Hochaktive antiretrovirale Therapie bei Neuro-AIDS

Husstedt, Ingo W.; Reichelt, D.; Neuen-Jakob, E.; Hahn, Katrin; Kästner, F.; Einsiedel, Regina von; Vielhaber, B.; Arendt, Gabriele; Evers, Stefan

doi:10.1007/s00115-009-2684-6

Cited by 6 publications

(1 citation statement)

References 41 publications

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“…Compared with traditional single antiviral drug, HARRT combines different categories’ antiviral chemicals and prolongs the HIV/AIDS patient survival (~7–10 years; Lu et al, 2018 ). Nevertheless, the complexity of regimens, high economic cost and frequent side effects (e.g., gastrointestinal reactions depression, insomnia, headaches) make HAART particularly difficult to insist ( Trotta et al, 2002 ; Husstedt et al, 2009 ; Endalamaw et al, 2018 ). Cruess et al (2012) demonstrated depressive symptoms were associated with nonadherence of antiretroviral and psychotropic medication ( Cruess et al, 2012 ).…”

Section: Discussionmentioning

confidence: 99%

Global trends in depression among patients living with HIV: A bibliometric analysis

Zhang

Hao

et al. 2023

Front. Psychol.

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BackgroundHuman immunodeficiency virus (HIV) related depression has seriously affected the quality of life and treatment outcomes of patients living with HIV (PLWH), which has become a hot topic in recent years. This study aims to discover the main keywords, predict frontier topics, and give meaningful suggestions for researchers by bibliometric analysis.MethodsPublications between 1999 and 2022 on depression in HIV/AIDS were searched in the Web of Science core collection. Microsoft Excel 2010 and VOSviewer were utilized to key contributors (e.g., authors, journals, institutions, and countries). VOSviewer and CiteSpace were used to analyze the knowledge evolution, collaborative maps, hot topics, and keywords trends in this field.ResultsIn total, 8,190 publications were included in the final analysis. From 1999 to 2021, the number of published articles roughly presents a steadily increasing trend. The United States, South Africa, and the United Kingdom were three key contributing countries/regions to this field. University Calif San Francisco (United States), University Calif Los Angeles (United States), and Johns Hopkins University (United States) were three key contributing institutions. Safren, Steven A. was the most productive and highest cited author. AIDS Care was the top prolific journal. Antiretroviral therapy and adherence, men has sex with men, mental health, substance abuse, stigma, and Sub-Saharan Africa were the central topics regarding the depression-related research in HIV/AIDS.ConclusionThis bibliometric analysis reported the publication trend, major contributing countries/regions, institutions, authors, journals and mapped the knowledge network of depression-related research on HIV/AIDS. In this field, topics such as “adherence,” “mental health,” “substance abuse,” “stigma,” “men who have sex with men” and “South Africa” have attracted considerable attention.

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Section: Discussionmentioning

confidence: 99%

Global trends in depression among patients living with HIV: A bibliometric analysis

Zhang

Hao

et al. 2023

Front. Psychol.

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Current awareness: Pharmacoepidemiology and drug safety

2010

Pharmacoepidemiology and Drug

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In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of pharmacoepidemiology and drug safety. Each bibliography is divided into 23 sections: 1 Reviews; 2 General; 3 Anti‐infective Agents; 4 Cardiovascular System Agents; 5 CNS Depressive Agents; 6 Non‐steroidal Anti‐inflammatory Agents; 7 CNS Agents; 8 Anti‐neoplastic Agents; 9 Haematological Agents; 10 Neuroregulator‐Blocking Agents; 11 Dermatological Agents; 12 Immunosuppressive Agents; 13 Autonomic Agents; 14 Respiratory System Agents; 15 Neuromuscular Agents; 16 Reproductive System Agents; 17 Gastrointestinal System Agents; 18 Anti‐inflammatory Agents ‐ Steroidal; 19 Teratogens/fetal exposure; 20 Antidiabetic Agents; 21 Contrast Agents; 22 Bone Conservation Agents; 23 Others. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted.

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Animal Models for Depression Associated with HIV-1 Infection

Barreto

Viegas

Ziff

et al. 2013

J Neuroimmune Pharmacol

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Antiretroviral therapy has greatly extended the lifespan of people living with human immunodeficiency virus (PLHIV). As a result, the long-term effects of HIV infection, in particular those originating in the central nervous system (CNS), such as HIV associated depression, have gained importance. Animal models for HIV infection have proved very useful for understanding the disease and developing treatment strategies. However, HIV associated depression remains poorly understood and so far there is neither a fully satisfactory animal model, nor a pathophysiologically guided treatment for this condition. Here we review the neuroimmunological, neuroendocrine, neurotoxic and neurodegenerative basis for HIV depression and discuss strategies for employing HIV animal models, in particular humanized mice which are susceptible to HIV infection, for the study of HIV depression.

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Hochaktive antiretrovirale Therapie bei Neuro-AIDS

Cited by 6 publications

References 41 publications

Global trends in depression among patients living with HIV: A bibliometric analysis

Global trends in depression among patients living with HIV: A bibliometric analysis

Current awareness: Pharmacoepidemiology and drug safety

Animal Models for Depression Associated with HIV-1 Infection

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