Background: Tuberculosis is one of the leading causes of mortality and morbidity around the world, infecting approximately 8 billion people, with an annual death rate of close to 1 million. The present study was conducted to evaluate the impact of tuberculosis treatment on health related quality of life (HRQoL) of patients with active and inactive tuberculosis by evolving HRQoL questionnaire (SF-36v2). Methodology: A prospective follow-up study was conducted for total 70 patients (56 men and 14 women) diagnosed with tuberculosis (TB) in Navodaya Medical College Hospital & Research Centre, Raichur for a period of 6 months. The HRQoL of TB patients was assessed in three phases: at the onset of treatment, at one month (middle of intensive phase) and two months (end of intensive phase), after the initiation of anti-tuberculosis therapy. Results: A total of 70 patients completed the SF-36v2 questionnaire at the start of their treatment. Out of these, 53 and 41 completed the questionnaire at the second and third follow-ups, respectively. The mean physical component summary (PCS) scores at the start of the treatment, after one month and at the intensive phase were 42.09 ± 16.77, 53.89 ± 13.64 and 65.24 ± 12.86, respectively. Similarly, the mean mental component summary (MCS) scores at the start of the treatment, after one month and at the intensive phase were 43 ± 17.07, 52.19 ± 14.12 and 62.17 ± 15.12, respectively. Conclusion: The HRQoL improved with the treatment, the scores on component summary measures revealed the improvement of both physical and mental health among study patients at the end of intensive phase.
Cutis verticis gyrata (CVG) is a rare scalp condition characterized by scalp skin redundancy that manifests as thickening of scalp skin with furrows and convoluted folds, giving out a cerebriform pattern of external appearance. CVG might manifest either as primary or secondary to an underlying cause. This case demonstrates the typical imaging findings of CVG that was provisionally diagnosed on imaging and confirmed on histopathology as secondary to cerebriform intradermal nevus in a healthy adolescent girl presenting with history of focal irregular scalp thickening since birth.
We reported a case of two days old baby with typical features of Acrocallosal syndrome. The characteristic features of this syndrome are craniofacial abnormalities, distinctive digital malformation and corpus callosum hypoplasia/agenesis. USG cranium and NECT of brain reveals characteristic features of corpus callosum agenesis and posterior fossa arachnoid cyst.
A rare case of 5yrs old boy came with chief complaint of swelling at nasal bridge since birth. It was gradually increasing in size, with recurrent attacks of cold. No history of trauma or fever. Radiograph of PNS shows opacification of left nasal cavity with deviated nasal septum towards right. Patient was further evaluated with CT-PNS and MRI-Brain (3-d drive thin sections).Finally diagnosis of naso-ethmoid encephalocele was made. Patient underwent surgery and final histopathological diagnosis was nasoethmoidal encephalocele.
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