Graphene-encapsulated silica as matrix solid-phase dispersion extraction sorbents for the analysis of poly-methoxylated flavonoids in the leaves of Murraya panaculata (L.) Jack

Abstract

In this study, graphene-encapsulated silica was synthesized by a hydrothermal reduction strategy. The presence of silica in graphene was identified by Fourier-transform infrared spectrometry, X-ray diffraction and scanning electron microscopy. The graphene-encapsulated silica subsequently was used as adsorbent for matrix solid-phase dispersion extraction of poly-methoxylated flavonoids from the dried leaves of Murraya panaculata (L.) Jack. Compared with the other adsorbents (graphene, silica gel, C18 silica, neutral alumina, diatomaceous earth) and without any adsorbents, better results were obtained. Then a method for analysis of poly-methoxylated flavonoids was established by coupling matrix solid-phase dispersion extraction with ultra high performance liquid chromatography and UV detection. Compared with reflux extraction and ultrasonic extraction, the proposed method is quicker, more efficient and more environmental protection. Less than 10 min is needed from extraction to detection.

Extraction approaches used for the determination of biologically active compounds (cyclitols, polyphenols and saponins) isolated from plant material

“…Graphene‐encapsulated silica was successfully applied for extraction of poly‐methoxylated flavonoids isolated from Murraya paniculata L . leaves and they presented a recovery degree of more than 92% .…”

Simultaneous determination and qualitative analysis of six types of components in Naoxintong capsule by miniaturized matrix solid‐phase dispersion extraction coupled with ultra high‐performance liquid chromatography with photodiode array detection and quadrupole time‐of‐flight mass spectrometry

“…At present, MSPD has attracted increasing interests and has been applied in various industries, such as pesticide residues in fruits and vegetables, preservatives in cosmetics and household products, illegal dyes in food, heavy metal in water, chemicals in human placental tissue, and hazardous chemicals in animal tissue [12][13][14][15][16][17][18][19][20]. More and more applications have been reported in the determination of natural products, especially in herbs [19,[21][22][23][24][25][26][27][28][29]. Compared with conventional extraction methods, MSPD has proven to be a simple, flexible, and versatile strategy with a small aliquot and less time consum-ing [11].…”

“…Peaks 2,12,13,15,17,19,26,27,29,34,40,56, 70, and 85 with no ester bond produced characteristic fragment ions by the loss of components such as CO 2 (44 Da), CO (28 Da), and H 2 O (18 Da) owing to the moieties of carboxyl, carbonyl, or hydroxyl they contain.Peaks 12,13,15,17,19,27,29,34,40, and 55 were unambiguously identified by comparing chromatographic and mass spectral information with the reference standards.Peaks 2,26,56,62, 70, 82, and 85 were tentatively identified by Stability, intraday, and interday of the analysis compounds…”

Graphene nanoplatelets based matrix solid-phase dispersion microextraction for phenolic acids by ultrahigh performance liquid chromatography with electrochemical detection

“…The choice of a suitable sorbent material is a significant factor in MSPDM process. Commonly used adsorbents are silica gel, C 18 and florisil, but they show low selectivity for analytes and low efficiency in the extraction of the low content compounds 28 . Hence, it is important to seek the more selective and efficient adsorbents.…”