Frequency of Uveitis in the Central Tokyo Area (2010–2012)

Nakahara, Hisae; Kaburaki, Toshikatsu; Tanaka, Rie; Takamoto, Masao; Ohtomo, Kazuyoshi; Karakawa, Ayako; Komae, Keiko; Okinaga, Kimiko; Matsuda, Junko; Fujino, Yujiro

doi:10.3109/09273948.2015.1133840

Cited by 22 publications

(13 citation statements)

References 23 publications

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“…Consequently, the number of definite diagnoses has been gradually increasing [ 2 ]. However, a definite diagnosis can still not be reached in approximately 30–40% of patients newly diagnosed with uveitis [ 2 , 4 , 5 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

Epidemiology of uveitis (2013–2015) and changes in the patterns of uveitis (2004–2015) in the central Tokyo area: a retrospective study

et al. 2018

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BackgroundThe distribution of uveitis varies with genetic, ethnic, geographic, environmental, and lifestyle factors. Epidemiological information about the patterns of uveitis is useful when an ophthalmologist considers the diagnosis of uveitis. Therefore, it is important to identify the causes of uveitis over the years in different regions. The purposes of this study were to characterize the uveitis patients who first arrived at the University of Tokyo Hospital in 2013–2015, and to analyze the changes in the patterns of uveitis from 2004 to 2012 to 2013–2015.MethodsWe retrospectively identified 750 newly arrived patients with uveitis who visited the Uveitis Clinic in the University of Tokyo Hospital between January 2013 and December 2015, using clinical records. We extracted data on patient age, sex, diagnosis, anatomic location of inflammation, laboratory test results of blood and urine, and chest X-ray and fluorescein fundus angiography findings for each patient. In addition, we compared these data with those from 2004 to 2012 to analyze the changes in the patterns of uveitis.ResultsA definite diagnosis was established in 445 patients (59.3%). The most common diagnoses were herpetic iridocyclitis (7.5%), sarcoidosis (6.1%), Behçet’s disease (4.4%), Vogt–Koyanagi–Harada disease (4.1%), and intraocular lymphoma (4.1%). The most frequent unclassified type of uveitis was suspected sarcoidosis (22.3%). Analysis of the changes in the patterns of uveitis in the central Tokyo area from 2004 to 2012 to 2013–2015 revealed notable increasing trends of herpetic iridocyclitis and intraocular lymphoma, and increasing trends of bacterial endophthalmitis, fungal endophthalmitis, and juvenile chronic iridocyclitis. In contrast, the frequency of sarcoidosis, Behçet’s disease, and Vogt–Koyanagi–Harada disease decreased.ConclusionsThe patterns of uveitis changed considerably from 2004 to 2012 to 2013–2015. Continuous investigations about the epidemiology of uveitis are needed to diagnose uveitis more accurately.

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Section: Introductionmentioning

confidence: 99%

Epidemiology of uveitis (2013–2015) and changes in the patterns of uveitis (2004–2015) in the central Tokyo area: a retrospective study

et al. 2018

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“…Table 3 shows the frequencies of TOP4 as percentages and order in the reports from other facilities 5,7,9,10–14. Several reports from Japan, as well as from other parts of Asia, and from Europe and North America are shown.…”

Section: Resultsmentioning

confidence: 99%

Uveitis incidence in Jichi Medical University Hospital, Japan, during 2011-2015

Takahashi

Yoshida

Inoda

et al. 2017

OPTH

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PurposeTo investigate uveitis incidence of new patients who visited Jichi Medical University Hospital, Tochigi, north of Tokyo, during 2011–2015, and to compare the results with previously reported data from other facilities.MethodsWe retrospectively analyzed clinical records of new patients with uveitis from April 2011 to March 2015 and compared the uveitis incidence with those from other hospitals.ResultsA total of 502 patients were enrolled in the study; definite diagnoses were made in 262 patients (52.2%). The top 4 diseases were sarcoidosis, 47 patients (9.4%); Vogt–Koyanagi–Harada (VKH) disease, 35 patients (7.0%); herpetic iritis, 29 patients (5.8%); and Behçet’s disease, 21 patients (4.2%).ConclusionThe most commonly diagnosed diseases in our study were sarcoidosis, VKH disease, herpetic iritis, and Behçet’s disease. Compared with the latest nationwide survey in Japan, our results showed similar trends.

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“…For example, compared with patients before 2010, recent patients in Singapore showed a higher percentage of infectious uveitis [26]. Studies in Japan have revealed that 35-63% of uveitis cases were noninfectious, and 31-50% were idiopathic [7,[27][28][29][30][31][32]. These studies have also demonstrated that the patterns and specific entities of uveitis, including endophthalmitis, sarcoidosis, Bechet's disease, VKH disease, and anterior uveitis, have changed with time.…”

Section: Epidemiology and Distribution Of Etiologiesmentioning

confidence: 99%

“…A study from Tokyo University Hospital indicated a decrease in patients with VKH disease from 6.3% in 2004-2006 to 4% in 2010-2012. The authors attributed this finding to the increase in optical coherence tomography in communitybased clinics, making diagnosis easier and allowing more patients to be treated rather than referred to university hospital-based clinics [31]. Gender predilection of VKH disease seems to vary globally.…”

Section: Epidemiologymentioning

confidence: 99%

Noninfectious uveitis in the Asia–Pacific region

Hsu

Huang

Tao

et al. 2018

Eye

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Uveitis is a sight-threatening disease. Up to 35% of patients may have impaired vision. Inflammation of the uvea tissue has more than 60 etiologies. Previous reports have shown that 20-40% of uveitis cases were noninfectious. Some of them may be associated with systemic rheumatological and autoimmune diseases but some may affect the eyes only. The epidemiology and clinical situations of some specific uveitis entities vary worldwide because they are influenced by genetic, ethnic, environmental, and socioeconomic factors. The Asia-Pacific region comprises more than 30 countries. Epidemiology and patterns of uveitis vary greatly in this region. However, some uveitis entities, such as Behcet's disease, sarcoidosis, and Vogt-Koyanagi-Harada disease, are more common in this region. Many studies on the epidemiology, risk factors, and immune pathogenesis of this disease have been conducted. In this article, we review the epidemiology of noninfectious uveitis and special situations of these three uveitis entities in the Asia-Pacific region.

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Frequency of Uveitis in the Central Tokyo Area (2010–2012)

Cited by 22 publications

References 23 publications

Epidemiology of uveitis (2013–2015) and changes in the patterns of uveitis (2004–2015) in the central Tokyo area: a retrospective study

Epidemiology of uveitis (2013–2015) and changes in the patterns of uveitis (2004–2015) in the central Tokyo area: a retrospective study

Uveitis incidence in Jichi Medical University Hospital, Japan, during 2011-2015

Noninfectious uveitis in the Asia–Pacific region

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