Goblet cell mucin distribution in the small intestine of newborn goat kids fed lyophilized bovine colostrum

Machado‐Neto, Raul; Pontin, Mariana Caroline; Nordi, Wiolene Montanari; Lima, Anali Linhares; Moretti, Débora Botéquio

doi:10.1016/j.livsci.2013.06.033

Cited by 20 publications

(12 citation statements)

References 21 publications

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“…Similarly, an increase in numbers of mucus secreting goblet cells is present in the colon of the human (Forstner, 1978) and three insectivorous mammalian species (Boonzaier et al, 2013). Due to the vulnerability of sialomucins to bacterial degradation, sulfomucin secreting cells are expected to dominate in the large intestine where the bacterial load is high (Fontaine et al, 1996, Deplancke and Gaskins, 2001, Hino et al, 2012and Machado-Neto et al, 2013. This was true in M. rex in the present study where the number of sulfomucin secreting goblet cells increased significantly towards the distal GIT.…”

Section: Discussionsupporting

confidence: 63%

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The distribution of mucous secreting cells in the gastrointestinal tracts of three small rodents from Saudi Arabia: Acomys dimidiatus , Meriones rex and Meriones libycus

et al. 2016

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Section: Discussionsupporting

confidence: 63%

“…The large intestine contains the greatest number of mucin secreting goblet cells and its secretion protects the intestinal epithelium against harm done by intestinal microorganisms (Machado-Neto et al, 2013). Atuma et al (2001) found that the human colonic mucosa contained a significantly thicker mucus layer compared to the rest of the GIT.…”

Section: Discussionmentioning

confidence: 99%

The distribution of mucous secreting cells in the gastrointestinal tracts of three small rodents from Saudi Arabia: Acomys dimidiatus , Meriones rex and Meriones libycus

et al. 2016

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“…Sulphomucins play a prominent role in the increase of the mucus viscosity in the distal region (Croix et al, ) and may aid in the expulsion of indigestible, hard chitin if ingested by insect eaters (Freeman, ; Okon, ). Furthermore, as sulphomucins are less prone to degradation by bacterial glycosidases and host proteases (Machado‐Neto, Pontin, Nordi, Lima, & Moretti, ), they are best suited to safeguard against bacterial translocations and are a source of sulphate for the sulphate‐reducing bacteria commonly found in the colon (Croix et al, ).…”

Section: Discussionmentioning

confidence: 99%

A comparative morphological and histological study of the gastrointestinal tract of four insectivorous bat species: Asellia tridens, Chaerephon pumilus, Nycteris thebaica, Rhinopoma hardwickii

Aylward

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Alagaili

et al. 2019

Journal of Morphology

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Various studies address the morphology of the gastrointestinal tracts (GITs) of insectivorous bat species. However, detailed morphometric studies including mucin histochemistry are scarce. This study compares various GIT measurements as well as the quantification of intestinal mucin secreting cells in four insectivorous bat species representing four different families of Chiroptera. Alcian blue/Periodic acid Schiff's stain was used to differentiate between acid and neutral mucin‐secreting cells while the Aldehyde fuchsin/Alcian blue stain further differentiated between two acid mucins, namely sialo‐, and sulphomucins. The number of cells was quantified and statistically analysed. All species had a simple GIT morphology represented by a simple, completely glandular stomach and the absence of a cecum. The exception was R. hardwickii, where a small cecum was observed which had histological mucosal features of both the small and large intestine. In R.hardwickii, distal to the cecum, typical colonic mucosal features such as the absence of villi and an abundance of goblet cells were observed. In all four species, the total number of goblet cells increased from the proximal to the distal intestinal regions. Mixed (acid and neutral) mucins dominated the entire GIT of all species. Neutral mucin‐secreting cells were observed in the gastric pylorus and proximal intestinal regions in all species. Brunner's glands stained positive for neutral mucins. Exclusively acid mucin‐secreting cells were seen in the distal intestinal regions of all species except N. thebaica. Sulphomucin‐secreting cells were the most prominent acid mucin cell‐type towards the distal intestine. The distribution of different mucin secreting cells indirectly provides information regarding the quality of the intestinal biofilm in the species studied.

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“…The same slides were then counterstained with 1% Ab pH = 2.5 and the total number of acidic goblet cells were counted. The number of goblet cells containing sialomucins was obtained by determining the difference between the total number of acidic mucin and number of sulphomucins (Kleessen, Hartman & Blaut ; Marchetti, Capacchietti, Sabbieti, Accili, Materazzi & Menghi ; Machado‐Neto, Pontin, Nordi, Lima & Moretti ).…”

Section: Methodsmentioning

confidence: 99%

Intestinal epithelium of juvenile douradoSalminus brasiliensis(Cuvier, 1816) fed diet with lyophilized bovine colostrum

et al. 2014

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The aim of this study was to evaluate the effect of lyophilized bovine colostrum (LBC) used as partial source of dietary protein on the histological characteristics of the intestinal epithelium of juvenile dourado Salminus brasiliensis. Juveniles were fed diets containing 0%, 10% or 20% of LBC inclusion for either 30 or 60 days. For the histological study, the intestine was divided into three segments, S1, S2 and posterior intestine. In the S1 segment, interaction between treatment and period was observed in the number of goblet cells containing sialomucin, effect of treatment in the total number of goblet cells and effect of period in the number of goblet cells containing sulphomucins (P < 0.05). In the S2 segment, effect of period was observed in the number of goblet cells containing acid, neutral and total mucins, sialomucins and the partial volume of the absorptive mucosa (Vv) (P < 0.05). In the posterior intestine, effect of period was observed in the thickness of muscle layer and number of goblet cells containing sialomucins and sulphomucins (P < 0.05). Considering the aspects studied, the presence of 0%, 10% or 20% of LBC in the diet did not significantly influence the enteric histological characteristics of juvenile dourado during the period of the study.

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Goblet cell mucin distribution in the small intestine of newborn goat kids fed lyophilized bovine colostrum

Cited by 20 publications

References 21 publications

The distribution of mucous secreting cells in the gastrointestinal tracts of three small rodents from Saudi Arabia: Acomys dimidiatus , Meriones rex and Meriones libycus

The distribution of mucous secreting cells in the gastrointestinal tracts of three small rodents from Saudi Arabia: Acomys dimidiatus , Meriones rex and Meriones libycus

A comparative morphological and histological study of the gastrointestinal tract of four insectivorous bat species: Asellia tridens, Chaerephon pumilus, Nycteris thebaica, Rhinopoma hardwickii

Intestinal epithelium of juvenile douradoSalminus brasiliensis(Cuvier, 1816) fed diet with lyophilized bovine colostrum

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