In-vitro antioxidant and anti-inflammatory activities of ethanol stem-bark extract of Blighia sapida K.D. Koenig

Adekola, Mukaila B.; Areola, J.O.; Fagbohun, Oladapo F.; Asaolu, F.T.; Ogundepo, Gbenga Emmanuel; Fajobi, A. O.; Babalola, O. O.

doi:10.1016/j.jpha.2021.04.002

Cited by 8 publications

(4 citation statements)

References 16 publications

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“…Extracts of Anabasis aretioides in studies by Sun and Shahrajabian (2023) [49] showed an antioxidant effect on the DPPH radical, and their activity was compared with various positive controls: the synthetic antioxidant BHA, ascorbic acid, and quercetin. The acetone extract showed the best free radical scavenging activity [50]. It is also reported that methanol and ethyl acetate extracts showed the same activity.…”

Section: Pharmacological Activitiesmentioning

confidence: 75%

Pharmacological Properties of Four Plant Species of the Genus Anabasis, Amaranthaceae

Shegebayev,

Turgumbayeva,

Datkhayev

et al. 2023

Molecules

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The genus Anabasis is a member of the family Amaranthaceae (former name: Chenopodiaceae) and includes approximately 102 genera and 1400 species. The genus Anabasis is one of the most significant families in salt marshes, semi-deserts, and other harsh environments. They are also renowned for their abundance in bioactive compounds, including sesquiterpenes, diterpenes, triterpenes, saponins, phenolic acids, flavonoids, and betalain pigments. Since ancient times, these plants have been used to treat various diseases of the gastrointestinal tract, diabetes, hypertension, and cardiovascular diseases and are used as an antirheumatic and diuretic. At the same time, the genus Anabasis is very rich in biologically active secondary metabolites that exhibit great pharmacological properties such as antioxidant, antibacterial, antiangiogenic, antiulcer, hypoglycemic, hepatoprotective, antidiabetic, etc. All of the listed pharmacological activities have been studied in practice by scientists from different countries and are presented in this review article to familiarize the entire scientific community with the results of these studies, as well as to explore the possibilities of using four plant species of the genus Anabasis as medicinal raw materials and developing medicines based on them.

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Section: Pharmacological Activitiesmentioning

confidence: 75%

Pharmacological Properties of Four Plant Species of the Genus Anabasis, Amaranthaceae

Shegebayev,

Turgumbayeva,

Datkhayev

et al. 2023

Molecules

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show abstract

“…DPPH is a stable free radical compound that exhibits a purple colour and possesses a distinct UV–vis absorption peak at 517 nm. This compound can be efficiently reduced by antioxidant substances, making it a suitable indicator for evaluating the in vitro radical scavenging potential [ 48 ]. As shown in Fig.…”

Section: Resultsmentioning

confidence: 99%

A multifunctional nanogel encapsulating layered double hydroxide for enhanced osteoarthritis treatment via protection of chondrocytes and ECM

Liu,

Sun,

et al. 2024

Materials Today Bio

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“…Inhibition of protein denaturation. The potential for inhibiting albumin denaturation was assessed according to the literature [82][83][84] . A reaction mixture (5 mL) containing 0.2 mL of BSA (Bovine serum albumin), 2.8 mL of PBS (pH 6.4), and 2 mL of determined concentrations of ChNPs (10, 50, 100, 500, 1000 mg/10 mL) were incubated for 15 min at 37 °C, then heated up to 70 °C for 5 min.…”

Section: In-vitro Anti-inflammatory Activitymentioning

confidence: 99%

Biological study of skin wound treated with Alginate/Carboxymethyl cellulose/chorion membrane, diopside nanoparticles, and Botox A

Mahheidari,

Kamalabadi-Farahani,

Nourani

et al. 2024

npj Regen Med

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A hydrogel-based wound dressing with desirable properties is necessary for achieving functional skin integrity post-injury. This study focuses on preparing a hydrogel using Alginate/Carboxymethyl cellulose (Alg/CMC) as a base material. To evaluate its regenerative effects on full-thickness wounds, diopside nanoparticles and Botulinum toxin A (BTX-A) were incorporated into the hydrogel along with chorion membrane. The diopside nanoparticles (DNPs) act as a proangiogenic factor, promoting proliferation and regulating inflammation, while the chorion membrane facilitates these processes. Additionally, BTX-A prevents scar formation and aids in wound closure. The nanoparticles and hydrogel were characterized using various techniques, and their cytocompatibility was assessed. In vivo studies and quantitative polymerase chain reaction analysis showed that wound area reduction was significant after two weeks of treatment with the Alg/CMC/ChNPs/DNPs/BTX-A hydrogel. Overall, this scaffold demonstrated potential for promoting tissue regeneration and new epithelization formation, making it a promising candidate for enhancing skin restoration in wound treatments.

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In-vitro antioxidant and anti-inflammatory activities of ethanol stem-bark extract of Blighia sapida K.D. Koenig

Cited by 8 publications

References 16 publications

Pharmacological Properties of Four Plant Species of the Genus Anabasis, Amaranthaceae

Pharmacological Properties of Four Plant Species of the Genus Anabasis, Amaranthaceae

A multifunctional nanogel encapsulating layered double hydroxide for enhanced osteoarthritis treatment via protection of chondrocytes and ECM

Biological study of skin wound treated with Alginate/Carboxymethyl cellulose/chorion membrane, diopside nanoparticles, and Botox A

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