Incidence of Dimethylacetamide Induced Toxic Liver Injury among Workers in a Synthetic Fiber Manufacturing Company

Jang, Yong Seok; Yoon, Seong Yong; Jo, Seong Yong; Choi, Tae Sung; Yoo, Jay Young; Woo, Kuck Hyun; Ha, Bong Goo; Jung, Sang Jae; Chun, Bo Young; Kim, Jin Seok

doi:10.35371/kjoem.2006.18.3.246

Cited by 3 publications

(1 citation statement)

References 13 publications

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“…The close observation of 997 workers who worked in synthetic fiber production using DMAc from 1 February 2000 to 30 June 2004 revealed 72 cases of suspected toxic hepatitis ( 13 ). There were no cases that occurred within 2 weeks of starting employment, with most cases occurring between 2 and 17 weeks of starting employment.…”

Section: Occupational Hepatic Disorders In Koreamentioning

confidence: 99%

Occupational Hepatic Disorders in Korea

Kim

2010

J Korean Med Sci

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Occupational hepatic disorders are classified into toxic hepatitis, viral hepatitis, and chemical-induced malignancy in Korea. Toxic hepatitis cases were reported in workers who were exposed to dimethylformamide, dimethylacetamide, or trichloroethylene. Pre-placement medical examination and regular follow-up are necessary to prevent the development of toxic hepatitis. Viral hepatitis was chiefly reported among health care workers such as doctors, nurses and clinical pathology technicians who could easily be exposed to blood. Preventive measures for these groups therefore include vaccination and serum monitoring programs. Hepatic angiosarcoma caused by vinyl chloride monomer (VCM) exposure is a very well known occupational disease and it has not been officially reported in Korea yet. Some cases of hepatocellular carcinoma were legally approved for compensation as an occupational disease largely by overwork and stress, but not supported by enough scientific evidence. Effort to find the evidence of its causal relationship is needed.

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Section: Occupational Hepatic Disorders In Koreamentioning

confidence: 99%

Occupational Hepatic Disorders in Korea

Kim

2010

J Korean Med Sci

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Current status of liver diseases in Korea: Toxic and alcoholic liver diseases

Kim

2009

Korean J Hepatol

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The study of the epidemiology of toxic liver injury has been limited in Korea. The number of hospitalizations for toxic liver injury has been estimated to be 2,400 persons per year. About 30~40% of fulminant hepatitis was attributed to toxic hepatitis. The frequent causative agents of toxic hepatitis in Korea are herbal medicines (34-40%), folk remedies (23-34%), and prescribed medicines (24-55%). However, the most common agents causing severe liver injury including fulminant hepatitis are herbal medicine and folk remedies. Antituberculosis drugs and acetaminophen are two common causes of fulminant hepatitis among prescribed drugs. Alcohol is one of the leading causes of chronic liver disease in Korea. No nationwide study on the epidemiology of alcoholic liver disease (ALD) has been carried out, but 7-31% of cirrhosis has been reported to be alcoholic in a few single-center studies. Alcohol could be a risk factor for the development of hepatocellular carcinoma (HCC) in chronic viral hepatitis. Several studies have shown that alcohol increased the risk of HCC in liver cirrhosis with HBsAg or anti-HCV. Furthermore, alcoholic cirrhosis with occult hepatitis B virus infection increased the risk of HCC.

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A review of life table applications and an introduction of its application method

Shin¹,

Choi²

2013

Journal of the Korean Data and Information Science Society

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The lift table summarized and calculated the life expectancy at each ages according to aging. In this study, we tried to re-classify and summarized the application of the life table because the life table can be applied to several research and industry area. We utilized the whole papers published in Korea and international until 2011 and we considered several classification standards based on application, base period, gender, and observation period. Each standard divides the life tables into two or three categories. The standard of application groups them into general and applied life tables. The standard of base period is divided into two parts: abridge life table using the unit of 5 years and complete life table of one year. According to gender, life tables are classified in male, female, and unisex life tables. According to complete life table, they are period life tables and cohort life tables. This study contributes to inform how life tables can be employed in many other areas by analyzing how the life tables are constructed.

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Incidence of Dimethylacetamide Induced Toxic Liver Injury among Workers in a Synthetic Fiber Manufacturing Company

Cited by 3 publications

References 13 publications

Occupational Hepatic Disorders in Korea

Occupational Hepatic Disorders in Korea

Current status of liver diseases in Korea: Toxic and alcoholic liver diseases

A review of life table applications and an introduction of its application method

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