Impact of Short and Moderate Rest Intervals on the Acute Immunometabolic Response to Exhaustive Strength Exercise

Abstract

The purpose of this study was to verify the influence of the short and moderate intervals of recovery in response to an acute bout of exhaustive strength exercise on performance, inflammatory, and metabolic responses in healthy adults. Eight healthy subjects (age = 24.6 ± 4.1 years) performed 2 randomized sequences: short = 70% of 1 repetition maximum (1RM) with 30 seconds of rest between sets; moderate = 70% of 1RM with 90 seconds of rest between sets. All sequences of exercises were performed over 4 sets until movement failure in the squat and bench press exercises, respectively. The total number of repetitions performed was recorded for each set of each exercise for all sequences. The percentages of fat mass and fat-free mass were estimated by dual-energy x-ray absorptiometry. Glucose, tumor necrosis factor-α, interleukin (IL)-6, IL-10, and nonester fatty acid were assessed, at baseline, immediately after exercise, after 15 and 30 minutes. When compared with the maximum number of repetitions and the total weight lifted, there was a statistically significant decrease after both intervals. The only statistically significant decreases over time occurred at the post-15 minutes assessment of the IL-6 and glucose when a moderate interval of recovery was performed. When comparing the alterations between the pools (the mean of the cluster of all periods in each variable), there was a statistically significant increase on the IL-6 and IL-10 when a moderate interval of recovery was performed again, however, not considering a statistical difference on the IL-10. Thus, we concluded that different interval of recovery in response to exhaustive strength exercise decreases performance but in only moderate intervals, it is associated with inflammatory and metabolic response.

Immunometabolic Responses after Short and Moderate Rest Intervals to Strength Exercise with and without Similar Total Volume

“…In contrast, while there were significant main effects for time in the present study, there were no differences between groups for IL-10, IL1-ra, and MCP-1 response. The differences in training status and/or workload during the strength exercise sessions may explain the discrepancy in results between the present and previous studies as subjects in Heavens et al (2014), and Rossi et al (2016) were resistance trained while the subjects in the present study were not.…”

“…Phillips et al (2010) reported greater post exercise IL-6 concentrations following moderate intensity (65% 1 RM) training with 2 min of rest compared to higher intensity (85% 1 RM) training with 2 min rest. We recently compared the effects of 30- and 90-s of rest between 4 sets of squat and bench press with 70% 1 RM to failure in resistance trained men and reported greater post exercise IL-6 concentrations following the 90-s condition (Rossi et al, 2016). …”

“…Phillips et al (2010) reported greater post-exercise IL-6 concentrations with 65% 1 RM compared to 85% 1 RM and 2 min recovery intervals. Our group recently (Rossi et al, 2016) investigated the differences between short (30 s) and moderate (90 s) intervals of recovery during an acute bout of exhaustive strength exercise with 4 sets of 70% of 1 RM in squat and bench press. The volume load performed was significantly greater (~27%) in the moderate rest condition and IL-6 increased only in the moderate rest condition.…”

“…The results of Rossi et al (2016) and Phillips et al (2010) suggest that longer recovery intervals and higher total volume load contributes to resistance exercise induced IL-6, however, the effect of different recovery intervals with similar volumes on the acute inflammatory response is unknown. Therefore, the aim of this study was to investigate the influence of short (30 s) and moderate (90 s) intervals of recovery during an acute bout of exhaustive strength exercise on performance, metabolic, hormonal, and inflammatory responses with and without matched total volume loads in healthy adults.…”

Immunometabolism and Exercise: New avenues

“…Em relação ao intervalo de recuperação, nosso grupo verificou a influência de 30 e 90 segundos de intervalo em jovens saudáveis submetidos a 4 séries de agachamento seguido por 4 séries de supino horizontal, com 70% de 1RM até a falha do movimento; concluímos que apesar do desempenho diminuir em ambos os intervalos, somente o tempo de 90 segundos induziu aumento nas concentrações de IL-6 e redução de IL-10, porém sem significância estatística nessa última, assim, intervalos moderados de recuperação poderiam favorecer uma maior resposta metabólica e benefícios antiinflamatórios durante o processo de reparação tecidual (Rossi, Gerosa-Neto, Zanchi, Cholewa, & Lira, 2016).…”