Green synthesis of novel quinoxaline sulfonamides with antibacterial activity

Recent advances in the transition-metal-free synthesis of quinoxalines

“…Massah et al , in 2017, disclosed a catalyst-free protocol for the synthesis of quinoxaline derivatives 38 from the reaction of o -phenylenediamine 35 and phenacyl bromide 33 under reflux condition using ethanol as the green solvent ( Scheme 11 ). 78 The products were obtained in 70–85% yields. The synthesized quinoxaline derivatives were extended to quinoxaline sulfonamides 39 via a two-step reaction.…”

Synthesis of novel antibacterial and antifungal quinoxaline derivatives

“…Quinoxaline derivatives, a class of N-containing heterocyclic compounds, which is an important chemical intermediate, have played an important role in the design and synthesis of new heterocyclic compounds, 13 and are of great signicance for drug discovery. 14 Quinoxaline derivatives exhibit broadspectrum bioactivities, such as antibacterial, 15,16 antiviral, 17,18 antitumor, [19][20][21] anti-tuberculous, 22 anticancer, 23,24 and so on. 25,26 Therefore, quinoxaline moieties widely exist in pesticides and medicines, and some commercialized pesticides used in agricultural production, including quintiofos, quizalofop-p-ethyl, chloramphenicol, olaquindox, and so forth (Fig.…”

Study on Adsorption Properties of Ammonium Exchanged Chabazite for CO2

“…Zeolite can be divided into A type, X type, Y type and so on, according to the different arrangement of the internal silicon aluminum in the current report. [11][12][13][14][15][16] Chabazite is a microporous zeolite with a pore size of less than 4 angstrom (as shown in Figure 1). It is a common sense that the currently known pure chabazite only has the low ratio of Si/Al rather than more forms.…”