Human chromosomal polymorphism

Abstract

Chromosomal Q polymorphism was studied in 157 adolescents of Yakut nationality (67 males and 90 females) living in Eastern Siberia, on the territory of the Yakut ASSR. Of the 157 subjects, 123 had chromosomal Q variants while 34 (21.7%) had no Q-heterochromatin bands with fluorescence levels 4 and 5. The mean number of Q variants per individual ranged from 0 to 5, with a mean of 1.64. No differences were observed in the frequency of Q variants between sexes. The observed homo- and heteromorph frequencies always agreed with those predicted by the law of Hardy-Weinberg. Of the 157 subjects, four (2.55%) had pericentric inversion of the Q-heterochromatin band in chromosome 3. The following topics are discussed: possible selective value of chromosomal Q-heterochromatin material in the adaptation of human populations to extreme environmental factors, in particular to cold; the taxonomic value of chromosomal Q polymorphism in ethnic anthropology.

Transferrin Subtypes in Some Eurasian and African Populations

“…In the course of long-term studies on chromosomal polymorphisms in human populations living under dif ferent climato-geographic conditions in Eurasia and Africa, \vc collected serum samples and kept them in liquid nitrogen at -196 °C [8][9][10][11][12][13]. Detailed descriptions of ethnic, sex-and age-related features, and the loca tions of the populations have been presented previ ously .…”