Immediate Loading of Brånemark System® TiUnite™ and Machined‐Surface Implants in the Posterior Mandible: A Randomized Open‐Ended Clinical Trial

Rocci, Antonio; Martignoni, M.; Gottlow, Jan

doi:10.1111/j.1708-8208.2003.tb00016.x

Cited by 230 publications

(216 citation statements)

References 5 publications

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“…The reverse torque removal values are directly related to the contact bone/ implant interface, bone density, quantity of cortical bone around the torque after certain periods. There was no significant differences between the torques induced by machined and anodized surfaces of test groups in the present experiment, which is in agreement with others reports [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] . Likewise, no difference was observed in the control groups.…”

Section: ■ Discussionsupporting

confidence: 83%

“…According to Zhu et al 10 modified surfaces improve biocompatibility, increase cellular adhesion and proliferation. Studies by Rocci et al 5 and Bahat 11 have indicated that modifications of the surface and macro design of the implant are particularly important for its longevity.…”

Section: IImentioning

confidence: 99%

“…It has been also demonstrated that nicotine may have beneficial anti-inflammatory effects, which may reduce the symptoms of other systemic inflammatory diseases, such as ulcerative colitis 4 . One possible solution to smoker patients could be changing the dental implant surface, in order to enhance bone response and thus, improve the clinical success rate, The use of implants with microtopography changed surface could benefit patients with risk factors such as smoking [5][6] . Results of clinical studies with short-length and machined-polished dental implants (Branemark ® Type) showed that failure rates were higher, particularly when the implants were inserted into trabecular bone 7 .…”

Section: ■ Introductionmentioning

confidence: 99%

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The effects of subcutaneous injection of nicotine on osseointegration of machined and anodized implants in rabbits

Linden

Bittencourt²,

Carli³

et al. 2018

Acta Cir. Bras.

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Purpose: To evaluate the influence of subcutaneous injection nicotine in osseointegration process on different implant surfaces. Methods: Twenty-two male rabbits were distributed into two groups according to the subcutaneous injections: (1) nicotine 3 mg/day/kg and (2) 0.9 % NaCI 3 mL/day/kg, three times a day; subgroups were then designated-machined and anodized implants were placed in the right and left tibia bones, respectively. The animals were submitted euthanasia after periods of eight weeks to determine nicotine and cotinine levels, alkaline phosphatase and biomechanical analysis. Results: The plasmatic levels of nicotine and cotinine were 0.5 ± 0.28 ng/mL and 9.5 ± 6.51 ng/mL, respectively. The alkaline phosphatase analyses in blood levels in control group were observed 40.8 ± 11.88 UI/L and 40.75 ± 12.46 UI/L, for the surfaces machined and anodized, respectively. In the test group was observed levels 37.9 ± 4.84 UI/L, for both implant surfaces. No significant differences were observed between control and test groups and between the implant surfaces regarding alkaline phosphatase blood levels. For biomechanics, no significant differences were observed in control group between the machined (25±8.46 Ncm) or anodized (31.2 ± 6.76 Ncm) implants. However, the treatment with nicotine induced higher torque than control in both machined (38.3 ± 13.52 Ncm) and anodized (35.5 ± 14.17 Ncm) implants, with p = 0.0024 and p = 0.0121, respectively. Conclusion: Subcutaneous injection of nicotine following implant insertion didn't have effect on osseointegration, independently from the implant surface.

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Section: ■ Discussionsupporting

confidence: 83%

Section: IImentioning

confidence: 99%

Section: ■ Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The effects of subcutaneous injection of nicotine on osseointegration of machined and anodized implants in rabbits

Linden

Bittencourt²,

Carli³

et al. 2018

Acta Cir. Bras.

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“…Surfaces on TiUnite®, TiXos® and sand-blasted implants are three typical types of implant surfaces that were investigated in this work. The fact that these implants can promote osseointegration at different levels has already been an indisputable fact [14][15][16]26,27]. By using conventional evaluation methods, e.g., histomorphometrical evaluations, removal torque tests, and success and failure criteria, a series of parameters such as BIC, removal torque and implant survival rate can be revealed.…”

Section: Discussionmentioning

confidence: 99%

“…Although the sample prepared by argon ion beam cross section polishing is not suitable for TEM observation, it fits well for SEM observation to reveal the bone formation mechanisms. Furthermore, the functional mechanism of the surfaces of TiUnite®, TiXos® and sand-blasted implants during osseointegration can be elucidated, which is different from the other clinical evaluation or comparative trial of the implants with turn machined surface [14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Microscopic view of osseointegration and functional mechanisms of implant surfaces

Han

Shen

2015

Materials Science and Engineering: C

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Argon ion beam polishing technique was applied to prepare the cross sections of implants feasible for high resolution scanning electron microscope investigation. The interfacial microstructure between newly formed bone and implants with three modified surfaces retrieved after in vivo test using three different animal models was characterized. By this approach it has become possible to directly observe early bone formation, the increase of bone density, and the evolution of bone structure. The two bone growth mechanisms, distant osteogenesis and contact osteogenesis, can also be distinguished. These direct observations give, at microscopic level, a better view of osseointegration and expound the functional mechanisms of various implant surfaces for osseointegration.

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Interventions for replacing missing teeth: different types of dental implants

Esposito¹,

Coulthard²,

Thomsen³

et al. 2005

Cochrane Database of Systematic Reviews

156

163

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Based on the available results of RCTs, there is limited evidence showing that implants with relatively smooth (turned) surfaces are less prone to loose bone due to chronic infection (perimplantitis) than implants with rougher surfaces. On the other hand, there is no evidence showing that any particular type of dental implant has superior long-term success. These findings are based on a few RCTs, often at high risk of bias, with few participants and relatively short follow-up periods. More RCTs should be conducted, with follow up of at least 5 years including a sufficient number of patients to detect a true difference if any exists. Such trials should be reported according to the CONSORT recommendations (http://www.consort-statement.org/).

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Immediate Loading of Brånemark System® TiUnite™ and Machined‐Surface Implants in the Posterior Mandible: A Randomized Open‐Ended Clinical Trial

Cited by 230 publications

References 5 publications

The effects of subcutaneous injection of nicotine on osseointegration of machined and anodized implants in rabbits

The effects of subcutaneous injection of nicotine on osseointegration of machined and anodized implants in rabbits

Microscopic view of osseointegration and functional mechanisms of implant surfaces

Interventions for replacing missing teeth: different types of dental implants

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