Fixing the direction of droplets in a bifurcating microfluidic junction

Abstract

We present a novel type of microfluidic bifurcating junctions which fixes the droplet's route. Unlike in regular junctions, where a droplet chooses one of two outputs depending on the (often instantaneous) flow distribution, our modifications direct droplets only to one preferred outlet. As we show, this solution works properly regardless of the variations of flow distribution in a wide range of its amplitude. Such modified junctions allow for the encoding of the droplet's traffic in the geometry of the device. We compare in a series of experiments different junctions having channels of uniform square cross section. Our observations revealed that a small, local modification of the junction in the form of an additional shallow slit imposes a significant consequence for the flow of droplets at an entire microfluidic network's scale. Another interesting and helpful feature of these new junctions is that they keep the integrity of long droplets, unlike regular junctions, which tend to split long droplets. Our experimental investigations revealed a complex transformation of the long droplet during its transfer through the modified junction. We show that this transformation resembles the Baker's transform and can be used for the enhancement of mixing inside the droplets. Finally, we show two examples of microfluidic devices where the deterministic character of these modified junctions is utilized to obtain new, non-trivial functionalities. This approach can be used for the engineering of microfluidic devices with embedded procedures replacing active elements like valves or magnetic/electric fields.

Integration of capillary–hydrodynamic logic circuitries for built-in control over multiple droplets in microfluidic networks

“…previous work, 30 a modified junction with a slit can fix the custom direction of a droplet regardless of the resistances of the branches. Such a solution provides a higher degree of control, allowing the direction of the first droplet to the long branch and swapping functionalities between loop-branches.…”