Hepatitis a in Lebanon: A Changing Epidemiological Pattern

Sacy, Robert; Haddad, M.; Baasiri, Ghassan; Khoriati, Adlette; Gerbaka, Bernard; Abu‐Elyazeed, Remon

doi:10.4269/ajtmh.2005.73.453

Cited by 47 publications

(28 citation statements)

References 20 publications

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“…This epidemiological profile of hepatitis A is in accordance with the tendency seen in seroprevalence studies carried out in some Brazilian population groups (Vitral et al 1998a, b, Clemens et al 2000, Tanaka 2000. This profile has also been observed in other countries where standards of living are higher (Chen 2003, Kang et al 2004, Tosun et al 2004, Letaief et al 2005, Sacy et al 2005. It could be suggested that the observed drop in the hepatitis A mortality rate results from increases in the quality of health care and greater availability of liver transplantation in specialized centers in major urban cities of the country within the last decade.…”

Section: Hepatitis a In Brazilsupporting

confidence: 87%

“…Several countries, such as those in Southeast Asia, have presented socioeconomic improvements in recent decades. In those countries, a significant decline in HAV seroprevalence has been seen among the youngest individuals (Chen 2003, Kang et al 2004, Tosun et al 2004, Letaief et al 2005, Manfredi et al 2005, Sacy et al 2005.…”

Section: The Impact Of Socioeconomic Improvements On the Prevalence Omentioning

confidence: 99%

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Epidemiological pattern and mortality rates for hepatitis A in Brazil, 1980-2002: a review

Vitral¹,

Gaspar

Souto

2006

Mem. Inst. Oswaldo Cruz

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Section: Hepatitis a In Brazilsupporting

confidence: 87%

Section: The Impact Of Socioeconomic Improvements On the Prevalence Omentioning

confidence: 99%

Epidemiological pattern and mortality rates for hepatitis A in Brazil, 1980-2002: a review

Vitral¹,

Gaspar

Souto

2006

Mem. Inst. Oswaldo Cruz

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“…A decrease in the prevalence of HAV infection was observed by Afegbua et al 48 in schoolchildren and adolescents in Kaduna, Nigeria, which was attributed to improvements in sanitation, water supply and living standards that were locally implemented in the last three decades. The HAV seroprevalence rate in Lebanon also decreased by 40% in children aged 1-5 and by 85% in children aged 6-12 in 1982 to 10.5% and 27.7%, respectively, in 2005 49 .…”

Section: Municipality Of Campos Dos Goytacazesmentioning

confidence: 94%

Hepatitis A seroprevalence in public school children in Campos dos Goytacazes, Rio de Janeiro State, Brazil, prior to the introduction of the hepatitis A universal childhood vaccination

et al. 2016

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This cross-sectional study was carried out between August 2011 and July 2012 in the city of Campos dos Goytacazes in Rio de Janeiro State, Brazil. Dried blood spot samples were collected on filter paper from 919 individuals between the ages of 1 and 19 and were tested for antibodies against the hepatitis A virus (anti-HAV). The total prevalence was 20.7%, while 94.7% of children under the age of 5 were found to be susceptible to HAV infection. The prevalence of anti-HAV increased with age, reaching 33.3% among individuals aged between 15 and 19, thereby indicating that this municipality has a low level of endemicity for hepatitis A. Age, non-white skin color, accustomed to swimming in the river and more than five people living at home were the factors that were associated with an increase in the chance of a positive anti-HAV result. Mother's education level (secondary or tertiary) was considered a protective factor for HAV infection. The data obtained showed that a large proportion of the children from Campos dos Goytacazes were at risk of HAV infection, which should be minimized with the introduction of the vaccination program against hepatitis A that was launched in the municipality in 2011.

