GC-MS Analysis of Phytocomponents in the Various Extracts of Shorea robusta Gaertn F.

Sushma, Vashisht; Pal, Singh Manish; Chawla, Viney

doi:10.25258/phyto.v9i6.8179

Cited by 9 publications

(14 citation statements)

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“… 53 , 54 Additionally, Ursa-9(11), 12-dien-3-one, a triterpenoid, present in X. spekei extract, has also been shown to possess antioxidant activities. 55 …”

Section: Discussionmentioning

confidence: 99%

“…53,54 Additionally, Ursa-9(11), 12-dien-3-one, a triterpenoid, present in X. spekei extract, has also been shown to possess antioxidant activities. 55 Hexadecane, a hydrocarbon found in X. spekei extract, has been shown to possess antioxidant effects. 56 Octadecane, another hydrocarbon, present in G. tembensis leaf extract, has antioxidant effects.…”

Section: Discussionmentioning

confidence: 99%

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Quantitative Phytochemical Profile and In Vitro Antioxidant Properties of Ethyl Acetate Extracts of Xerophyta spekei (Baker) and Grewia tembensis (Fresen)

Nyalo

Omwenga

Ngugi

2023

J Evid Based Complementary Altern Med

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Overproduction of free radicals in excess of antioxidants leads to oxidative stress which can cause harm to the body. Conventional antioxidants have drawbacks and are believed to be carcinogenic. The present study seeked to confirm folklore use and validate the antioxidant potentials of Grewia tembensis and Xerophyta spekei which have been widely used in the Mbeere community as medicinal plants. Antioxidant properties were determined through scavenging effects of diphenyl-1-picrylhydrazyl (DPPH) and hydrogen peroxide radicals as well as iron chelating effects. The data obtained was assayed in comparison to the standards (Ascorbic acid and EDTA). Ascorbic acid had a significantly greater DPPH radical scavenging property with an inhibitory concentration (IC50) value of 20.54 ± 2.24 µg/mL in comparison to the plant extracts, which had IC50 values of 33.00 ± 1.47 µg/mL, 69.66 ± 1.01 µg/mL and 86.88 ± 2.64 µg/mL for X. spekei, G. tembensis leaf and G. tembensis stem bark extracts, respectively. EDTA demonstrated a significantly greater iron chelating effect having a significantly lesser IC50 value of 25.05 ± 0.79 µg/mL as opposed to 43.56 ± 0.46 µg/mL, 89.78 ± 0.55 µg/mL, and 120.70 ± 0.71 µg/mL for X. spekei, G. tembensis leaf, and G. tembensis stem bark extracts respectively. Additionally, ascorbic acid also exhibited stronger hydrogen peroxide radical scavenging effect than the studied extracts. Generally, X. spekei extract had higher antioxidant activities as compared to both the leaf and stem bark extracts of G. tembensis. The phytochemical screening demonstrated the presence of secondary metabolites associated with antioxidant properties. The present study therefore, recommends ethno medicinal and therapeutic use of G. tembensis and X. spekei in the treatment and management of oxidative stress related infections.

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“… 53 , 54 Additionally, Ursa-9(11), 12-dien-3-one, a triterpenoid, present in X. spekei extract, has also been shown to possess antioxidant activities. 55 …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Quantitative Phytochemical Profile and In Vitro Antioxidant Properties of Ethyl Acetate Extracts of Xerophyta spekei (Baker) and Grewia tembensis (Fresen)

Nyalo

Omwenga

Ngugi

2023

J Evid Based Complementary Altern Med

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“…The GC–MS analysis of the LGBME also supported the current findings. The identified compounds of bark extract (LGBME)-caryophyllene and 9-Octadecenoic acid (Z)-methyl ester (oleic acid methyl ester) are known for their antioxidant properties [ 29 , 30 , 31 , 32 , 33 ].…”

