Human Papillomavirus‐16 Prevalence in Gingival Tissue and Its Association With Periodontal Destruction: A Case‐Control Study

Abstract

In the population studied, HPV-16 may not have participated in the pathogenesis of chronic periodontitis, and the gingival tissue did not act as a reservoir for this virus.

Prevalence of oral and oropharyngeal human papillomavirus infection in Brazilian population studies: a systematic review

“…This rate was slightly higher than that observed in a systematic review that included data from 1997 to 2009 (4.5%; 95% CI 3.9---5.1). 63 7 Mean of 23 y 3.0% 3.0% 40/60 Horewicz (2010) 8 Mean of 38 y 3.8% ---28/76 Tristão (2012) 9 Predominantly between 18 and 21 y ------37/88…”

“…Lira (2010) 25 Mean of 65 y ------49/26 Oliveira (2008) 26 Mean of 59 y 81.6% ---73/14 Simonato (2008) 27 79.3% under 60 y 89.7% 62.1% 27/2 Soares (2008) 28 Mean of 65 y ---------Oliveira (2009) 29 59% over 60 y ------57/31 Pereira (2011) 30 Mean of 63 y ------19/8 Spindula-Filho (2011) 31 55.3% over 65 y 72.3% 61.7% 34/13 Cordeiro-Silva (2012) 32 44.5% over 58 y 80.0% 68.9% 35/10 Kaminagakura (2012) 33 Mean of 51 y 84.0% 62.0% 81/33 Marques-Silva (2012) 34 33 38 Mean of 45 y ------21/43 Ribeiro (2014) 39 Mean of 32 y 27.4% ---31/31 Vidotti (2014) 40 42 Mean of 29 y ------30/0 Peixoto (2011) 43 Mean of 37 70 3 (4.3%) ---------Sacramento (2006) 6 50 7 (14.0%) 1 (2.0%) 1 (2.0%) 2 (4.0%) Silva (2007) 16 10 1 (10.0%) ---------Esquenazi (2010) 7 100 0 (0.0%) ---------Horewicz (2010) 8 104 0 (0.0%) 0 (0.0%) ------Araujo (2011) 45 16 1 (6.2%) 0 (0.0%) 0 (0.0%) 0 (0.0%) Betiol (2012) 13 22 16 16 (100.0%) ---------Mazon (2011) 17 18 6 (33.0%) 0 (0.0%) 0 (0.0%) 0 (0.0%) Fregonezi (2012) 23 Oral/oropharyngeal HPV infection in patients with oral or oropharyngeal SCC Miguel (1998) 24 28 4 (14.3%) ---------Soares (2002) 18 10 0 (0.0%) ---------Soares (2003) 19 27 13 (48.1%) ------10 (37.0%) Fregonesi (2003) 20 17 6 (35.3%) ------5 (29.0%) Cortezzi (2004) 15 16 4 (25.0%) 4 (25.0%) ------Silva (2007) 16 50 37 (74.0%) ---------Soares (2007) 27 29 5 (17.2%) --------...…”

Prevalence of human papilloma virus in marginal periodontium and its association with periodontitis: A cross sectional study

“…had conducted a cross-sectional study in which gingival tissue sample showed a prevalence of 26%. [6] Till now the prevalence studies were carried out mostly on foreign population which included United States,[16] Argentina,[17] France,[7] Brazil[18] and Finland[6] and prevalence varied from 0% to 92.31%. There are no published studies on the prevalence of HPV in periodontal tissues of Indian Population.…”

“…The results were in consistence with the study by Horewicks et al ., in which negative results were obtained when tested for HPV-16 in periodontal tissue. [18] This emphasizes the fact that this particular type of HPV may be absent from marginal periodontium in a systemically healthy patient even if the patient has periodontitis. HPV-16 is a high risk virus which may be present only in tissues that had undergone carcinogenic transformation.…”

HPV and oral lesions: preventive possibilities, vaccines and early diagnosis of malignant lesions

“…Genital infection with HPV can be transmitted to oral mucosa through autoinoculation, oral sex, or oral contact. The virion is composed of a double-stranded, circular, 8,000-base pair DNA genome encased in a naked icosahedral capsid about 55 nm in diameter that comprise a heterogeneous family consisting of more than 130 different HPV types and 16 categories (10)(11)(12)(13).…”