2015
DOI: 10.1590/0102-311x00106914
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Fatores associados à não adesão aos antirretrovirais em adultos com AIDS nos seis primeiros meses da terapia em Salvador, Bahia, Brasil

Abstract: O controle da replicação viral é essencial na terapia antirretroviral altamente potente (TARV) e a adesão ao tratamento é o fundamento para esse controle. Fatores individuais e externos influenciam a adesão aos antirretrovirais (ARV). Estudo transversal para investigar fatores associados à não adesão à TARV, em indivíduos com AIDS em Salvador, Bahia, Brasil, com idade ≥ 13 anos e primeira prescrição em 2009. Dados coletados em prontuários e registros da farmácia. Dos 216 pacientes, 65,3% eram homens; idade méd… Show more

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Cited by 75 publications
(101 citation statements)
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References 29 publications
(53 reference statements)
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“…Moreover, the increased time between diagnosis of the HIV infection and AIDS manifestation in addition to the side effects caused by the treatment are important indicators of poor treatment adherence (Silva et al 2015). These are some of the factors that may explain the minimal difference in the average number of T CD4+ lymphocytes and viral load since the start of the treatment (baseline) and after three and six months of treatment in our study.…”
Section: Discussionmentioning
confidence: 71%
“…Moreover, the increased time between diagnosis of the HIV infection and AIDS manifestation in addition to the side effects caused by the treatment are important indicators of poor treatment adherence (Silva et al 2015). These are some of the factors that may explain the minimal difference in the average number of T CD4+ lymphocytes and viral load since the start of the treatment (baseline) and after three and six months of treatment in our study.…”
Section: Discussionmentioning
confidence: 71%
“…The variables related to the sample profile showed statistically significant association were age (p = 0.029) and education (p = 0.043), a result found in studies that assessed adherence to therapy in patients living with HIV, showing that increased age is associated with greater likelihood of following the recommended treatment (16)(17) . A high level of education is generally associated with good adhesion, whereas other studies have found a correlation between high levels of education and access to information (4,15,18) .…”
Section: Discussionmentioning
confidence: 77%
“…Some studies claim that factors such as the difficulty to adjust therapy to the patient's life routine, involving issues such as work, lack of social support, social isolation and side effects due to use of medication, may be related to the difficulty of follow-up, missing scheduled appointments and even abandoning treatment (4,14,17) . The Ministry of Health also states that the non-acceptance of seropositivity, the presence of mental disorders, unsatisfactory relationship with professional health services, negative beliefs and misinformation regarding the treatment, alcohol abuse and abuse of other drugs, lack of human resources, difficulty to find transportation, the stigma related to paternity/maternity of PLWHA, and social exclusion are factors that hinder adherence (4) .…”
Section: Variablesmentioning
confidence: 99%
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“…Torna-se fundamental a identificação de indivíduos que aderem ao tratamento antirretroviral, pois a partir do momento em que há falha na adesão, o sistema imunológico estará vulnerável a danos, que se reflete em baixos níveis de Linfócitos CD4+, que tem como influência a progressão para a AIDS e o desenvolvimento de infecções oportunistas. 27 Portanto, com o reconhecimento da variável uso de antirretroviral, provavelmente, poderia obter-se uma explicação sobre o elevado quantitativo de casos notificado com Aids (91,3%).…”
Section: Resultsunclassified