Fiber optic immunosensor for polychlorinated biphenyls.

Immunochemical determination of xenobiotics with endocrine disrupting effects

“…The current requirements needed for the analysis of trace substances and pharmaceuticals in food industries and in clinical areas [59] have made of the immunosensors interesting alternatives that may provide fast, highly sensitive, specific, and automated analytical devices, continuous monitoring systems, etc. Although the most well known of these is the glucose sensor and other sensors employed for medical diagnoses, several immunosensors have also been developed for the detection of pesticides [60,61,62] and pollutants [63,64].…”

Development of a Fluorescence Immunoassay for Measurement of Paclitaxel in Human Plasma

“…Many reviews detailing the research and development in the field of optical-based immunoassays have been published (14,15). A number of FIA have been developed for the detection of explosive materials (16), polychlorinated biphenyls (PCBs) (17), and atrazine (18). The configurations employed in these studies included antibody saturated with corresponding fluorescent-labeled antigen immobilized onto either a decladed optical fiber, which is integrated to a fluorometer, or the inside walls of a capillary flow column placed upstream of a fluorescence detector.…”

Biosensors for environmental applications: Future development trends

“…The high toxicity of some PCB congeners represents a risk for public health as these compounds are still present in the environment, even though the production of PCBs has been banned in several countries many years ago. Different biosensor configurations have been designed to determine PCBs in the environment, and these include the DNA biosensor with chronopotentiometric detection [59], and various immunosensors with fluorescence [60], SPR [61], and electrochemical [62] detection principles.…”