Frequency of Intestinal Parasites in Patients with Diabetes Mellitus Compared with Healthy Controls in Fasa, Fars Province, Iran, 2018

Abstract

Background: Parasitic diseases are medically important, especially among immunocompromised patients. Recently, diabetes mellitus (DM) has become one of the most important clinical diseases, and the combination of this disease with parasitic infections can result in serious consequences. Objectives: The aim of this study was to evaluate the infection of intestinal parasites in patients with DM and compare them with healthy individuals in Fasa city and surrounding health centers. Methods: In this case-control study a total of 501 patients and healthy individuals (254 patients with DM and 247 healthy controls) referred to health centers in Fasa, Fars province. Fecal specimens of all of these individuals were collected in a special container. These specimens were investigated using direct smear, concentration method, acid-fast and trichrome staining, agar plate cultivation, and Baermann technique. Results: In this study, 254 diabetic patients (50.7%) and 247 (49.3%) healthy controls were included. The age range of these people was between 25 to 89 years old, with an average age of 57.7 ± 10.7. Our findings revealed that the frequency of intestinal parasites in the control group (18.6%) is higher than the patient group (12.6%). Conclusions: Although the frequency of intestinal parasites in the control group was higher than the patient group, this does not reduce the importance of preventative programs for these patients. Considering the significant effect of unpurified water on intestinal parasites, it is better to consider this issue more in health programs.

Intestinal parasites and diabetes: A systematic review and meta-analysis

“…[ 44 ] 2015 Eastern Mediterranean Iran Formalin-ether/acid-fast and trichrome staining 118 31 118 8 Poorkhosravani et al. [ 45 ] 2019 Eastern Mediterranean Iran Baermann and trichrome staining 254 32 247 46 Tangi et al. [ 46 ] 2016 African region Cameroon Formalin-ether/acid-fast staining 150 15 85 20 Nazligul et al.…”

Investigation of Blastocystis hominis Frequency in Patients with Diabetes by Microscopy and Conventional PCR Methods

“…Studies were conducted to compare the frequency of B. hominis in diabetic patients and healthy control groups. In these studies, in patients with diabetes and those in the control groups (two groups) the parasite was determined, respectively, at rates of 9.1% and 10.1% by Poorkhosravani et al ( 11 ), 2.7% and 1.2% by Tangi et al ( 12 ), 9.3% and 2.5% ( P <0.05) by Mohtashamipour et al ( 13 ), 42% and 4% ( P <0.05) by Aourarh et al ( 14 ), 24.4% and 23.2% by Bafghi et al ( 15 ), 12.3% and 9% by Popruk et al ( 16 ), 65% and 25% by Ibrahim et al ( 17 ), as well as 12.1% and 7.9% by Melo et al ( 18 ).…”

Effects of Lactobacilli acidophilus and/or spiramycin as an adjunct in toxoplasmosis infection challenged with diabetes

“…Interestingly, the gastrointestinal manifestations in this risk group of patients are usually attributed to autonomic neuropathy common in diabetes ( Bytzer et al, 2001 ) ignoring the role of infectious diseases. Indeed, prior studies underscored parasitic misdiagnosis in diabetic children ( Rady et al, 2019 ) and adult patients ( Poorkhosravani et al, 2019 ). Therefore, the figure of the inflammatory cascade in T. gondii infection challenged with DM appeared to be an interesting research point ( Akinbo et al, 2013 ).…”