2017
DOI: 10.1016/j.rbre.2016.11.005
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Inadequate pain relief among patients with primary knee osteoarthritis

Abstract: Our findings indicate that improvements are needed in the management of pain in knee OA in order to achieve better outcomes in terms of pain relief, function and quality of life.

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Cited by 12 publications
(9 citation statements)
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“…Although OA shows local inflammation, the reduced strength and muscle mass also are observed in OA patients, as well as in RA patients. Due to theses alterations, OA patients may show reduction of functionality [ 12 , 15 , 17 , 18 ], increase in risk of falls and fractures [ 18 ].…”
Section: Introductionmentioning
confidence: 99%
“…Although OA shows local inflammation, the reduced strength and muscle mass also are observed in OA patients, as well as in RA patients. Due to theses alterations, OA patients may show reduction of functionality [ 12 , 15 , 17 , 18 ], increase in risk of falls and fractures [ 18 ].…”
Section: Introductionmentioning
confidence: 99%
“…13 Studies have reported dissatisfaction among NSAID users with respect to adequate pain relief. 14,15 Also, NSAIDs, while causing the known adverse effects, do not halt disease progression. 16 In this scenario, supplementation of nutrients, natural or synthetic, is a recent strategy for managing and preventing OA.…”
Section: Introductionmentioning
confidence: 99%
“…La alteración de todos esos tejidos, activa el sistema nociceptivo que genera dolor. [22][23][24] Debido a ese estímulo, se vierten dentro de la articulación mediadores de tipo inflamatorio como: bradicinina, histamina, prostaglandinas, ácido láctico, sustancia P y péptido C, que desde el punto de vista genético está relacionado con la calcitonina. Todos esos mediadores, disminuyen el umbral doloroso de los tejidos dentro de la articulación y hacen que los mismos sean más sensibles a la respuesta dolorosa.…”
Section: Características Generales Del Dolor En La Artrosis De Rodillaunclassified