Section: Discussionmentioning

confidence: 99%

Phytochemical Analysis and Understanding the Antioxidant and Anticancer Properties of Methanol Extract from Litsea glutinosa: In Vitro and In Vivo Studies

et al. 2022

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Litsea glutinosa (L. glutinosa) is considered an evidence-based medicinal plant for the treatment of cancer, the leading cause of death worldwide. In our study, the in vitro antioxidant and in vivo anticancer properties of an essential ethno-medicinal plant, L. glutinosa, were examined using non-toxic doses and a phytochemical analysis was executed using gas-chromatography–mass-spectrometry. The in vitro antioxidant study of the L. glutinosa methanolic extract (LGBME) revealed a concentration-dependent antioxidant property. The bark extract showed promising antioxidant effects in the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) assay. The strongest antioxidant activity was demonstrated at the maximum concentration (50 µg/mL). The IC50 values of the LGBME and BHT were 5.51 and 5.01 µg/mL, respectively. At the same concentration, the total antioxidant capacity of the LGBME was 0.161 µg/mL and the ferric reducing antioxidant power assay result of the LGBME was 1.783 µg/mL. In the cytotoxicity study, the LD50 of the LGBME and gallic acid were 24.93 µg/mL and 7.23 µg/mL, respectively. In the in vivo anticancer-activity studies, the LGBME, particularly at a dose of 150 mg/kg/bw, showed significant cell-growth inhibition, decreased tumor weight, increased mean survival rate, and upregulated the reduced hematological parameters in EAC (Ehrlich’s ascites carcinoma)-induced Swiss albino mice. The highest cell-growth inhibition, 85.76%, was observed with the dose of 150 mg/kg/bw. Furthermore, the upregulation of pro-apoptotic genes (p53, Bax) and the downregulation of anti-apoptotic Bcl-2 were observed. In conclusion, LGBME extract has several bioactive phytoconstituents, which confirms the antioxidant and anticancer properties of L. glutinosa.

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“…GC-MS is a technology that is used to identify Phytocompounds (Shibula et al, 2015). GC-MS has identified fiftytwo compounds from the methanolic fruit extract of C. wightii in this study.…”

Section: Gas Chromatography-mass Spectroscopy Analysismentioning

confidence: 94%

Commiphora Wightii: A Natural Approach in Control of Urinary Tract Infections

Mishra¹,

Jain²,

Suresh³

et al. 2023

IJARe

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Background: To investigate the extracts of Commiphora wightii for the presence of phytoconstituents and screen anti-microbial activity against dominant UTI pathogens. GC-MS and FTIR are used for the identification of functional groups of the bioactive compounds. Methods: Five different solvents were screened for extraction of compounds from the powdered plant at temperatures ranging from 60 to 80 upto 72 hours. These extracts were used for preliminary phytochemical and antimicrobial analyses. Functional groups were identified by using Fourier-Transform Infrared Spectrophotometer scanning from 450 to 4000 cm-1 and a 4 cm-1 resolution. The existence of the major compound with the most promising antimicrobial activities was discovered utilising GC-MS analysis. Result: The results revealed that the methanolic extract of Commiphora wightii displayed significant glycosides and flavonoids. Fifty-two functional compounds were identified using GC-MS and FTIR.

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GC-MS Analysis of Phytocomponents in the Various Extracts of Shorea robusta Gaertn F.

Cited by 9 publications

References 0 publications

Quantitative Phytochemical Profile and In Vitro Antioxidant Properties of Ethyl Acetate Extracts of Xerophyta spekei (Baker) and Grewia tembensis (Fresen)

Quantitative Phytochemical Profile and In Vitro Antioxidant Properties of Ethyl Acetate Extracts of Xerophyta spekei (Baker) and Grewia tembensis (Fresen)

Phytochemical Analysis and Understanding the Antioxidant and Anticancer Properties of Methanol Extract from Litsea glutinosa: In Vitro and In Vivo Studies

Commiphora Wightii: A Natural Approach in Control of Urinary Tract Infections

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