Histopathological evaluation of endometrial biopsies and curetting’s in abnormal uterine bleeding

Vani, B. S.; Vani, R.; P., Jijiya Bai

doi:10.17511/jopm.2019.i04.02

Cited by 9 publications

(19 citation statements)

References 7 publications

(21 reference statements)

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“…In [5,9,11,12]. Hence, while evaluating the endometrial biopsy of patients in this age group presenting with abnormal uterine bleeding, details of the gravindex test for pregnancy should always be checked.…”

Section: Chief Complaints In Patientsmentioning

confidence: 99%

A Histopathological Study of Endometrial Biopsy Samples in Abnormal Uterine Bleeding

Vijayaraghavan¹,

Jadhav²,

Pradeep³

et al. 2022

Cureus

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Background: Abnormal uterine bleeding (AUB) is the most common health issue in women, defined as any bleeding pattern that differs in frequency, duration, and amount. Endometrial sampling and its histopathological examination is the first-line test in patients presenting with AUB. The aim of this study was to analyze the histopathological patterns of endometrium in women with AUB and to find the predominant histopathologic pattern in the different age groups of women with AUB.

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Section: Chief Complaints In Patientsmentioning

confidence: 99%

A Histopathological Study of Endometrial Biopsy Samples in Abnormal Uterine Bleeding

Vijayaraghavan¹,

Jadhav²,

Pradeep³

et al. 2022

Cureus

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“…Owing to the impact of various hormonal, dietary, and environmental factors on the endometrium, it is susceptible to multiple pathological lesions [3]. Abnormal uterine bleeding (AUB) is a pattern that does not correspond to the amount, duration, or frequency of a normal menstrual cycle [4,5]. According to reproductive function and age, the clinical presentation and mechanism of AUB and endometrial pathology vary with age [4].…”

Section: Discussionmentioning

confidence: 99%

Endometrial Patterns Among Rural Women Undergoing Gynecological Procedures in a Tertiary Care Hospital

Vijayakumar¹

2023

Cureus

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IntroductionWomen with endometrial diseases often present in outpatient departments, and outpatient procedures easily enable diagnosis. Histopathological patterns vary with age, menstrual cycle, drug use, and pathological state. Teaching hospitals are often located away from rural areas. Materials and methodsAn ambispective study was performed over 33 months in a rural medical college hospital by perusing the histopathological registers of the department. Details of history and endometrial samples (biopsy and hysterectomy) were obtained using biopsy numbers and requisition forms. Functional and organic histopathology findings were manually entered into a spreadsheet, and statistics were performed using Statistical Package for the Social Sciences (SPSS) for Windows version 22 (IBM SPSS Statistics, Armonk, NY, USA). ResultsThere were 226 women, with total abdominal hysterectomies (TAH) performed in a significantly higher proportion of middle-aged women (range: 41-59 years). Of the middle-aged women, 70% presented with excessive menstrual bleeding, and a similar percentage of older women presented with uterovaginal (UV) prolapse. Hysterectomy specimens constituted most samples in this study. Proliferative endometrium was observed in 40% of patients and metaplasia (papillary syncytial, tubal, and squamous) in only 1.7%. Normal proliferative and secretory endometrium were observed in 91 (40.3%) and 41 (18.1%) patients, respectively. The presence of hyperplasia, decidualization, stromal breakdown, adenocarcinoma, adenomyosis, and endometrial polyps did not vary significantly among the three age groups (elderly, middle-aged, and young). ConclusionMost women in rural areas presented to the gynecologist with uterine bleeding; middle-aged women constituted most of those with gynecological complaints. Normal endometrium was observed in nearly half of the patients. Adenomyosis was the most common cause of uterine bleeding. Uterine endometrial malignancies were rare.

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“…Data were entered in Microsoft excel and analysis was done in the form of percentages and proportions and it were represented in tables. [12][13][14][15] In this study, the endometrial histopathological pattern was determined by considering age of the patient, date of onset of last menstrual period, length of menstrual cycle and iatrogenic use of hormones. 18,19…”

Section: Discussionmentioning

confidence: 99%

“…4 The cause of AUB varies according to the age, endometrial response to hormones and its variations and other structural lesions. 5 The FIGO has classified the causes for AUB into 2 group: structural/organic and non-structural/non organic. The PALM-COEIN system is etio-pathogenesis based, with PALM describing structural causes and COEIN denoting non-structural causes of AUB (Table 1).…”

Section: Introductionmentioning

confidence: 99%

“…6,7 Dysfunctional uterine bleeding (DUB) is present in 50% of the women with AUB that includes abnormal bleeding due to nonorganic causes. 5 and diagnostic accuracy. 9 Endometrial curettages exhibit a wide range of histopathological patterns due to normal and abnormal cyclical changes, drugs, hormones, infections, metabolic disease and malignancies.…”

Section: Introductionmentioning

confidence: 99%

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Histopathological evaluation of endometrial curettage in cases of abnormal uterine bleeding and its correlation with age of patient

Tilva

Jethwani

Dhruva

2022

Int J Reprod Contracept Obstet Gynecol

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Background: Abnormal uterine bleeding (AUB) is defined as a pattern of bleeding that does not correspond with the duration, amount and frequency of the flow of a normal menstrual cycle. The cause of AUB varies according to the age, endometrial response to hormones and its variations and other structural lesions. Endometrial sampling by endometrium curettage is safe and easy technique and its histopathological analysis is considered the gold standard for diagnosis of the etiology of AUB. Aims and objective was to evaluate the spectrum of endometrial histology in cases of AUB, to find out age wise incidence of AUB, and to find out age wise incidence of various histological pattern of endometrium in AUB.Methods: An observational study was conducted on dilatation and curettage material which were obtained from 110 women with a complaint of AUB attending the gynecology outpatient department (OPD) at tertiary care hospital, Rajkot, Gujarat during one year (August 2020 to July 2021).Results: Maximum number of cases of AUB were noted in the age group of (31-40) years (44 cases, 40%). Most common observed histopathological pattern in this study was normal cyclical patterns including proliferative endometrium (34.5%) and secretory endometrium (21%).Conclusions: Histopathological evaluation of endometrium is indicated in women over the age of 35 years presenting with AUB to rule out preneoplastic lesions and malignancies.

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Histopathological evaluation of endometrial biopsies and curetting’s in abnormal uterine bleeding

Cited by 9 publications

References 7 publications

A Histopathological Study of Endometrial Biopsy Samples in Abnormal Uterine Bleeding

A Histopathological Study of Endometrial Biopsy Samples in Abnormal Uterine Bleeding

Endometrial Patterns Among Rural Women Undergoing Gynecological Procedures in a Tertiary Care Hospital

Histopathological evaluation of endometrial curettage in cases of abnormal uterine bleeding and its correlation with age of patient

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