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“…Nos últimos anos, as melhorias nas condições socioeconômicas e sanitárias que ocorreram em alguns países em desenvolvimento propiciaram alterações na epidemiologia de algumas doenças, entre elas, a hepatite A [5][6][7][8][9] .…”

Section: Introductionunclassified

Seroprevalence of hepatitis A in children and adolescents

et al. 2011

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Objectives: To determine the seroprevalence of hepatitis A (HAV) in children and adolescents aged 1 to 14 years, and to identify factors associated with a history of infection.Methods: This was a cross-sectional epidemiological study, conducted form February to August 2006 in the city of Curitiba, Paraná, Brazil, and the surrounding municipalities (Greater Curitiba). Laboratory analysis comprised qualitative assay for total HAV antibodies in whole blood samples.Results: A total of 901 children and adolescents were recruited for the study. Age distribution was as follows: 1 to 4 years, n = 237 (26.3%); 5 to 9 years, n = 313 (34.7%); and 10 to 14 years, n = 351 (39%). The global rate of seroprevalence was 19.8%, and seroprevalence rates by age group were 3%, 21.1% and 29.9% respectively (p < 0.01). Multivariate analysis demonstrated that the following factors, in combination, had a positive association with the prevalence rate of antibodies against HAV in the study population: age groups 5 to 9 and 10 to 14 years, living in a household with more than one inhabitant per room, shared eating area and low per capita income. Conclusions:The results show a low prevalence of antibodies against HAV, which justifies the use of prophylactic measures, including early vaccination. J Pediatr (Rio J). 2011;87(5):419-24:Hepatitis A, seroepidemiological study, child, adolescent. ResumoObjetivos: Avaliar a soroprevalência de hepatite A (VHA) em crianças e adolescentes com idade entre 1 e 14 anos, e identificar fatores associados à infecção prévia.Métodos: Estudo epidemiológico transversal, realizado entre fevereiro e agosto de 2006, em Curitiba, Paraná, Brasil, e em sua região metropolitana. A análise laboratorial constituiu-se de pesquisa qualitativa de anticorpos totais para o VHA em amostra de sangue total. Resultados: No estudo, 901 crianças e adolescentes foram incluídos.A distribuição por faixa etária foi: 237 (26,3%) entre 1 e 4 anos; 313 (34,7%) entre 5 e 9 anos; e 351 (39%) entre 10 e 14 anos. A taxa de soroprevalência geral encontrada foi de 19,8%, e por grupo etário foi de 3, 21,1 e 29,9% (p < 0,01), respectivamente. Na análise multivariada, demonstrou-se que os fatores que, em conjunto, mantiveram associação positiva com as prevalências de anticorpos contra o VHA na população estudada foram: faixa etária de 5 a 9 e 10 a 14 anos, morar em casas com um ou mais habitantes por cômodo, frequentar refeitório comunitário e ter baixa renda per capita. Conclusões:Os resultados demonstraram uma baixa prevalência de anticorpos contra o VHA, o que justifica o uso de medidas profiláticas, que incluem a vacinação precoce. J Pediatr (Rio J). 2011;87(5):419-24:Hepatite A, estudo soroepidemiológico, criança, adolescente. Seroprevalence of hepatitis A in children and adolescents IntroduçãoO vírus da hepatite A (VHA) é o maior responsável por quadros de hepatite aguda viral em crianças 1 e também é responsável por 75% de todos os casos de hepatite viral no mundo. Essa doença apresenta distribuição mundial, ocorrendo com maior fr...

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Hepatitis a in Lebanon: A Changing Epidemiological Pattern

Cited by 47 publications

References 20 publications

Epidemiological pattern and mortality rates for hepatitis A in Brazil, 1980-2002: a review

Epidemiological pattern and mortality rates for hepatitis A in Brazil, 1980-2002: a review

Hepatitis A seroprevalence in public school children in Campos dos Goytacazes, Rio de Janeiro State, Brazil, prior to the introduction of the hepatitis A universal childhood vaccination

Seroprevalence of hepatitis A in children and adolescents

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