Glycosides from the Methanol Extract ofNotopterygium incisum

Abstract

Five new (1-5) and twelve known (6-17) different types of glycosides together with a known sesquiterpene triol (18) were isolated from the methanol extract of the rhizomes of Notopterygium incisum. The new structures were elucidated by means of spectroscopic and chemical methods to be pregn-5-en-3 β,20( S)-diol-3- O-bis-β-D-glucopyranosyl-(l → 2,1 → 6)-β-D-glucopyranoside (1), oleuropeic aldehyde 8-O-β-D-glucopyranoside (2), 2( R)-(3,4-dimethoxyphenyl)-propane-1,3-diol-1-O- β-D-glucopyranoside (3), eudesman-3 α,4 α,11-triol-11-O-β-D-glucopyranoside (4), and marmesin-11-O-β-D-glucopyranosyl-(1 → 6)-β-D-glucopyranoside (5). The absolute configuration of the aglycone in compound 3 was assigned by application of Klyne's rule.

Amelioration effect of natural bioactive flavonoids from Turbinaria ornata against oxidative stress induced neurochemical degradation and neurodegeneration

“…Ananthi et al [13] have elucidated the effective biological constituents from marine plants by polar solvent for the treatment of lipidized brain related diseases and disorders. The methanolic extracts were used to fractionate the active glycosidic constituents of T. ornata and evaluated for their biological activities [23].…”

Effect of Different Post-Harvest Processing Methods on the Chemical Constituents of Notopterygium franchetii by an UHPLC-QTOF-MS-MS Metabolomics Approach

“…Phytochemical studies have shown that coumarins, phenoloids, flavonoids and their glycosides, and essential oils are the main types of chemicals in NF [5,6,7]. Among these, coumarins, especially isoimperatorin, notopterol, and bergapten, are well known to be the major bioactive compounds, and contribute to NF’s anti-inflammatory, analgesic, and anti-cancer activities [8,9,10].…”

Identification of Nematicidal Constituents of Notopterygium incisum Rhizomes against Bursaphelenchus xylophilus and Meloidogyne incognita

“…Previous phytochemical investigations revealed that the rhizomes of N . incisum contained phenolic compounds, alkaloids, polyacetylenes, coumarins, sesquiterpenoids, and glycosides [21,22,23,24,25,26,27,28,29,30,31,32,33,34]. Pharmacological studies have revealed that its extracts or constituents possess anti-inflammatory, antioxidative, analgesic, and anti-influenza activity as well as antiproliferative activity against several cancer cell lines [21,22].…”