In this paper, we discuss the use of broadband high frequency electromagnetic waves (RF) to non-destructively identify, classify and characterize performance-limiting defects in emerging nanoelectronic devices. As an illustration, the impact of thermal cycling on the RF signal characteristics (insertion loss (S 21 ) and return loss (S 11 )) is used to infer thermo-mechanical stress-induced defects in metal interconnects. The inferred defects are supported with physical analytical data where possible. In this paper, we discuss the use of broadband radio frequency (RF) to non-destructively identify and characterize performance-limiting defects in emerging nanoelectronic devices. To do this, we reinterpret previously published (mostly from reference 1), and some new data, to demonstrate the utility of RF phase data in failure mode analysis, to detect structural changes in devices, without resorting to the traditional destructive physical analysis.Emerging nanoelectronics are rapidly adapting three dimensional integrated circuits (3D-ICs), enabled by through-silicon vias (TSV), as a strategy to increase performance and functional diversification. However, the introduction of such 3D-ICs to the market has been hindered by reliability challenges such as stress related failures. Specifically, the stress buildup due to mismatch in the coefficient of thermal expansion (CTE) of the materials of construction results in the generation of defects such as cracks, voids, delamination, plastic deformation, substrate warping and buckling.1 These types of damage ultimately lead to open or short circuits in the devices, resulting in catastrophic failure. While metrology for accurate quantification of the impact of stress evolution in interconnect structures is needed, further insights are required to characterize and understand the physical damage stemming from the stress buildup. Microwave (RF)-based metrology tools offer several advantages over the traditional techniques and are uniquely suitable for studying the buried structures and interfaces inherent in such nanoelectronic devices. For example, changes in RF insertion losses offer early prognostics of the onset of failure in ball grid arrays (BGA) subjected to accelerated temperature cycling tests.2,3 RF measurements have also been used to specifically show that leakage conductance increased with the degree of voiding damage in Al and AlCu metal interconnects lines in integrated circuits.3 As well, such high frequency measurements have been used to monitor TSV interconnect performance.