Health Status of UK Patients with Active Tuberculosis Starting Therapy.

Kruijshaar, ME; Lipman, Marc; Essink-Bot, M. L.; Lozewicz, S.; Creer, Dean; Dart, S; Sadler, H.; Maguire, Helen; Abubakar, Ibrahim

doi:10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1416

Cited by 40 publications

(106 citation statements)

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“…17 Likewise, a study from the United Kingdom (UK) reported compromised HRQoL across SF-36 health domain scales and component summary measures. 29 However, contrary to the findings of our study, study from Northern Region of Malaysia by Atif M 16 showed that, at the start of the treatment, mental health was more affected than the physical health. With regard to HRQoL scores at the end of the intensive phase (8 th week), the findings of this study showed gradual improvement for all health domain scales and summary measures.…”

Section: 27contrasting

confidence: 96%

“…A similar trend in the improvement of HRQoL scores in association with TB treatment was reported elsewhere. 25,29 The study demonstrated the HRQoL of TB patient has been improving with the treatment, where the physical health tended to recover more quickly than the mental well-being. RE was the most affected domain and was improved drastically compared to other domains.…”

Section: 27mentioning

confidence: 97%

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A Study on Assessment of Patients Health Related Quality of Life During Tuberculosis Treatment in a Tertiary Care Teaching Hospital

Patil¹,

Rawal²,

Anuraj³

et al. 2016

IJOPP

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Background: Tuberculosis is one of the leading causes of mortality and morbidity around the world, infecting approximately 8 billion people, with an annual death rate of close to 1 million. The present study was conducted to evaluate the impact of tuberculosis treatment on health related quality of life (HRQoL) of patients with active and inactive tuberculosis by evolving HRQoL questionnaire (SF-36v2). Methodology: A prospective follow-up study was conducted for total 70 patients (56 men and 14 women) diagnosed with tuberculosis (TB) in Navodaya Medical College Hospital & Research Centre, Raichur for a period of 6 months. The HRQoL of TB patients was assessed in three phases: at the onset of treatment, at one month (middle of intensive phase) and two months (end of intensive phase), after the initiation of anti-tuberculosis therapy. Results: A total of 70 patients completed the SF-36v2 questionnaire at the start of their treatment. Out of these, 53 and 41 completed the questionnaire at the second and third follow-ups, respectively. The mean physical component summary (PCS) scores at the start of the treatment, after one month and at the intensive phase were 42.09 ± 16.77, 53.89 ± 13.64 and 65.24 ± 12.86, respectively. Similarly, the mean mental component summary (MCS) scores at the start of the treatment, after one month and at the intensive phase were 43 ± 17.07, 52.19 ± 14.12 and 62.17 ± 15.12, respectively. Conclusion: The HRQoL improved with the treatment, the scores on component summary measures revealed the improvement of both physical and mental health among study patients at the end of intensive phase.

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Section: 27contrasting

confidence: 96%

Section: 27mentioning

confidence: 97%

A Study on Assessment of Patients Health Related Quality of Life During Tuberculosis Treatment in a Tertiary Care Teaching Hospital

Patil¹,

Rawal²,

Anuraj³

et al. 2016

IJOPP

View full text Add to dashboard Cite

show abstract

“…All these articles were published in English. The data was based on comparative studies of TB population from China , two from Malaysia [18,23], five from India [14,15,29,[35][36][37][38], four from Canada [5,24,25,30] one form each UK [17] Pakistan [35], Spain [36] Taiwan [28] South Africa [37] and Turkey [39]. Among the selected articles fourteen studies were cross sectional [5,14,26,27,30,33,[34][35][36][37][38][39][40] and sixteen were prospective cohort based studies [15][16][17][18][19][20][21][22][23][24][25][26]29,31,32,41].…”

Section: Summary Of Resultsmentioning

confidence: 99%

“…Generic instrument measures were used in 10 studies with different language versions of SF-36 [5,[16][17][18][19][20]24,25,38,40,41]. SF-36 is a generic health outcomes measure consisting of 36 items aggregated into eight sub-scales of PF (physical functioning), RP (role physical), BP (body pain), GH (general health), VT (vitality), SF (social functioning), RE (role emotion) and MH (mental health) [43].…”

Section: Measurement Properties Of Hrqol Instrumentsmentioning

confidence: 99%

“…Studies have reported that when patients were evaluated with SF-36, they showed significant improvements in HRQoL at the completion of intensive phase of treatment [17,20]. A validation study of SF36 was described by Chamla [16] which suggested that the validity and reliability scores were high at the end of the treatment with Cronchbachs score >0.7 [16].…”

Section: Measurement Properties Of Hrqol Instrumentsmentioning

confidence: 99%

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Health Status and Quality of Life in Tuberculosis: Systematic Review of Study Design, Instruments, Measuring Properties and Outcomes

Khan¹,

Tangiisuran²,

Imtiaz³

et al. 2017

Health Sci J

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A systematic review and meta-analysis of the impact of tuberculosis on health-related quality of life

2012

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PurposeTo summarize the impact of tuberculosis (TB) on quantitative measures on self-reported health-related quality of life (HRQOL).MethodsWe searched eight databases to retrieve all peer-reviewed publications reporting original HRQOL data for persons with TB. All retrieved abstracts were considered for full-text review if HRQOL was quantitatively assessed among subjects with TB. Full-text articles were reviewed by two independent reviewers using a standardized abstraction form to collect data on socio-demographic characteristics, questionnaire administration, and mean HRQOL scores. Meta-analyses were performed for standardized mean differences in HRQOL scores, comparing subjects treated for active TB with subjects treated for latent TB infection (LTBI), or with healthy controls, at similar time points with respect to diagnosis and/or treatment.ResultsFrom over 15,000 abstracts retrieved, 76 full-text articles were reviewed, which represented 28 unique cohorts (6,028 subjects) reporting HRQOL among subjects with active TB; 42 % were women and mean age was 42 years. Data on key social and behavioral determinants were limited. Within individual studies and in meta-analyses, subjects with active TB disease consistently reported worse HRQOL than concurrently evaluated subjects treated for LTBI. However, meaningful improvements in HRQOL throughout active TB treatment were reported by longitudinal studies.ConclusionsIn a variety of studies, in different settings and using different instruments, subjects with active TB consistently reported poorer HRQOL than persons treated for LTBI. Future research on HRQOL and TB should better address social and behavioral health determinants which may also affect HRQOL.

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Health Status of UK Patients with Active Tuberculosis Starting Therapy.

Cited by 40 publications

References 0 publications

A Study on Assessment of Patients Health Related Quality of Life During Tuberculosis Treatment in a Tertiary Care Teaching Hospital

A Study on Assessment of Patients Health Related Quality of Life During Tuberculosis Treatment in a Tertiary Care Teaching Hospital

Health Status and Quality of Life in Tuberculosis: Systematic Review of Study Design, Instruments, Measuring Properties and Outcomes

A systematic review and meta-analysis of the impact of tuberculosis on health-related quality of life

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