In vitro studies to assess the antidiabetic, anti-cholinesterase and antioxidant potential of Spergularia rubra

Vinholes, Juliana; Grosso, Clara; Andrade, Paula B.; Gil‐Izquierdo, Ángel; Valentão, Patrı́cia; Pinho, Paula Guedes de; Ferreres, Federico

doi:10.1016/j.foodchem.2011.04.098

Cited by 106 publications

(73 citation statements)

References 33 publications

(38 reference statements)

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“…Moreover, the results obtained can be attributed, at least partially, to the presence in the new beverages of bioactive flavonols, flavones, and flavanones, as supported by Pearson's correlations between the compounds and the activity and cited in literature (González & Nazareno, 2011;Vinholes et al, 2011).…”

Section: Hypochlorous Acid (Hocl)mentioning

confidence: 60%

Beverages of lemon juice and exotic noni and papaya with potential for anticholinergic effects

et al. 2015

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Section: Hypochlorous Acid (Hocl)mentioning

confidence: 60%

Beverages of lemon juice and exotic noni and papaya with potential for anticholinergic effects

et al. 2015

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“…The sample was monitored with UV detection at 280 nm at ambient temperature. Peak purity was checked by the software contrast facilities and the phenolic and flavonoid compounds were identified (Vinholes et al 2011).…”

Section: Hplc Analysismentioning

confidence: 99%

Maesa indica: a nutritional wild berry rich in polyphenols with special attention to radical scavenging and inhibition of key enzymes, α-amylase and α-glucosidase

et al. 2016

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The present study was aimed to evaluate the nutritional, antioxidant properties and inhibition of the key enzyme such as a-amylase and a-glucosidase from the fruits of Maesa indica. The results revealed that M. indica fruits possess an enormous amount of protein (45.68 mg/ g), carbohydrates (25.12 mg/g) and mineral elements. The acetone extract were capable of hunting radicals by providing electrons and break chain reaction, especially in ABTS Á? (3719.23 lmol TE/g extract), OH Á (66.50 %) and NO Á (81.50 %) radical scavenging assays. The methanol extract showed a strong inhibition towards a-amylase and a-glucosidase (IC 50 of 37.80 and 23.74 lg/mL, respectively). HPLC analysis enumerate that both extracts illustrates the presence of polyphenolic compounds namely quercetin, caffeic acid, rutin and chlorogenic acid.

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“…The anti-diabetic activity was determined by the alpha-glucosidase inhibition assay according to Vinholes et al (2011). Aliquots of raw and roasted pumpkin seed extracts (0.020 to 3.5 uL) were transferred in polypropylene test tubes and dried under a stream of nitrogen.…”

Section: In Vitro Anti-diabetic Activitymentioning

confidence: 99%

In vitro health beneficial activities of Pumpkin seeds from Cucurbita moschata cultivated in Lemnos

Sakka

Karantonis

2015

IJFS

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Pumpkin seeds are commonly consumed in Greece. Although Cucurbita moschata is locally grown in Lemnos and is traditionally used in pumpkin pies, the seeds are currently discarded after consumption of the fruit flesh. The aim of the present study was to investigate the nutritional functionality of pumpkin seeds from Cucurbita moschata grown in Lemnos. Cucurbita moschatas' seeds, raw or roasted, were appropriately extracted and the results are presented for raw versus (vs) roasted seed extracts. The phenolic content was expressed as µg gallic acid/g of seeds according to Folin-Ciocalteau assay (370.3 ± 19.1 vs 551.0 ± 22.0). Antioxidant capacity was expressed as equivalent amount for 50% scavenging in mg of seeds for DPPH (50.03 ± 5.91 vs 25.82 ± 6.77) and ABTS (17.85 ± 0.77 vs 12.77 ± 0.76) assays, and as µmol of trolox/g of seeds for FRAP (1.19 ± 0.05 vs 2.50 ± 0.23) and CUPRAC (2.13 ±0.11 vs 3.25 ± 0.06) assays. Anti-inflammatory/antithrombotic and anti-diabetic activities were expressed as mg of seeds for 50% inhibition of platelet activating factor (0.62 vs 0.15) and as µg of seeds for 25% inhibition of alpha-glycosidase (40.0 vs 61.0) activities respectively. Moreover, anti-atherogenic activity was expressed as the % increase in lag time of human plasma oxidation (62.7 versus 163.2) Raw and roasted pumpkin seed extracts exert anti-oxidant, anti-thrombotic/anti-inflammatory, antiatherogenic and antidiabetic activities. Cucurbita moschata seeds may represent a novel opportunity for development of functional foods, with a local interest in Lemnos that would contribute also to the regional public health improvement.

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In vitro studies to assess the antidiabetic, anti-cholinesterase and antioxidant potential of Spergularia rubra

Cited by 106 publications

References 33 publications

Beverages of lemon juice and exotic noni and papaya with potential for anticholinergic effects

Beverages of lemon juice and exotic noni and papaya with potential for anticholinergic effects

Maesa indica: a nutritional wild berry rich in polyphenols with special attention to radical scavenging and inhibition of key enzymes, α-amylase and α-glucosidase

In vitro health beneficial activities of Pumpkin seeds from Cucurbita moschata cultivated in Lemnos

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