Genetic markers for improving farm animals

Deb, Rajib; Mukhopadhyay, Chandra Sekhar; Sengar, Gyanendra Singh; Cruz, Alex Silva da; Silva, Danilo Conrado; Pinto, Irene Plaza; Minasi, Lysa Bernardes; Costa, Emília Oliveira Alves; Cruz, Aparecido D. da

doi:10.1016/b978-0-12-816352-8.00004-7

Cited by 4 publications

(3 citation statements)

References 132 publications

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“…The application of MAS in reproduction has witnessed notable enhancements through technological and methodological advancements. High-throughput genotyping platforms, such as SNP arrays and next-generation sequencing, have emerged as crucial tools, enabling the rapid and cost-effective genotyping of animals on a large scale [7]. These developments have substantially increased the number of markers that can be analyzed, providing breeders with a more comprehensive understanding of an animal's genetic makeup.…”

Section: Advancements In Technology and Techniquesmentioning

confidence: 99%

“…Marker-assisted selection in reproduction enables the early selection of animals with desired traits, leading to more efficient breeding programs and a reduction in the generation interval. Moreover, it paved the way for genomic selection, an advanced approach that utilizes genome-wide markers to estimate breeding values and predict the genetic potential of animals [7,8].…”

Section: Introductionmentioning

confidence: 99%

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Overview of Marker-assisted Selection in Animal Breeding

Sharma,

Doultani,

Hadiya

et al. 2024

JABB

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Marker-assisted selection (MAS) in animal breeding has undergone transformative advancements, reshaping genetic improvement and reproductive traits in livestock and expanding into new domains. From its inception in the late 20th century to current developments, MAS has evolved dynamically through the integration of genomic technologies, sophisticated statistical models, and innovative gene editing techniques. These advancements have significantly enhanced the precision and impact of MAS, revolutionizing genetic improvement and reproductive performance. By synergizing MAS with cutting-edge technologies, the collective aim is to optimize reproductive performance and genetic potential, fostering a sustainable and productive future for livestock breeding and beyond. The genetic markers, typically DNA sequences or genes linked to specific traits, revolutionized animal breeding by enabling the identification of animals carrying favorable genetic variants without the need for resource-intensive phenotypic evaluations. Marker-assisted selection in reproduction also laid the foundation for genomic selection, an advanced approach utilizing genome-wide markers to estimate breeding values and predict genetic potential. This comprehensive review encapsulates the journey of MAS, emphasizing its historical significance, current advancements, and promising future trajectories, showcasing its pivotal role in shaping the landscape of animal breeding and reproductive science.

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Section: Advancements In Technology and Techniquesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Overview of Marker-assisted Selection in Animal Breeding

Sharma,

Doultani,

Hadiya

et al. 2024

JABB

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“…Growth hormone gene (somatotropin, somatotropic hormone, GH) -one of the promising candidate genes, controlling protein synthesis. somatotropin -the main hypophysic hormone, has a wide range of biological effects and significantly affects all the body cells [16].…”

Section: Introductionmentioning

confidence: 99%

Features of polymorphism of calpastatin and somatotropin genes in young sheep, obtained from crossing ewes of Kalmyk fat-rumped sheeps and dorper rams

et al. 2020

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The article presents the study of polymorphism of the CAST and GH genes, which determine the features of the manifestation of the productive and biological characteristics of sheep with ½ Kalmyk + ½ Dorper blood system. Calpastatin gene polymorphism represented by alleles M and N, whose frequency was 0,65 and 0,35; genotypes MM, MN – 30 and 70% accordingly. The desired NN genotype has not been identified. A relatively uniform incidence of allele N (0,35) CAST gene and B (0,40) GH was established, what contributed to an almost equal distribution of allele frequencies М (0,65) and А (0,60) genes of calpastatin and somatotropin accordingly. The frequency of heterozygous genotypes occurrence by CAST gene composed 0,7. By GH gene the following distribution of genotype frequencies is observed. Frequency of occurrence homozygous АА and heterozygous AB genotypes was equal to and is 0,4, wherein the frequency of occurrence advised homozygous ВВ genotype was 0,2. Among the animals studied, sheep with a complex genotype are most common CASTMN GHAB (40 %). The amount of percent CASTMM GHAA and CASTMN GHAA is in 22,2%. 10% is for genotypes CASTMM GHBB and CASTMN GHBB.

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Molecular detected of heat shock protein70 gene in Layer hens (Lohmann breed)

Habib

Karomy

Gheni

et al. 2020

IOP Conf. Ser.: Mater. Sci. Eng.

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The polymorphisms of the hsp70 gene have been associated with diverse resistance of heat stress in hens. The aim of the current study was to explore the genetic variation of the hsp70 gene in Layer hens that bred in Iraq. One hundred-fifty Lohmann breed hens aged 12 months were used in this study. Blood samples were collected during the period from 1st September to 31st December 2018 and examined for detection the polymorphism of hsp70 gene. We have detected four main polymorphisms groups in the coding region of hsp70 gene among these layer hens. A significant association between the silent and the missense mutations with the polymorphisms of hsp70 gene in Layer hens was found. There was a high homology of the hsp70 gene sequences that obtained from our local layer hens with the related sequences obtained from different hottest and coldest areas. In conclusion, this study demonstrates that the different mutations (silent and missense) in the coding region of the hsp70 gene of these local Layer hens predict improve birds’ability to the tolerance of stress conditions, and highlights the need of further investigations.

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Genetic markers for improving farm animals

Cited by 4 publications

References 132 publications

Overview of Marker-assisted Selection in Animal Breeding

Overview of Marker-assisted Selection in Animal Breeding

Features of polymorphism of calpastatin and somatotropin genes in young sheep, obtained from crossing ewes of Kalmyk fat-rumped sheeps and dorper rams

Molecular detected of heat shock protein70 gene in Layer hens (Lohmann breed)

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