Extraction approaches used for the determination of biologically active compounds (cyclitols, polyphenols and saponins) isolated from plant material

Ligor, Magdalena; Rațiu, Ileana-Andreea; Kiełbasa, Anna; Al-Suod, Hossam; Buszewski, Bogusław

doi:10.1002/elps.201700431

Cited by 43 publications

(25 citation statements)

References 139 publications

(141 reference statements)

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“…Some of the chromatographic techniques generally used for the composition analysis of honey samples, can also be employed for the analysis of sugars and cyclitols, the most widely used being high performance liquid chromatography (HPLC) [11,12]. Gas chromatography with mass spectrometry (GC-MS) is quite often used as well, but this technique involves a derivatization step [13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Correlation Study of Honey Regarding their Physicochemical Properties and Sugars and Cyclitols Content

et al. 2019

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Honey is a natural sweetener, with an osmotic effect on microorganisms due to the increased sugar content and low amount of water. Cyclitols are minor constituents of honey. They play a defensive role in plants against unfavorable environmental conditions. Honey's physicochemical properties can vary, resulting in a wide range of colors, flavors, scents, antioxidant activity, dissimilar values of pH, acidity, electrical conductivity, etc. Some literature regarding correlation between honey types is already available, but a comprehensive study displaying an ample evaluation of multifarious aspects is still needed. This study focuses on the correlation between 18 honey types, originating from 10 countries, collected during four years, summarizing a total of 38 samples. A total of 6 physicochemical properties and 18 target components (sugars and cyclitols) were considered as variables. A correlation analysis is presented between the investigated parameters and between honey types, together with the statistical analysis which allowed for observation of the clusters' distribution according with the investigated variables.

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Section: Introductionmentioning

confidence: 99%

Correlation Study of Honey Regarding their Physicochemical Properties and Sugars and Cyclitols Content

et al. 2019

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“…Furthermore, the extraction is a fully controlled process, which eliminates the problem of batch to batch variability caused by changing extraction conditions. Thus, ASE is a fast, efficient, and more environmentally friendly approach and has been proven to be a reliable and reproducible extraction technique for numerous types of natural matrices (Borges et al, 2019; Ligor, Ratiu, Kielbasa, Al‐Suod, & Buszewski, 2018; Widelski et al, 2018).…”

Section: Methodsmentioning

confidence: 99%

Exhaustive extraction of cyclopeptides from Amanita phalloides: Guidelines for working with complex mixtures of secondary metabolites

Chialvo

Griffin

Reed

et al. 2020

Ecology and Evolution

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Understanding plant‐insect interactions is an active area of research in both ecology and evolution. Much attention has been focused on the impact of secondary metabolites in the host plant or fungi on these interactions. Plants and fungi contain a variety of biologically active compounds, and the secondary metabolite profile can vary significantly between individual samples. However, many experiments characterize the biological effects of only a single secondary metabolite or a subset of these compounds. Here, we develop an exhaustive extraction protocol using an accelerated solvent extraction protocol to recover the complete suite of cyclopeptides and other secondary metabolites found in Amanita phalloides (death cap mushrooms) and compare its efficacy to the “Classic” extraction method used in earlier works. We demonstrate that our extraction protocol recovers the full suite of cyclopeptides and other secondary metabolites in A. phalloides unlike the “Classic” method that favors polar cyclopeptides. Based on these findings, we provide recommendations for how to optimize protocols to ensure exhaustive extracts and also the best practices when using natural extracts in ecological experiments.

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“…They are used as important ingredients in medicines, seasonings, beverages, cosmetics, dyes, etc. due to their content of various bioactive compounds [1,2]. One of the major groups of plant secondary metabolites, which fulfill a plethora of biological functions, is the cyclitols (cycloalkane polyols or sugar alcohols).…”

Section: Introductionmentioning

confidence: 99%

Supercritical fluid extraction in isolation of cyclitols and sugars from chamomile flowers

Al-Suod

Rațiu

Krakowska-Sieprawska

et al. 2019

J of Separation Science

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The aim of the present study was to develop an optimization procedure for supercritical fluid extraction parameters, in order to obtain the highest possible yield of sugars and cyclitols from plant material. Response surface methodology based on Box-Behnken design was applied to evaluate the effect of: temperature (40, 60, 80 • C), pressure (100, 200, 300 bar), and co-solvent (methanol) percentage (20, 25, 30%). As a result of the optimization process, we found that the highest amount of sugars (15.02 mg/gof dried material) and cyclitols (0.86 mg/g of dried material) was obtained when the following parameters were applied: 80 • C, 228 bar, and 30% of methanol.Moreover, co-solvent concentration and temperature had a higher influence onto the obtained amounts compared with the pressure. K E Y W O R D S chamomile, cyclitols isolation, response surface methodology, sugars isolation, supercritical fluid extraction Article Related Abbreviations: ANOVA, analysis of variance; IS, internal standard; RSM, response surface methodology; SFE, supercritical fluid extraction; UAE, ultrasound-assisted extraction.Several studies reported cyclitols as anti-oxidant, antiinflammatory, and anticancer agents [3][4][5]. Other studies demonstrated that some cyclitols such as D-pinitol and chiroinositol possess insulin-like properties and they can be useful in treating of diabetes by reducing the level of blood glucose [6,7].Chamomile is a traditional herb used for medicinal purposes [8]. It is a member of Asteraceae family, represented by two common varieties viz. German Chamomile (Matricaria recutita L.) and Roman Chamomile (Chamaemelum nobile). The dried flowers are used for preparing the chamomile tea known for its multiple effects like: calming effect of fever, reassuring of nerves and reducer of anxiety of the nightmares, insomnia, and other sleep problems [9]. Moreover, the essential oils of chamomile are used in the pharmaceutical, cosmetic, perfumery, and aromatherapy industries [10,11].The interest in obtaining bioactive compounds from plants for their further uses and applications have motivated the researchers to develop new and efficient methodologies

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Extraction approaches used for the determination of biologically active compounds (cyclitols, polyphenols and saponins) isolated from plant material

Cited by 43 publications

References 139 publications

Correlation Study of Honey Regarding their Physicochemical Properties and Sugars and Cyclitols Content

Correlation Study of Honey Regarding their Physicochemical Properties and Sugars and Cyclitols Content

Exhaustive extraction of cyclopeptides from Amanita phalloides: Guidelines for working with complex mixtures of secondary metabolites

Supercritical fluid extraction in isolation of cyclitols and sugars from chamomile flowers

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