Evaluation of the Antioxidant Activity ofSida cordifolia.

Abstract

Sida cordifolia Linn. (Malvaceae) is commonly known as bala and widely used in Ayurveda. The comparative antioxidant potential of ethanol extracts of Sida cordifolia leaf, stem, root, and whole plant was studied. Anti-lipid peroxidation, free-radical scavenging, reducing power, nitric oxide scavenging, superoxide scavenging antioxidant assay, and further estimation of total phenolic content and HPTLC studies were carried out. Various antioxidant activities were compared with standard antioxidants such as BHA, a-tocopherol, and ascorbic acid. Ethanol extracts were found to be a good scavenger of DPPH radical in the order roots > stem > leaves > whole plant with values 76.62%, 63.87%, 58% and 29% at a dose of 1 mg, respectively. All extracts of Sida cordifolia (SC) have effective reducing power and freeradical scavenging activity. Only the root extract exhibited superoxide-scavenging activity and inhibited lipid peroxidation in rat liver homogenate. All these antioxidant properties were concentration dependent. In addition, total phenolics content of all the extracts of S. cordifolia were determined as gallic acid equivalents. The highest antioxidant activity was observed in the root extract. The results obtained in the current study indicate that S. cordifolia is a potential source of natural antioxidants.

Evaluation of Antioxidant Activities by use of Various Extracts from Abutilon Pannosum and Grewia Tenax in the Kachchh Region

“…The results designate that methanolic fractions found from different solvent crude extract display higher antioxidant activities as associated to the only methanol solvent extract. This could be due to the fact that crude (methanol) extract tends to have more interfering substances as compared to fractions [45]. The results obtained of TAC that a DCE were shown higher absorption compare that of MFE but only methanol extract existed a very higher absorption capacity compare to other solvent extract in both plants.…”

Anti-Hyperglycemic, Anti-Hyperlipidemic and Antioxidant Potential of Alcoholic-Extract of Sida cordifolia (Areal Part) in Streptozotocin-Induced-Diabetes in Wistar-Rats

“…The reactive oxygen species (ROS) take electrons from polyunsaturated fatty acids of cell membrane which leads to LPO with the loss of cellular functions [63]. Dhalwal et al [20] reported that extracts from root of S. cordifolia scavenges the freeradical and possess antioxidant-activity. Auddy et al [64] also reported the in vivo and in vitro antioxidant activity of whole plant of S. cordifolia.…”

“…It is found through out the tropical and sub tropical plains of India. Its roots, leaves, stem and seeds are used in the folk medicine as anti-rheumatic [12], antipyretic [13], antiasthmatic [14], laxative, diuretic [12,15,16], vaso-relaxative [17], hypotensive [14], CNS depressant [18,19], antioxidant [20] and hypoglycemic effect [21,22]. Keeping the fact that diabetes is an emerging problem world-wide and is a major concern of developing countries like India; the present study was conducted with the aim to evaluate the anti-oxidative and anti-diabetic activity of S. cordifolia in streptozotocin (STZ) induced diabetes in wistar rats.…”

Preliminary Phytochemical Screening and in-Vitro Free Radical Scavenging Activity of Root Extracts of Glycyrrhiza Glabra L

“…They are currently under investigation by numerous groups for antitumor, antibiotic, anticancer, antineoplastic, antibacterial, anti-inflammatory, and other therapeutic properties [32]. Terpenoids are the most widespread, chemically interesting groups of secondary metabolites with over 30,000 known compounds [33,34]. Many terpenes have biological activities and are used for the treatment of human diseases.…”