Indocyanine Green Videoangiography of Hemorrhagic Retinal Arterial Macroaneurysms

Abstract

We examined 3 patients with isolated retinal macroaneurysms and secondary hemorrhage by standard fluorescein angiography (FA) and indocyanine green (ICG) angiography. In contrast to standard FA, ICG videoangiography clearly demonstrated the lesion to be pulsatile, contiguous with the arterial wall and pathognomonic of an isolated retinal artery macroaneurysm. ICG with its absorption and emission peak in the near-infrared range penetrates hemorrhage to a greater degree than does blue or green light of conventional FA. ICG can be essential in delineating the specific cause of the bleeding and allow the physician to choose the correct specific form of treatment needed.

Indocyanine green angiography in isolated primary retinal arterial macroaneurysms

“…Indocyanine exiting and emitting light is much less affected by haemoglobin and melanin than that of fluorescein, and therefore it is a useful tool for those diseases involving haemorrhages or pigmentary abnormalities. In agreement with other reports (Parodi & Ravalico 1995;Schneider et al 1997), in our study we observed that in some cases indocyanine green angiography is able to demonstrate RAM under conditions inadequate for other procedures, including biomicroscopy and fluorescein angiogaphy. Thus it may be helpful to rule out other diagnoses until the hemorrhage clears spontaneously.…”

Spontaneous involution of a large retinal arterial macroaneurysm

“…Because this angiographic finding is typical of retinal macroaneurysms (Schneider et al 1997), we diagnosed this mass lesion as a large retinal macroaneurysm. ICG angiography, with its absorption and emission peak in the near-infrared spectrum, allows observation of the lesion through hemorrhage (Flower & Hochheimer 1973;Hayashi & DeLaey 1985;Bischoff & Flower 1985).…”

Imaging of macroaneurysms occurring during retinal vein occlusion and diabetic retinopathy by indocyanine green angiography and high resolution optical coherence tomography

“…The presence of blood, hard exsudates and/or dye leakage may impair their visualization by fundus photography and/or fluorescein angiography (FA) [3]. It has previously been shown that indocyanine green angiography (ICGA) may be useful for the detection of microaneurysms [6] and of arterial MAs [7][8][9][10]. To our knowledge, there is no reported data on the prevalence of MAs during diabetic retinopathy (DR).…”