Fine needle aspiration cytology in the diagnosis of lymph nodes: Correlation with histopathological diagnosis

Altınboğa, Ayşegül Aksoy

doi:10.14744/scie.2019.14622

Cited by 6 publications

(10 citation statements)

References 22 publications

(24 reference statements)

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“…The success rate of FNAB has been reported to vary between 38% and 88.8% in the identification of the correct subtype of lymphoma 33 . However, some studies in the literature have reported a lower sensitivity (72%) for FNAB in neck lymphomas, and open surgical biopsy is recommended 32 . In our current study, the diagnosis of lymphoma was made by clinical and radiological confirmation of the presence of atypical lymphoid cells according to the FNAB result.…”

Section: Discussionmentioning

confidence: 76%

“… 33 However, some studies in the literature have reported a lower sensitivity (72%) for FNAB in neck lymphomas, and open surgical biopsy is recommended. 32 In our current study, the diagnosis of lymphoma was made by clinical and radiological confirmation of the presence of atypical lymphoid cells according to the FNAB result. In general, the sensitivity of FNAB was high (91.5%), consistent with the literature.…”

Section: Discussionmentioning

confidence: 97%

“…There are many studies investigating the effectiveness of FNAB in cervical lymph nodes. Although it is an accepted technique with a sensitivity of over 90% in infectious/inflammatory diseases and metastatic disease, its place in the diagnosis of lymphoproliferative diseases is controversial 32 . The success rate of FNAB has been reported to vary between 38% and 88.8% in the identification of the correct subtype of lymphoma 33 .…”

Section: Discussionmentioning

confidence: 99%

“…Although it is an accepted technique with a sensitivity of over 90% in infectious/inflammatory diseases and metastatic disease, its place in the diagnosis of lymphoproliferative diseases is controversial. 32 The success rate of FNAB has been reported to vary between 38% and 88.8% in the identification of the correct subtype of lymphoma. 33 However, some studies in the literature have reported a lower sensitivity (72%) for FNAB in neck lymphomas, and open surgical biopsy is recommended.…”

Section: Discussionmentioning

confidence: 99%

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Tuberculous and non‐tuberculous cervical lymphadenopathy incidence and distribution in Somalia from 2016 to 2020: A review of 241 cases

Tahtabaşı

Şahiner

2022

World j. otorhinolaryngol.-head neck surg.

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Objective To determine the incidence of tuberculous lymphadenitis (TBL) and other pathologies in cervical lymphadenopathies in Somalia and accompanying radiological findings. Methods In this hospital‐based retrospective study, the demographic characteristics, pathology results and radiological findings of 263 patients who underwent ultrasound (US)‐guided cervical lymph node biopsy between January 2016 and February 2020 were analyzed. Results Of 241 patients 118 men and 123 women (mean age 27.9 ± 18.1 years) included in the study, 46.1% (n = 111) were diagnosed as necrotizing granulomatous lymphadenitis (caseified, consistent with TBL) and 21.6% (n = 12, atypical lymphoid cells and n = 40, metastases) as malignancy. The most common type of metastasis was squamous cell cancer (n = 31), and the primary source of most of them was esophageal cancer (16/31, 51.6%). The age of patients with TBL was significantly lower than that of non‐TBL (21.9 ± 14.6 vs. 41.9 ± 24.6, P = 0.003) and the incidence of TBL in pediatric patients was statistically higher (58.0% vs. 21.5%, P = 0.019). The rate of patients with TBL being localized at level 4 and level 5 was significantly more than non‐TBL patients (18.0% vs. 10.0% and 23.4% vs. 10.8%, respectively, P = 0.01). Half of patients with TBL who have chest radiography had pathological findings; consolidation and bronchopneumonia were present in 52.6% of them. There were 2 patients with paravertebral abscess and one patient with gastrointestinal tuberculosis. Conclusion In Somalia, in the presence of cervical lymphadenopathy, after diagnosis by using US‐guided biopsy; primarily considering of TBL and malignancy, thoracic involvement should be investigated, and esophageal carcinoma must be excluded in terms of metastatic lymph node.

