Evaluation of free radical scavenging activity of various extracts of leaves from Kedrostis foetidissima (Jacq.) Cogn.

Kalaisezhiyen, Pavithra; Vadivukkarasi, S.

doi:10.1016/j.fshw.2015.02.001

Cited by 222 publications

(131 citation statements)

References 10 publications

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“…24 FRAP assay depends upon the ferric tripyridyltriazine (Fe (III)-TPTZ) complex to the ferrous tripyridyltriazine (Fe (II)-TPTZ) by a reductant at low pH. Fe (II) -TPTZ has an intensive blue color and can be monitored at 593 nm.…”

Section: Ferric Reducing Antioxidant Power (Farp) Assaymentioning

confidence: 99%

In vitro Anti-oxidant Activity in Methanolic Extracts of five Pogostemon Spciece

Kaliyappan¹,

Nallasamy²,

Thirumuruthy³

2017

FRA

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A multifaceted peer reviewed journal in the field of Free Radicals and Antioxidants www.antiox.org | www.phcog.net Original Article INTRODUCTIONPlants have provided with all in terms of shelter, clothing, food, flavours and fragrances and medicine properties. Plants have formed the basis of complicated traditional medicine systems that have been in continuation for thousands of years to provide new remedies. The Lamiaceae contains about 236 genera and 6,900 to 7,200 species, 1 in this Pogostemon is one of the important genera and a large widespread genus having 114 species in India. Both roots and leaves are mostly used by tribal people in this genus like the fresh root or poultice of the leaves is applied on the snake bites particularly Phursa (Echis carinatus) snake bite, uterine haemorrhage, leaf extract used as an insect repellent, treatment of food poison, vomiting and stomach troubles, respiratory tract infection and pollen and nectar used as a source of Panagol honey in Maharashtra. The superoxide anion (O 2 ) hydrogen peroxide (H 2 O 2 ) and hydroxyl radical (OH) are the form of active oxygen and free radicals. These are constantly formed in human body through normal metabolic action. Hence, this leads to a variety of biochemical and physiological lesion, often consequent in metabolic destruction and cell death. 3 The synthetic antioxidants were creating the genotoxic effect 4 and other chronic disease.5 Therefore, the antioxidant properties of secondary metabolites have formed the foundation of many applications in a preservation process as pharmaceuticals, alternative medicine and natural therapies. Here the studies to explore the five Pogostemon species which have been scientific conform for their potential medicinal values. MATERIALS AND METHODS Preparation of plant extractsPogostemon vestitus, P. mollis, P. speciosus, P. wightii and P. nilagiricus were colocted belongs to the family Lamiaceae were collected from natural forest of Western Ghats of Coimbatore, Tamil Nadu. The specimen was identified by Dr. M. Murugesan, Scientist B, Botanical Survey of India, Shillong. Fresh plant materials were washed under running tap water, air-dried and powdered. About 50 g of coarsely powdered plant materials (50 g/250 ml) were extracted in a soxhlet extractor for 8-10 hrs, with methanol. The extract obtained was then concentrated using a vacuum evaporator and weighted. For stock solutions, 1 mg/ml of methanolic extract was dissolved in dimethyl sulfoxide (DMSO). Determination of Total phenolsTotal phenolics were quantified and expressed as Gallic acid equivalents according to a method proposed by Singleton et al. 7 About 3.9 ml of distilled water and 0.5 mL of Folin-ciocalteau reagent were added to 0.1ml of the extract in a tube and incubated at room temperature for 3 min after which 2 mL of 20% sodium carbonate was added and kept in a boiling water bath for 1 min. Phenols react with phosphomolybdic acid in the Folin-ciocalteau reagent in alkaline medium and produce a blue coloured complex (molybdenum blue) th...

