The authors' rationale for conducting this study was that while there have been numerous clinical trials evaluating white spot lesions The aim of the study reviewed for this commentary was to evaluate one such alternative method, topical fluoride varnish, and its ability to revert white spot lesions (WSLs) after the debonding of orthodontic brackets. It has been shown that orthodontic patients have a significantly higher incidence of WSLs than patients who have not had orthodontic therapy, 2 and more recent investigations have put the incidence of WSLs during orthodontic treatment with fixed appliances at 73% to 95%. 3,4 Topical fluoride varnish has been demonstrated to reduce WSLs during orthodontic treatment, 5 so one could logically assume that the same effect could be achieved following orthodontic therapy.The purpose of this study was to discover whether or not topical fluoride varnish, when applied in those patients who have WSLs evident following debonding, would be a successful intervention and a preferential method of fluoride delivery. As a delivery mechanism, fluoride varnish applied topically, addresses the issue of patient compliance better than any other current application method and can be applied by auxiliary personnel during routine appointments. 6 The authors' study design was one in which 12-to 22-year old children, adolescents and young adults were blindly randomised to receive topical fluoride varnish or a placebo (saline) during the first six months following debonding. A unique aspect of this randomised, parallel group, controlled clinical trial was that the WSLs were evaluated by the use of laser fluorescence (Diagnodent Pen ® , KaVo, Inc.), which has been shown to have a high degree of reliability and validity at quantification of smooth surface lesions. 7,8 Even though this method of evaluation has been shown to be adversely influenced by a number of variables in the oral environment, 8 care was taken by the researchers to minimise these
SUMMARY TRIAL/CARIESDesign A randomised, parallel-group, controlled clinical trial.