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Section: Discussionmentioning

confidence: 76%

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Tuberculous and non‐tuberculous cervical lymphadenopathy incidence and distribution in Somalia from 2016 to 2020: A review of 241 cases

Tahtabaşı

Şahiner

2022

World j. otorhinolaryngol.-head neck surg.

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Section: Introductionmentioning

confidence: 99%

Cytomorphological study of head and neck lymph node lesions

Keerthana¹,

Begum²,

Siddiqui³

2020

JDPO

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The head and neck area is a complex anatomical structure which includes various nonneoplastic and neoplastic lesions of lymph node, salivary gland, thyroid gland and soft tissue. Fine needle aspiration cytology of head and neck lymph nodes proved useful in separating inflammatory lesions, which do not require surgical excision from cystic and neoplastic lesions with good certainty. Fine needle aspiration cytology (FNAC) is a simple, feasible, cost effective and minimally invasive procedure. But histopathological examination is more valuable for confirmatory diagnosis in suspected lesions. Aim: To assess the utility of FNAC in diagnosis of head and neck lymph node lesions and to establish the diagnostic accuracy of cytology by comparing with the histopathological diagnosis, wherever possible. Materials and Methods: A 6 months retrospective study was done from March 2020 to August 2020 at Khaja Bandanawaz institute of medical sciences on 50 patients presenting with head and neck lymph node enlargement. Result: 50 cases were evaluated by FNAC. In this study out of 34 benign cases, 14 cases were of Reactive lymphadenitis, 17 cases of Granulomatous/Tuberculous lymphadenitis and 3 cases were of Acute suppurative lymphadenitis. Out of 16 malignant cases, 5 cases were of Non Hodgkins lymphoma, 2 cases were of hodgkins lymphoma and 9 cases were of metastatic carcinoma. Conclusion: FNAC has been found to be a satisfactory tool in the diagnosis of tubercular and malignant lymphadenopathy in our study. The lucidity and rapidity of the procedure makes it most appropriate for use on outpatient basis even in peripheral hospitals and dispensaries.

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Comparison of Fine Needle Aspiration Cytology and Histopathology in the diagnosis of lymph node pathologies at health facilities located in Hawassa: A 5-year retrospective study

et al. 2022

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Objective: The aim of this study was to evaluate the performance of Fine Needle Aspiration Cytology in the diagnosis of lymph node pathologies in comparison with Histopathologic examination. Methods: A retrospective health facility-based cross-sectional study was carried out at health facilities located in Hawassa city among 101 patients who had both Fine Needle Aspiration Cytology and Histopathologic examination on the same site from 13 September 2016 to 30 August 2021. Background data were collected using a structured questionnaire and analyzed by SPSS version 20. Results: A total of 3892 patients had Fine Needle Aspiration Cytology for lymphadenopathies within a specified 5-year span, out of which 101 cases had both Fine Needle Aspiration Cytology and Histopathologic examination. The overall sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of fine needle aspiration cytology for the diagnosis of lymphoma were 88.2%, 92%, 91.8%, 88.5%, and 90.1%, respectively. Conclusions: Fine Needle Aspiration Cytology can be recommended for clinically significant lymphadenopathy as a first-line diagnostic test since it is fast, safe, cost-effective, reasonably sensitive, and specific with significant positive and negative predictive values and diagnostic accuracy.

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Fine needle aspiration cytology in the diagnosis of lymph nodes: Correlation with histopathological diagnosis

Cited by 6 publications

References 22 publications

Tuberculous and non‐tuberculous cervical lymphadenopathy incidence and distribution in Somalia from 2016 to 2020: A review of 241 cases

Tuberculous and non‐tuberculous cervical lymphadenopathy incidence and distribution in Somalia from 2016 to 2020: A review of 241 cases

Cytomorphological study of head and neck lymph node lesions

Comparison of Fine Needle Aspiration Cytology and Histopathology in the diagnosis of lymph node pathologies at health facilities located in Hawassa: A 5-year retrospective study

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