo, Beatriz Camargo; Rudge, Marilza Vieira Cunha; Costa, Roberto Antônio de Araújo; Calderon, Iracema de Mattos Paranhos

doi:10.1080/00016340903118018

Cited by 19 publications

(5 citation statements)

References 26 publications

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“…The variables that were found to have a p value <0.1 in the univariate analysis were entered into the model. Gestational diabetes was also entered in the model, as there is an established relationship between respiratory distress syndrome and gestational diabetes [19]. Finally, the correlation between the term delivery and the fluorescence polarisation was assessed using Pearson's correlation coefficient.…”

Section: Discussionmentioning

confidence: 99%

Caesarean section at term: the relationship between neonatal respiratory morbidity and microviscosity in amniotic fluid

Lavoué

Voguet

Laviolle

et al. 2013

European Journal of Obstetrics & Gynecology and Reproductiv

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Section: Discussionmentioning

confidence: 99%

Caesarean section at term: the relationship between neonatal respiratory morbidity and microviscosity in amniotic fluid

Lavoué

Voguet

Laviolle

et al. 2013

European Journal of Obstetrics & Gynecology and Reproductiv

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“…GM was estimated based on the arithmetic mean of six glucose values measured every two hours from 8 a.m to 6 p.m once a week. All glucose determinations were obtained by the glucose oxidase method 12 , and a GM of 66.7 mmol/L (120 mg/dL) was considered adequate.…”

Section: Methodsmentioning

confidence: 99%

Does hyperglycemia in pregnancy change fetal kidney growth?: a longitudinal prospective study

Neves

Sgarbosa

Calderon

et al. 2013

Rev. Bras. Ginecol. Obstet.

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“…Em es-tudo clínico, De Luca e cols., ao avaliar a influência do controle glicêmico sobre a maturidade pulmonar fetal em gestações acometidas por diabetes ou hiperglicemia leve, demonstraram que houve atraso na maturidade pulmonar fetal quando o controle glicêmico era inadequado, sugerindo que, nas gestações a termo, a rotina de amniocentese para a avaliação da maturidade pulmonar fetal deve ser abandonada, mas deve ser recomendada em gestações pré-termo ou quando o controle glicêmico é inadequado (43).…”

Section: Imaturidade Pulmonar Fetalunclassified

Pesquisa translacional em diabetes melito gestacional e hiperglicemia gestacional leve: conhecimento atual e nossa experiência

Rudge

Pículo

Marini

et al. 2013

Arq Bras Endocrinol Metab

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RESUMOO diabetes materno constitui um ambiente desfavorável para o desenvolvimento embrionário e feto--placentário. É uma repercussão de importância na obstetrícia moderna, visto que está associado a um risco aumentado de morbidade materna e neonatal e continua a ser um desafio médico significativo. O aumento mundial na incidência do diabetes, o aumento do diabetes tipo 2 em mulheres em idade reprodutiva e a geração cruzada da programação intrauterina do diabetes tipo 2 são as bases para o interesse crescente na utilização de modelos experimentais diabéticos, a fim de obter conhecimento sobre os mecanismos que induzem as alterações de desenvolvimento no diabetes gestacional. Vários estudos têm demonstrado os benefícios da prevenção do diabetes com intervenções no estilo de vida, melhora metabólica e controle de fator de risco cardiovascular para evitar substancialmente as complicações devastadores da doença. Apesar desses achados e a revolução recente no conhecimento científico e infinidade de novas terapias do diabetes, continua a haver uma grande lacuna entre o que foi aprendido por meio da pesquisa e o que é feito na prática da saúde pública, clínica e comunitária. O iminente impacto econômico negativo dessa complacência nos indivíduos, nas famílias e nas economias nacionais é alarmante. Espera-se que a pesquisa translacional no binômio diabetes-gravidez seja implementada em centros de excelência tanto de pesquisa básica como aplicada e complementada por estudos clínicos multicêntricos, conduzidos de forma pragmá-tica para aumentar o nível de evidência científica com recursos diagnósticos e propedêuticos mais confiáveis. Arq Bras Endocrinol Metab. 2013;57(7):497-508 Descritores Diabetes; gestação; modelos animais; pesquisa translacional; incontinência urinária ABSTRACT Maternal diabetes constitutes an unfavorable environment for fetal-placental and embryonic development. It is has important repercussion in modern obstetrics, since it is associated to an increased risk of neonatal and maternal morbidity, and it still is a significant medical challenge. The increased occurrence of diabetes worldwide, the increase in diabetes type 2 in women at reproductive age and the crossed generation of intrauterine programming for diabetes type 2 are the bases for the growing interest in utilization of diabetic experimental samples, with the aim to acquire knowledge about the mechanisms that induce development alterations in gestational diabetes. Several studies have shown the benefits of diabetes prevention, with interventions in lifestyle, metabolic improvement and control of cardiovascular risk factors to substantially prevent the complications of this devastating disease. Despite these findings, the recent revolution in the scientific knowledge, and the infinite number of new therapies for diabetes, there is still a large gap between what was learned through research and what is really done in public, clinical and community health. The negative economic impact of this complacency in people, families, and national econom...

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Influence of glycemic control on fetal lung maturity in gestations affected by diabetes or mild hyperglycemia

Abstract: Our results suggest that in term pregnancies routine amniocentesis for the assessment of fetal lung maturity should be abandoned. In preterm pregnancies, or when glycemic control is inadequate it is recommended.

Cited by 19 publications

References 26 publications

Caesarean section at term: the relationship between neonatal respiratory morbidity and microviscosity in amniotic fluid

Caesarean section at term: the relationship between neonatal respiratory morbidity and microviscosity in amniotic fluid

Does hyperglycemia in pregnancy change fetal kidney growth?: a longitudinal prospective study

Pesquisa translacional em diabetes melito gestacional e hiperglicemia gestacional leve: conhecimento atual e nossa experiência

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