Extraction of lignans from the seed of Schisandra chinensis by supercritical fluid extraction and subsequent separation by supercritical fluid simulated moving bed

Determination of Parameters for the Supercritical Extraction of Antioxidant Compounds from Green Propolis Using Carbon Dioxide and Ethanol as Co-Solvent

“…The addition of a co-solvent in the supercritical carbon dioxide can significantly improve the extraction [ 89 ]. From the results shown on Table 2 , it can be demonstrated that the presence of the co-solvent on the SFE process increases the extraction capacity of the phenolic compounds, flavonoids and antioxidant activity (IC 50 ) of the green propolis under the conditions used.…”

“…The difference between the literature and the present work is, probably, due to differences in the extraction method and the characteristics of the raw material. Lin et al [ 89 ] identified that the quantity of extractable oil from Schisandra chinensis seeds are significantly increased with the presence of ethanol as co-solvent. The assumption is that the role of the co-solvent in the extraction is, mainly, to decrease the thickness of the limit layer for mass transfer, considering that the increase in the quantity of ethanol in the system does not significantly increase the process yield.…”

“…Piantino et al [ 103 ] identified the best global yield for leaves of Baccharis dracunculifolia at the higher temperature and pressure used (60°C and 400 bar), whereas the lowest global yield was obtained at lower conditions (40°C and 200 bar). Lin et al [ 89 ] determined the pressure of 350 bar and temperature of 50°C as the best conditions applied for the extraction of Schisandra chinensis seeds oil. Besides, they observed the same behaviour identified for the green propolis, that is, when the temperature increases from 40 to 50°C, with constant pressure of 350 bar, there is a significant increase in the extraction yield.…”

Advanced Operating Strategies to Extend the Applications of Simulated Moving Bed Chromatography

“…Since the first gradient application in conventional four-zone SMB chromatography was described [97], many different types of gradient operations have been proposed. These include SMB processes involving supercritical mobile phases [98][99][100][101][102][103][104][105], solvent composition modulations [24,25,[106][107][108][109][110][111][112][113][114][115], and temperature gradients [116]. In practice, not many gradient SMB processes are practically applied because of the difficulty in precisely controlling the travelling gradient profiles.…”

Extração de compostos bioativos de folhas de Vernonia amygdalina Delile utilizando dióxido de carbono em condições supercríticas

“…A condição 333 K e 13 MPa mostrou-se eficaz na extração dos compostos, que apresentaram atividade antifúngica (Cladosporium sphaerospermum ATCC 4464) e a 323 ou 333 K e 25 MPa, os extratos obtidos apresentaram atividade antibacteriana (Staphylococcus aureus ATCC25923). Um modelo matemático foi proposto a partir dos mecanismos de transferência de massas Lin et al (2015). estudaram a extração de lignanas proveniente da semente de Schisandra chinensis com fluido supercrítico e subsequente separação em leito móvel simulado utilizando fluido supercrítico.…”