Formulation and Evaluation of Solid Lipid Nanoparticles of Ramipril

Porpatham, E.; Sathali, A. Abdul Hasan

doi:10.4103/0975-1483.83765

Cited by 175 publications

(128 citation statements)

References 9 publications

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“…Nanotechnology is the cure-all medicine that we have been searching for years and it turns out that it's not actually a "medicine" at all!. The efficiency of Nanotechnology implemented in complicated, chronic untreated heart 3 and respiratory diseases 4 and to focus on diabetes 5 , cancer 6 and birth defects etc.…”

Section: Referencesmentioning

confidence: 99%

The Bleeding Edge-Nanotechnology in medical sciences

Venugopal¹

2016

JYP

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REFERENCESWe have been hearing about nanotechnology for a long time back in both science fiction and in the media, but that not much has come of it so far. However, new platforms of nanotech-based treatments are on the horizon, and are ready to change the world of medicine. Basically nanotechnology is the field that works at the nano scale range (One nanometer is one billionth of a meter).1 Nanomedicine is linked nanotechnology for medical purposes. They are some other terms including biomedical nanotechnology, bionanotechnology and nanobiotechnology. The potency of nanotechnology took a long time to show its face, but it is finally starting to arrive in the form of sophisticated medical interference that will proudly change the nature of healthcare in the near future. In the medicine technology, one of the biggest issues is our inability to correctly target interventions. Nanotechnology offers a way to direct interposition in the human body, potentially on a level of particular cells, using smart operating elements that are so small that they do not physically interfere with normal body function.2 Fine fingers do less damage, and machines smaller than the micro capillary in the body can go everywhere that blood goes. If they can be made smart enough, such nanomedical devices can aptly choose where and how to intervene. Obviously, more will be possible when engineers can build robots that have more refined behaviours (like the ability to work under their own power), but even relatively primeval nanomachines of today have a lot of value. Nanotechnology will play a vital role on all of our lives in the very near future in everything ranging from clothes to medicine. Below are a few things that will benefit your future based on the wondrous possibilities of nanotechnology. Nanotechnology is the cure-all medicine that we have been searching for years and it turns out that it's not actually a "medicine" at all!. The efficiency of Nanotechnology implemented in complicated, chronic untreated heart 3 and respiratory diseases 4 and to focus on diabetes 5 , cancer 6 and birth defects etc.Many people are not capable of breeding simply because their bodies are not good hosts to a suitable environment. With the aid of nanotechnology, these little nanobots will quickly go to work at reconstructing your genitals and other reproductive characters so you'll once again be able to carry your own children. That means you don't have to adopt children, because you can now have your very own child that has your own genes. In the nanotechnology, tiny computers called nanites come together to work simultaneously throughout whatever object they are inserted into in order to perform amazing tasks at the molecular level and these really cool structures called nanotubes (carbon nanotubes) that are just as stiff as diamonds and one hundred times stronger than steel, yet they're six times lighter than steel. Nanomedicine will be able to move throughout your body and locate any and all cancer cells and not only label them so that doctors will ...

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Section: Referencesmentioning

confidence: 99%

The Bleeding Edge-Nanotechnology in medical sciences

Venugopal¹

2016

JYP

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“…Many heat-sensitive drugs can be incorporated into lipid nanoparticles using this technique, which is more suitable for hydrophilic drugs [270,290].…”

Section: Cold Homogenizationmentioning

confidence: 99%

“…After SLNs are characterized, the third most important step is their application according to the desired properties. Different applications have been studied in the literature, especially in cancer treatment: (i) chemotherapeutic drugs incorporated into SLNs to eliminate their disadvantages and overcome MDR, (ii) gene therapy (delivery of peptides, genes, miRNA, siRNA into cells), (iii) drug targeting, new adjuvants for vaccines, treatment of infectious diseases, cosmetic and dermatological preparations and agricultural applications [268][269][270][271][272][273][274][275][276][277][278][279][280][281][282][283]. Figure 5.…”

Section: Advantages Of Sln Disadvantage Of Slnmentioning

confidence: 99%

Nano-based drug delivery system

Eskiler¹,

Dıkmen²,

Genc³

2015

Nano Based Drug Delivery

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“…They have good compatibility and low toxicity and are physically stable. Lipophilic drugs are better delivered using solid lipid nanoparticles (Ekambaram, Sathali, Priyanka, 2012;Pragati et al, 2009).…”

Section: Solid Lipid Nanoparticlesmentioning

confidence: 99%

A review of nanotechnology with an emphasis on Nanoplex

Kadam

Shendge

Pande

2015

Braz. J. Pharm. Sci.

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The use of nanotechnology based on the development and fabrication of nanostructures is one approach that has been employed to overcome the challenges involved with conventional drug delivery systems. Formulating Nanoplex is the new trend in nanotechnology. A nanoplex is a complex formed by a drug nanoparticle with an oppositely charged polyelectrolyte. Both cationic and anionic drugs form complexes with oppositely charged polyelectrolytes. Compared with other nanostructures, the yield of Nanoplex is greater and the complexation efficiency is better. Nanoplex are also easier to prepare. Nanoplex formulation is characterized through the production yield, complexation efficiency, drug loading, particle size and zeta potential using scanning electron microscopy, differential scanning calorimetry, X-ray diffraction and dialysis studies. Nanoplex have wide-ranging applications in different fields such as cancer therapy, gene drug delivery, drug delivery to the brain and protein and peptide drug delivery.Uniterms: Nanotechnology. Nanoplex/formulation. Nanoplex/characterization. Nanoplex/applications O uso da nanotecnologia baseada no desenvolvimento e na fabricação de nanoestruturas é uma abordagem que tem sido empregada para superar os desafios envolvidos nos sistemas de liberação de fármacos convencionais. A formulação de nanoplexos é a nova tendência na nanotecnologia. Um nanoplexo é um complexo formado pela nanopartícula do fármaco com poplieletrólito de carga oposta. Tanto fármacos catiônicos quanto aniônicos formam complexos com polieletrólitos opostamente carregados. Comparado com outras nanoestruturas, o rendimento dos nanoplexos é maior e a eficiência de complexação é melhor. Nanoplexos são, também. De mais fácil preparação. A formulação de nanoplexo é caracterizada pelo rendimento de produção, eficiência de complexação, carga do fármaco, tamanho de partícula e potencial zeta, utilizando microscopia eletrônica de varredura, calorimetria exploratória diferencial, difração de raios X e estudos de diálise. Os nanoplexos têm aplicações amplas em diferentes campos, como terapia antineoplásica, liberação em terapia gênica, liberação cerebral de fármaco, liberação de fármacos protéicos e peptídicos.Unitermos: Nanotecnologia. Nanoplexos/formulação. Nanoplexos/caracterização. Nanoplexos/ aplicações.

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Formulation and Evaluation of Solid Lipid Nanoparticles of Ramipril

Cited by 175 publications

References 9 publications

The Bleeding Edge-Nanotechnology in medical sciences

The Bleeding Edge-Nanotechnology in medical sciences

Nano-based drug delivery system

A review of nanotechnology with an emphasis on Nanoplex

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