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Section: Ferric Reducing Antioxidant Power (Farp) Assaymentioning

confidence: 99%

In vitro Anti-oxidant Activity in Methanolic Extracts of five Pogostemon Spciece

Kaliyappan¹,

Nallasamy²,

Thirumuruthy³

2017

FRA

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“…Phenolic compounds (phenols, flavonoids and proanthocyanidins) received considerable attention because of their potential anti-oxidant activity (Suhartonoa et al, 2012;Pavithra and Vadivukkarasi, 2015;Khlif et al, 2015;John and Shahidi, 2010). These compounds are known for their ability of scavenging free radicals and active oxygen species such as single oxygen (Lahlou et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

“…DPPH gives a strong absorption band at 517 nm in visible spectroscopy. The stable free radical DPPH has been widely used to test the free radical-scavenging capacity of various antioxidants (Pavithra and Vadivukkarasi, 2015). If the extracts have the capacity to scavenge the DPPH free radical, the initial purple solution will change to a yellow color due to the formation of diphenylpicrylhdrazine.…”

Section: Discussionmentioning

confidence: 99%

Anti-oxidant and anti-acetylcholinesterase activities of Zygophyllum album

Kchaou

Salah

Mhiri

et al. 2015

Bangladesh J Pharmacol

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The present study was carried out to explore the anti-acetylcholinesterase activity and anti-oxidant effect as well as content of phenolic compounds of various extracts from Zygophyllum album. It was observed that dichloromethane and ethanol extracts were endowed with a powerful anti-acetylcholinesterase activity with IC50 values of 40 and 58 µg/mL, respectively. These two extracts exhibited the highest DPPH radical scavenging activity (IC50=0.2 mg/mL), the highest total anti-oxidant capacity (185.2 and 222.4 mg vitamin E/mg extract, respectively), the highest reducing power effect, and the highest β-carotene bleaching capacity. The findings showed that the extents of anti-acetylcholinesterase activity of Z. album extracts as well as their anti-oxidant capacity are in accordance with their phenolic contents. Hence, Z. album leaves would be useful against Alzheimer's disease. VIDEO CLIP<a href="https://www.youtube.com/v/M03zi4Mzh6k">Determination of flavonoids content:</a> 2 min 50 sec

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“…After cooling to room temperature the absorbance was measured at 695nm against blank. Ascorbic acid was used as the standard and the total antioxidant capacity is expressed as equivalents of Ascorbic acid 18 .…”

Section: Phosphomolybdenum Assay (Total Antioxidant Capacity)mentioning

confidence: 99%

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2018

IJPSR

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Persimmon (Diospyros kaki Linn.), which belongs to the Ebenaceae family, have numerous bioactive compounds such as polyphenols, dietary fiber, carotenoids and minerals. This fruit possesses hypolipidemic and antioxidant properties and can be used in antiatherosclerosis diets. The present paper reveals the phytochemical screening, Antioxidant, Anti-inflammatory activity and GC-MS Spectral analysis of the isolated fatty acids compounds of the plant Diospyros kaki. From the Antioxidant and Anti-inflammatory activity the chloroform fraction of ethanolic extract showed the good activity and proceeded for isolation. Six fatty acid compounds were isolated from the plant Diospyros kaki and analyzed using Gas chromatography-Mass Spectrometry. From the analysis 13 compounds were identified by comparing their retention time and peak area with that of literature and interpretation of mass spectra. The major phytoconstituents were Spiro [(tricyclo [6.2.2.0(2, 7)] dodeca and 1-monolinoleoylglycerol trimethylsilyl ether. Hence this study creates a platform to screen many bioactive components to treat many diseases.

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Evaluation of free radical scavenging activity of various extracts of leaves from Kedrostis foetidissima (Jacq.) Cogn.

Cited by 222 publications

References 10 publications

In vitro Anti-oxidant Activity in Methanolic Extracts of five Pogostemon Spciece

In vitro Anti-oxidant Activity in Methanolic Extracts of five Pogostemon Spciece

Anti-oxidant and anti-acetylcholinesterase activities of <i>Zygophyllum album</i>

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