High ecological and human health risks from microcystins in vegetable fields in southern China

Xiang, Lei; Li, Yanwen; Liu, Bailin; Zhao, Hai-Ming; Li, Hui; Cai, Quan-Ying; Chen, Mo; Wong, Ming Hung; Li, Qing X.

doi:10.1016/j.envint.2019.105142

Cited by 80 publications

(64 citation statements)

References 46 publications

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“…Interestingly contents of vitamin C, soluble sugar and organic acid in fruits of cucumber at seedling stage were declined [64]. It is of interest that irrigation waters containing MCs (MC-LR, MC-RR, and MC-YR) collected from southern China regions were the major source of MCs accumulation in soils and vegetables, and majority of the vegetables exhibited moderate or high human health risk through diet [65]. The findings imply irrigation with MCs contaminated water is capable of threatening plant growth and human health.…”

Section: Toxicity and Carcinogenicitymentioning

confidence: 99%

A Mini Review on Microcystins and Bacterial Degradation

Massey

Yang

2020

Toxins

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Microcystins (MCs) classified as hepatotoxic and carcinogenic are the most commonly reported cyanobacterial toxins found in the environment. Microcystis sp. possessing a series of MC synthesis genes (mcyA-mcyJ) are well documented for their excessive abundance, numerous bloom occurrences and MC producing capacity. About 246 variants of MC which exert severe animal and human health hazards through the inhibition of protein phosphatases (PP1 and PP2A) have been characterized. To minimize and prevent MC health consequences, the World Health Organization proposed 1 µg/L MC guidelines for safe drinking water quality. Further the utilization of bacteria that represent a promising biological treatment approach to degrade and remove MC from water bodies without harming the environment has gained global attention. Thus the present review described toxic effects and bacterial degradation of MCs.

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Section: Toxicity and Carcinogenicitymentioning

confidence: 99%

A Mini Review on Microcystins and Bacterial Degradation

Massey

Yang

2020

Toxins

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“…Concentrations of MCs in waters are normally lower than 100 μg/L, but sometimes could be up to thousands of microgramme per litre, relying on environmental conditions and occurrence of MCs-producing cyanobacteria [ 8 , 12 ]. MCs in water can enter agricultural soils and show relatively high stability, because their cyclical heptapeptide structure is resistant to non-specific enzyme degradation, pH changes, and high temperature [ 13 , 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

“…MCs in water can enter agricultural soils and show relatively high stability, because their cyclical heptapeptide structure is resistant to non-specific enzyme degradation, pH changes, and high temperature [ 13 , 14 , 15 ]. There is thus a great possibility that agricultural soils in the regions with frequent CBs outbreaks can be heavily polluted by MCs [ 12 , 16 , 17 ]. Our recent field study showed that MCs were commonly detected in agricultural soils affected by CBs in southern China, with average concentrations in the range of 3.4–15.6 μg/kg and maximum concentration up to 186.3 μg/kg [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

“…There is thus a great possibility that agricultural soils in the regions with frequent CBs outbreaks can be heavily polluted by MCs [ 12 , 16 , 17 ]. Our recent field study showed that MCs were commonly detected in agricultural soils affected by CBs in southern China, with average concentrations in the range of 3.4–15.6 μg/kg and maximum concentration up to 186.3 μg/kg [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

“…MCs in soils can result in severely negative impacts on crops at perspectives of histology, cytology, and morphology, thus decreasing their growth and yield [ 7 , 18 , 19 ]. MCs are bioaccumulative in crops, posing a time- and concentration-dependent mode and raising a great concern on human health risks via the food chain [ 12 , 17 , 20 ]. Concentrations of MCs in edible parts of vegetables planted in the CBs-affected agricultural soils could be up to 382 μg/kg (fresh weight), with more than 60% of the vegetables exhibiting moderate or high human health risk via intake [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

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Bioaccumulation and Phytotoxicity and Human Health Risk from Microcystin-LR under Various Treatments: A Pot Study

Xiang

Wang

et al. 2020

Toxins

Self Cite

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Microcystin-LR (MC-LR) is prevalent in water and can be translocated into soil-crop ecosystem via irrigation, overflow (pollution accident), and cyanobacterial manure applications, threatening agricultural production and human health. However, the effects of various input pathways on the bioaccumulation and toxicity of MCs in terrestrial plants have been hardly reported so far. In the present study, pot experiments were performed to compare the bioaccumulation, toxicity, and health risk of MC-LR as well as its degradation in soils among various treatments with the same total amount of added MC-LR (150 μg/kg). The treatments included irrigation with polluted water (IPW), cultivation with polluted soil (CPS), and application of cyanobacterial manure (ACM). Three common leaf-vegetables in southern China were used in the pot experiments, including Ipomoea batatas L., Brassica juncea L., and Brassica alboglabra L. All leaf vegetables could bioaccumulate MC-LR under the three treatments, with much higher MC-LR bioaccumulation, especially root bioconcentration observed in ACM treatment than IPW and CPS treatments. An opposite trend in MC-LR degradation in soils of these treatments indicated that ACM could limit MC-LR degradation in soils and thus promote its bioaccumulation in the vegetables. MC-LR bioaccumulation could cause toxicity to the vegetables, with the highest toxic effects observed in ACM treatment. Similarly, bioaccumulation of MC-LR in the edible parts of the leaf-vegetables posed 1.1~4.8 fold higher human health risks in ACM treatment than in IPW and CPS treatments. The findings of this study highlighted a great concern on applications of cyanobacterial manure.

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Application of aptamer‐conjugated graphene oxide for specific enrichment of microcystin‐LR in Achatina fulica prior to matrix‐assisted laser desorption ionization mass spectrometry

Feng,

Dong,

Wang

et al. 2023

Electrophoresis

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Microcystin‐LR (MC‐LR), as a hepatotoxin, can cause liver swelling, hepatitis, and even liver cancer. In this study, MC‐LR aptamer (Apt‐3) modified graphene oxide (GO) was designed to enrich MC‐LR in white jade snail (Achatina fulica) and pond water, followed by matrix‐assisted laser desorption ionization mass spectrometry (MALDI‐MS) analysis. Results indicated that the Apt‐3/PEG/GO nanocomposites were highly specific to MC‐LR, and the detection limit of MALDI‐MS was 0.50 ng/mL. Moreover, the MC‐LR can be released from nanocomposites at 75°C, thus, the reuse of Apt‐3/PEG/GO is realized. Real sample analysis indicated that the Apt‐3/PEG/GO nanocomposites coupled with MALDI‐MS were efficient in detecting trace amounts of MC‐LR in real samples. With the merits of being low cost, reusable, and easy to besynthesized, this Apt‐3/PEG/GO MALDI‐MS is expected to be comprehensively applied by anchoring suitable aptamers for different targets.

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High ecological and human health risks from microcystins in vegetable fields in southern China

Cited by 80 publications

References 46 publications

A Mini Review on Microcystins and Bacterial Degradation

A Mini Review on Microcystins and Bacterial Degradation

Bioaccumulation and Phytotoxicity and Human Health Risk from Microcystin-LR under Various Treatments: A Pot Study

Application of aptamer‐conjugated graphene oxide for specific enrichment of microcystin‐LR in Achatina fulica prior to matrix‐assisted laser desorption ionization mass spectrometry

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