Impact of Phyto-Cocci® Powder Supplementation on Broiler Growth Performance, Eimeria Oocyst Shedding and Gut Health

Abdelhady, A. Y.M.; Abdullah, Seerwan; El-Safty, S. A.; Eldeib, M.; Hashim, Mosaad

doi:10.3923/ijps.2020.66.74

Cited by 2 publications

(1 citation statement)

References 19 publications

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“…Coccidiosis is a very fatal protozoal disease characterized by bloody droppings, intestinal inflammation, poor growth performance, increased morbidity and mortality 3 . Coccidiosis affects nutrient digestibility by reducing the size of villi in the small intestine 4 , and alters the expression of genes regulating transport proteins and digestive enzymes of the small intestine 5 , 6 . In coccidiosis, there is increased production of reactive oxygen species (ROS) and nitrogenous species responsible for lower production of antioxidant enzymes including superoxide dismutase and catalase 7 .…”

Section: Introductionmentioning

confidence: 99%

Biosynthesis and characterization of zinc oxide nanoparticles using Nigella sativa against coccidiosis in commercial poultry

Lail

Sattar

Omer

et al. 2023

Sci Rep

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Coccidiosis causes huge economic losses worldwide. Current study evaluated the effect of biosynthesized Zinc oxide nanoparticles (ZnONPs) using Nigella sativa, on Eimeria tenella infected broilers. Scanning electron microscopy showed spherical ZnONPs with 50–100 nm diameter, Fourier transforms infrared spectroscopy revealed the functional groups involved in the reduction of zinc acetate dihydrate to ZnONPs, UV–vis spectroscopy showed a peak at 354 nm, and Zeta potential exhibited stability at − 30 mV. A total of 150, a day-old broiler chicks were divided into 5 equal groups. Control negative: uninfected and untreated; Control positive: Infected and untreated; 3rd, 4th and 5th group were infected orally with 5 × 104 sporulated oocysts of Eimeria tenella and treated with 60 mg/kg ZnONPs, 1% Nigella sativa seeds and amprolium 125 ppm, respectively. ZnONPs significantly (p < 0.05) improved the growth performance in the infected birds and decreased the oocyst shedding and anti-coccidial index. A significant (p < 0.05) decrease in the level of aspartate transferase and alanine transferase, whereas, a significantly higher amount of antioxidants like catalase and superoxide dismutase in ZnONPs treated group was observed. Pro-inflammatory cytokines like IL-2 and TNF-α were significantly decreased by ZnONPs (p < 0.05). In conclusion, biogenic ZnONPs with Nigella sativa might have enhanced anticoccidial, antioxidant, and anti-inflammatory effects with improved growth performance.

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