“…Fusarium species are opportunistic pathogens that cause locally invasive cellulitis and disseminated infection in an immunocompromised patient 6 . However, Fusarium onychomycosis usually occurs in healthy individuals in the absence of trauma or dystrophic abnormalities.…”
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“…Fusarium species are opportunistic pathogens that cause locally invasive cellulitis and disseminated infection in an immunocompromised patient 6 . However, Fusarium onychomycosis usually occurs in healthy individuals in the absence of trauma or dystrophic abnormalities.…”
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
The patient was a 73-year-old healthy female farmer who had been treated with terbinafine for 25.5 months by a primary physician. She exhibited a discoloration and thickening of the right big toenail. She had no concomitant paronychia. Direct microscopy revealed chlamydoconidia and hyphae, and periodic acid-Schiff stained nail specimen showed septate hyphae. On the basis of these morphological features and gene analysis, the final diagnosis was ungual hyalohyphomycosis caused by Fusarium proliferatum. Topical application of 10% efinaconazole solution cured the disease in 10 months.
Hyalohyphomycosis are opportunistic fungal infections caused by fungi with colorless septate hyphae.
Fusarium
is a hyalohyphomycetes which can cause localized or disseminated infections depending on host immunity. Our patient had an infectious lesion over the coronary artery bypass grafting (CABG) scar which was not responding to antibacterial treatment. Further investigations revealed it to be localized cutaneous
Fusarium
infection. The patient was treated with fluconazole 3 mg/kg/day for 3 weeks and responded very well without any recurrence during the next 3 months follow-up. Thus, this case highlights the effectiveness of fluconazole in uncommon fungal infection.
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