Glioma multifocal multicéntrico

T, Rodrigo Guerrero; L, Ingeborg López; R, Luis Cartier

doi:10.4067/s0717-92272010000400006

Cited by 2 publications

(3 citation statements)

References 9 publications

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“…Others compounds of type N 6 -substituted adenosines based on a regioselective 1-N-alkylation through Dimroth rearrangement were synthesized for the formation of biologically important of N 6 -benzyladenosine, N 6 -isopentenyl-adenosine, and their synthetic analogs [79, 83].…”

Section: Methods Of Synthesis Of Adenosine Derivatives Interaction Wmentioning

confidence: 99%

Adenosine: Synthetic Methods of Its Derivatives and Antitumor Activity

Valdés

Luna

Arévalo

et al. 2018

MRMC

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Since 1929, several researchers have conducted studies in relation to the nucleoside of adenosine (1) mainly distribution identifying, characterizing their biological importance and synthetic chemistry to which this type of molecule has been subjected to obtain multiple of its derivatives. The receptors that interact with adenosine and its derivatives, called purinergic receptors, are classified as A1, A2A, A2B and A3. In the presence of agonists and antagonists, these receptors are involved in various physiological processes and diseases. This review describes and compares some of the synthetic methods that have been developed over the last 30 years for obtaining some adenosine derivatives, classified according to substitution processes, complexation, mating and conjugation. Finally, we mention that although the concentrations of these nucleosides are low in normal tissues, they can increase rapidly in pathophysiological conditions such as hypoxia, ischemia, inflammation, trauma and cancer. In particular, the evaluation of adenosine derivatives as adjunctive therapy promises to have a significant impact on the treatment of certain cancers, although the transfer of these results to clinical practice requires a deeper understanding of how adenosine regulates the process of tumorigenesis.

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Section: Methods Of Synthesis Of Adenosine Derivatives Interaction Wmentioning

confidence: 99%

Adenosine: Synthetic Methods of Its Derivatives and Antitumor Activity

Valdés

Luna

Arévalo

et al. 2018

MRMC

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“…Sus síntomas son muy inespecíficos dados por cefalea, náuseas, emésis, vasodilatación cerebral y periférica, alteración del estado de conciencia, alteraciones retinianas (papiledema), hemiparesias y crisis convulsivas 41,49 , siendo los sitios más afectados son los lóbulos temporal, parietal y frontal 50 .…”

Section: Manifestaciones Clínicasunclassified

“…Puede presentar diseminación bihemisférica a través del cuerpo calloso, con afección de lóbulos frontales (Glioma en "alas de mariposa") 50,52 . Figura 2: TC con contraste.…”

Section: Diagnóstico Por Neuroimagenunclassified

Diagnóstico diferencial de lesiones cerebrales con realce en anillo en tomografía computarizada y resonancia magnética

Aljure

Arias

Monroy

et al. 2016

Duazary

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RESUMENLa tomografía computarizada y la resonancia magnética nuclear son técnicas imagenológicas de diagnóstico médico que ofrecen información excelente de diferentes procesos infecciosos, traumáticos o tumorales de cualquier parte del cuerpo humano. Con ellos se permitió la identificación de innumerables patologías y patrones característicos de las mismas, siendo una de ellas, el realce en anillo en el Sistema Nervioso Central. Numerosas patologías presentan este patrón imagenológico: Glioblastoma multiforme, síndromes desmielinizantes, metástasis, abscesos cerebrales, toxoplasmosis cerebral, neurocisticercosis, linfomas, entre otros. El objetivo del presente artículo es brindar una revisión general de las patologías más frecuentes en los servicios de imagenología, permitiendo su correlación con las características clínicas y brindando una ayuda al clínico que para establecer un diagnóstico adecuado. Palabras clave: Neuroimagen; Diagnóstico Diferencial; Encefalopatías ABSTRACTComputed tomography and magnetic resonance imaging are medical diagnostic imaging techniques that provide excellent information from different infectious, traumatic or tumor processes anywhere in the body. It is identifying with them many diseases and characteristic patterns of them, one of them the ring enhancement in the central nervous system allowed. Many diseases have this imaging pattern: Glioblastoma multiforme, demyelinating syndromes, metastases, brain abscesses, cerebral toxoplasmosis, neurocysticercosis, lymphomas, and others. The objective of this article is to provide an overview of the most common diseases in imaging services, allowing its correlation with clinical features and providing aid to the clinician to establish a proper diagnosis.

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Glioma multifocal multicéntrico

Cited by 2 publications

References 9 publications

Adenosine: Synthetic Methods of Its Derivatives and Antitumor Activity

Adenosine: Synthetic Methods of Its Derivatives and Antitumor Activity

Diagnóstico diferencial de lesiones cerebrales con realce en anillo en tomografía computarizada y resonancia magnética

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