Abstract:ABSTRACT.Purpose: The study was carried out to describe the indocyanine green angiographic findings in isolated primary retinal arterial macroaneurysms and their contribution to the diagnosis of this condition. Methods. Fluorescein and indocyanine green angiography examination techniques were used to study isolated primary retinal arterial macroaneurysms in 8 consecutive patients with retinal or preretinal haemorrhage over a period of 12 months. Results. The fluorescein angiography examination showed the macro… Show more
“…In the cases where hemorrhage blocks visualization of RAM in fundus photograph and the diagnosis with FA image is also not conclusive, ICGA is especially beneficial in that it can pinpoint the exact location of the RAM in such cases. [ 5 38 39 40 41 42 43 44 45 ] In the present report, all cases were clearly and correctly diagnosed by using all those methods. We think that an organic combination of those methods can guaranty the diagnosis.…”
Purpose:
To evaluate the outcome of the combined approach between intravitreal ranibizumab (IVR) and focal laser photocoagulation (FLP) in the treatment of symptomatic retinal arterial macroaneurysm (RAM).
Methods:
A total of 10 patients were included in this clinical case series report. They were diagnosed with symptomatic RAM (one eye in each) and assessed by a comprehensive ophthalmologic examination, including fluorescein angiography (FA), optical coherence tomography angiography (OCT-A), and indocyanine green angiography (ICGA). All patients were treated with an IVR followed by an FLP 2 weeks later. If necessary, a second IVR was given 1 month after the first one (or 2 weeks after the first FLP), which was followed by a second FLP treatment 2 weeks later in the needed cases. All cases were followed up for 6 months after the last treatment.
Results:
Both the retina hemorrhage and edema were resolved by the treatment. No ocular and/or systemic side effects were evident, and no recrudescence of RAM was seen within the 6 months of follow-up.
Conclusion:
The combined treatment of IVRs and FLPs was successful in the management of symptomatic RAM.
“…In the cases where hemorrhage blocks visualization of RAM in fundus photograph and the diagnosis with FA image is also not conclusive, ICGA is especially beneficial in that it can pinpoint the exact location of the RAM in such cases. [ 5 38 39 40 41 42 43 44 45 ] In the present report, all cases were clearly and correctly diagnosed by using all those methods. We think that an organic combination of those methods can guaranty the diagnosis.…”
Purpose:
To evaluate the outcome of the combined approach between intravitreal ranibizumab (IVR) and focal laser photocoagulation (FLP) in the treatment of symptomatic retinal arterial macroaneurysm (RAM).
Methods:
A total of 10 patients were included in this clinical case series report. They were diagnosed with symptomatic RAM (one eye in each) and assessed by a comprehensive ophthalmologic examination, including fluorescein angiography (FA), optical coherence tomography angiography (OCT-A), and indocyanine green angiography (ICGA). All patients were treated with an IVR followed by an FLP 2 weeks later. If necessary, a second IVR was given 1 month after the first one (or 2 weeks after the first FLP), which was followed by a second FLP treatment 2 weeks later in the needed cases. All cases were followed up for 6 months after the last treatment.
Results:
Both the retina hemorrhage and edema were resolved by the treatment. No ocular and/or systemic side effects were evident, and no recrudescence of RAM was seen within the 6 months of follow-up.
Conclusion:
The combined treatment of IVRs and FLPs was successful in the management of symptomatic RAM.
“…Up to now, the most reliable and common methods for detection of RAMs have been ICG and fluorescein angiography (FA) [ 1 , 17 ]. However, we achieved noninvasive detection of RAMs without dye injection in all our cases by means of SSADA based OCT angiography.…”
BackgroundOptical coherence tomography angiography is a novel imaging technique that allows dyeless in vivo visualization of the retinal and choroidal vasculature. The purpose of this study was to describe optical coherence tomography (OCT) angiography findings in patients with retinal arterial macroaneurysms (RAMs).MethodsThree eyes of three patients with RAMs were retrospectively included. Fundus photography, OCT, fluorescein angiography (FA), and OCT angiography were performed. The entire imaging data was analyzed in detail.ResultsOCT angiography could detect the RAMs noninvasively without dye injection. By simultaneously observing the OCT scans, it was possible to determine the depth of the RAMs in the retina, to detect the exact localization in relation to the main vessel, and to determine the level of blood flow in the RAMs.ConclusionsOCT angiography can clearly visualize RAMs without use of a dye. It also allows layer-specific observation of blood flow in each layer of the RAM. OCT angiography provides additional dynamic information on RAMs, which is not obtained with FA and facilitates a better understanding of its morphology and activity. This information in combination with ICG and fluorescein angiography can help to optimize direct laser treatment.
“…The presence of blood, hard exsudates and/or dye leakage may impair their visualization by fundus photography and/or fluorescein angiography (FA) [3]. It has previously been shown that indocyanine green angiography (ICGA) may be useful for the detection of microaneurysms [6] and of arterial MAs [7][8][9][10]. To our knowledge, there is no reported data on the prevalence of MAs during diabetic retinopathy (DR).…”
MAs can develop during the course of RVO and DR. ICGA and HR-OCT improves the identification of capillary and venous MAs, and may thus be of interest to better identify sites of blood-retinal barrier rupture during chronic macular edema due to RVO or DR.
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