In vitro effect of eugenol and cinnamaldehyde on membrane potential and respiratory chain complexes in isolated rat liver mitochondria

Bioactivity of flavonoid compounds from Poncirus trifoliata L. (Family: Rutaceae) against the dengue vector, Aedes aegypti L. (Diptera: Culicidae)

“…In comparison with the results of earlier studies, it was noticeable that flavonoid compounds tested in this study exerted promising mosquito larvicidal potential, which was greater than previously described isolated compounds. The mode of action of these flavonoid compounds on mosquito larvae are not known, but previous studies by Usta et al (2002) demonstrated that phytochemicals interfered with the proper functioning of mitochondria more specifically, at the proton transferring sites. The results of ovicidal activity obtained in this present work indicate that the target period of action by flavonoid compounds as an effective ovicide is the early stage of egg development, and also higher concentrations of flavonoid compounds cause maximum egg mortality.…”

Chemistry and Bioactivity of Essential Oils

“…The release of proteins from the mitochondrial membrane bilayer is known to play a crucial role in apoptosis, and permeabilization of the outer membrane can influence this [326]. Cinnamaldehyde has been shown to adversely influence several mitochondrial membrane functions [327] and may also exert its apoptotic effects in this manner.…”

Simultaneous Determination of Cinnamaldehyde, Eugenol and Paeonol in Traditional Chinese Medicinal Preparations by Capillary GC-FID

“…Determination of CNMD, EL and PL in herbal medicinal materials, pharmaceutical and biomedical samples mainly relies on chromatography techniques, especially HPLC [11][12][13][14][15][16][17][18][19] and GC, [20][21][22][23][24][25][26][27][28][29][30][31][32] and TLC is usually used to identify medicinal materials.…”