Gold nanoparticle based biosensors for rapid pathogen detection: A review

Hegde, Madhu; Pai, Padmini; Shetty, Manasa Gangadhar; Shakuntala, K.

doi:10.1016/j.enmm.2022.100756

Cited by 23 publications

(16 citation statements)

References 79 publications

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“…Biosensors are devices that are created by combining a sensitive transducer element with a selective biorecognition element [ 80 ]. Stimulus-responsive DNA hydrogel can be a reliable material for the biological characteristic elements in biosensors due to their specificity and rapid response to stimuli.…”

Section: Stimulus-responsive Dna Hydrogel-based Biosensormentioning

confidence: 99%

Stimulus-Responsive DNA Hydrogel Biosensors for Food Safety Detection

Wang

Lai

et al. 2023

Biosensors

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Food safety has always been a major global challenge to human health and the effective detection of harmful substances in food can reduce the risk to human health. However, the food industry has been plagued by a lack of effective and sensitive safety monitoring methods due to the tension between the cost and effectiveness of monitoring. DNA-based hydrogels combine the advantages of biocompatibility, programmability, the molecular recognition of DNA molecules, and the hydrophilicity of hydrogels, making them a hotspot in the research field of new nanomaterials. The stimulus response property greatly broadens the function and application range of DNA hydrogel. In recent years, DNA hydrogels based on stimulus-responsive mechanisms have been widely applied in the field of biosensing for the detection of a variety of target substances, including various food contaminants. In this review, we describe the recent advances in the preparation of stimuli-responsive DNA hydrogels, highlighting the progress of its application in food safety detection. Finally, we also discuss the challenges and future application of stimulus-responsive DNA hydrogels.

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Section: Stimulus-responsive Dna Hydrogel-based Biosensormentioning

confidence: 99%

Stimulus-Responsive DNA Hydrogel Biosensors for Food Safety Detection

Wang

Lai

et al. 2023

Biosensors

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“…Owing to their good conductivity, AuNPs can signicantly reduce the distance between electron donors and acceptors, and accelerate the transfer of electrons to the electrode surface, thereby enhancing selectivity and sensitivity of the corresponding sensors. [94][95][96] The presence of MOF can control the size of AuNPs and prevent agglomeration of the composite. Hence, MOF/AuNPs composites can be used in a wide range of applications for improving the performance of modied electrodes.…”

Section: Mof/au Nanoparticles (Aunps) Compositementioning

confidence: 99%

Progress and opportunities for metal–organic framework composites in electrochemical sensors

Zhang

Ding

et al. 2023

RSC Adv.

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“…Advents in plasmonics have led to the emergence of SERS with impressive signal enhancements over traditional Raman spectroscopy [ 16 ]. SERS-based sensing is being widely used for the trace detection of different molecules, such as explosives [ 17 ], pesticides [ 18 , 19 ], food adulterants [ 20 , 21 ], drugs [ 22 ], biomolecules [ 23 , 24 , 25 , 26 , 27 ], medicine [ 28 , 29 , 30 ], and microorganisms [ 31 ].…”

Section: Introductionmentioning

confidence: 99%

Recent Trends in SERS-Based Plasmonic Sensors for Disease Diagnostics, Biomolecules Detection, and Machine Learning Techniques

2023

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Surface-enhanced Raman spectroscopy/scattering (SERS) has evolved into a popular tool for applications in biology and medicine owing to its ease-of-use, non-destructive, and label-free approach. Advances in plasmonics and instrumentation have enabled the realization of SERS’s full potential for the trace detection of biomolecules, disease diagnostics, and monitoring. We provide a brief review on the recent developments in the SERS technique for biosensing applications, with a particular focus on machine learning techniques used for the same. Initially, the article discusses the need for plasmonic sensors in biology and the advantage of SERS over existing techniques. In the later sections, the applications are organized as SERS-based biosensing for disease diagnosis focusing on cancer identification and respiratory diseases, including the recent SARS-CoV-2 detection. We then discuss progress in sensing microorganisms, such as bacteria, with a particular focus on plasmonic sensors for detecting biohazardous materials in view of homeland security. At the end of the article, we focus on machine learning techniques for the (a) identification, (b) classification, and (c) quantification in SERS for biology applications. The review covers the work from 2010 onwards, and the language is simplified to suit the needs of the interdisciplinary audience.

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Gold nanoparticle based biosensors for rapid pathogen detection: A review

Cited by 23 publications

References 79 publications

Stimulus-Responsive DNA Hydrogel Biosensors for Food Safety Detection

Stimulus-Responsive DNA Hydrogel Biosensors for Food Safety Detection

Progress and opportunities for metal–organic framework composites in electrochemical sensors

Recent Trends in SERS-Based Plasmonic Sensors for Disease Diagnostics, Biomolecules Detection, and Machine Learning Techniques

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