Genetic Polymorphisms of α-lactalbumin and β-lactoglobulin in South Anatolian and East Anatolian Red Cattle

Yardibi, Hasret; Turkay, Gulhan; Mengi, Ahmet; Kaygısız, Ferhan; Öztabak, Kemal

doi:10.3923/ajava.2009.252.257

Cited by 6 publications

(5 citation statements)

References 25 publications

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“…Many scientists have established the influence of the GH gene on the growth and development of cattle. In addition, there is evidence of a relationship with the meat characteristics of livestock [12,[15][16].…”

Section: Introductionmentioning

confidence: 99%

Genetic profile and association of candidate gene polymorphism with productivity of Kalmyk cattle

Chimidova,

Ubushieva,

Ubushieva

et al. 2024

BIO Web Conf.

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The research was carried out in the laboratory of molecular genetic examination of the RNPC on reproduction of farm animals of the KalmSU named after B. B. Gorodovikov. The purpose of the research was to study the genetic profile and identify the influence of polymorphic candidate genes on the selection and breeding qualities of Kalmyk breed cattle. Analysis of these results by PCR-PDRF of Kalmyk bulls by the Tg locus revealed that 31% of 80 animal heads were carriers of the TT genotype associated with desirable traits, according to the GH locus in the breeding reproducer “Plodovitoye” revealed that 44% of 86 animals were carriers of the VV genotype associated with desirable economic characteristics and valuable qualities. This can be explained by the purposeful conduct of breeding work on breeding indicators in farms. Carriers of the VV genotype exceed their peers in the TT genotype by 9.1 kg (P>0.95). Based on the results obtained, it can be assumed that GH polymorphism has a positive effect on the meat productivity of Kalmyk bulls in comparison with TG.

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Section: Introductionmentioning

confidence: 99%

Genetic profile and association of candidate gene polymorphism with productivity of Kalmyk cattle

Chimidova,

Ubushieva,

Ubushieva

et al. 2024

BIO Web Conf.

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“…Molecular markers can give a general picture of the genetic makeup of a population by, among other things, identifying the key genes affecting crucial characteristics like growth traits. Improving the productivity of local swamp buffalo growth traits requires the exploration of genetic polymorphisms in growth gene families including among others GH (Growth Hormone) [4][5][6], GHRH (Growth Hormone Releasing Hormone) [6,7]; and PIT-1 (Pituitary-Specific Transcription Factor 1) [8,9].…”

Section: Introductionmentioning

confidence: 99%

“…Growth hormone or GH is crucial for bodily metabolism and growth, performing a substantial part in the lactation, reproduction, and growth processes [4,9]. The bovine GH gene is located on chromosome 19 in the area of q26-qter bases and has an approximate size of 1800 bp consisting of 5 exons and 4 introns [10].…”

Section: Introductionmentioning

confidence: 99%

GH, GHRH, and PIT Genes Polymorphisms of Local Swamp Buffalo in Pandeglang District, Banten Province

Anggraeni¹,

Thalib²,

Saputra³

2023

Advances in Biological Sciences Research

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The molecular selection of the genes influencing growth qualities can be used to genetically improve the production of native swamp buffaloes. Local swamp buffalo (60 hds.) maintained by smallholders in Pandeglang Regency, Banten Province, were examined for the genetic polymorphism of the growing family (GH, GHRH, and PIT1) genes. By using restriction enzymes of MspI (GH gene), HaeIII (GHRH gene), and HinfI (PIT-1 gene), the genotyping of GH g.1547T>C, GHRH g.4666G>C, and PIT-1g.1256G>A SNPs was found by polymerase chain reaction-restriction fragment polymorphism (PCR-RFLP). Genotyping on the respective GH_g.1547T>C, GHRH_g.4666G>C, and PIT-1_g.1256G>A loci, however, resulted in only one type of genotype i.e. CC, GG, and AA with one type of allele i.e. C, G, and A successively. Therefore, the frequencies were 100% or monomorphic for those genotypes and alleles of each growth gene. Also, the PIC values of each locus were 0.00, as were the heterozygosity observation (Ho) and expectation (He) values. It is possible to suggest increasing the genotype frequency of the SNPs of the relevant growth genes that are favorably correlated with the growth traits and associated economic traits of the observed local swamp buffalo in this area.

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“…GH genes provide the biological effects on individual growth after birth, the rate of growth and milk production 9,10 . GH gene plays an important role in reproduction, embryogenesis, lactation, and growth of pigs 7,11,12 . Injections of pregnant mare serum gonadotropin (PMSG) and human chorionic gonadotropin (hCG), increase production of growth hormone in 7 .…”

Section: Introductionmentioning

confidence: 99%

Philogenic Relationship of Wild Pigs and Local Pig from North Sulawesi Based on the Growth Hormone Gene (GH Gene)

Revolson

Mokosuli

Debby

et al. 2019

MSF

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Growth hormone regulates reproduction and growth in mammals. A study was conducted to obtain the characteristics of the GH gene, in local pigs in North Sulawesi. Pig samples were obtained from traditional farmers, from four districts in North Sulawesi. DNA extraction and purification, using pig pituitary tissue. Amplification of GH gene, performed by PCR method. Visualization of CO1 gene amplikon, performed by electrophoresis technique. Sequencing, conducted through the First BASE Singapore sequencing service. The results show that there is a variation of local pigs CO1 gene in North Sulawesi. Variations are also found in the amino acid sequence encoded by the GH gene. Knowledge of the characteristics of local pig gh gene, the basics of selection of local pigs superior to North Sulawesi. Key words : growth hormone gen, local pigs, Sulawesi Utara Abstrak Gen growth hormone meregulasi reproduksi dan pertumbuhan pada mamalia. Telah dilaksanakan penelitian yang bertujuan untuk mendapatkan karakteristik gen GH pada babi lokal di Sulawesi Utara. Sampel babi diperoleh dari peternak tradisonal dari empat kabupaten di Sulawesi Utara. Ekstraksi dan purifikasi DNA menggunakan jaringan hipofisis babi. Amplifikasi gen GH menggunakan metode PCR. Visualisasi amplikon gen CO1 dilakukan dengan teknik elektroforesis. Sekuensing dilakukan melalui jasa layanan sekuensing First BASE Singapura. Hasil penelitian menunjukkan bahwa terdapat variasi gen CO1 babi lokal di Sulawesi Utara. Variasi juga ditemukan pada urutan asam amino yang dikode oleh gen GH. Diketahuinya karakteristik gen GH babi lokal, menjadi dasar seleksi babi lokal unggul Sulawesi Utara.

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Genetic Polymorphisms of α-lactalbumin and β-lactoglobulin in South Anatolian and East Anatolian Red Cattle

Cited by 6 publications

References 25 publications

Genetic profile and association of candidate gene polymorphism with productivity of Kalmyk cattle

Genetic profile and association of candidate gene polymorphism with productivity of Kalmyk cattle

GH, GHRH, and PIT Genes Polymorphisms of Local Swamp Buffalo in Pandeglang District, Banten Province

Philogenic Relationship of Wild Pigs and Local Pig from North Sulawesi Based on the Growth Hormone Gene (GH Gene)

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