Evaluation of a new single-piece 4% water content hydrophobic acrylic intraocular lens in the rabbit model

Abstract

In this rabbit study, the new hydrophobic acrylic material was biocompatible. The barrier step incorporated to the optic-haptic junctions has the potential to enhance PCO prevention.

Evaluation of stability and capsular bag opacification of a new foldable adjustable intraocular lens

“…Anaesthesia, surgical preparation and bilateral phacoemulsification with IOL implantation were performed as described in previous studies . Briefly, using aseptic technique and a surgical microscope, a fornix‐based conjunctival flap was fashioned.…”

“…Gross examination and photographs from the posterior aspect (Miyake–Apple view) were performed to assess capsular bag opacification and IOL fixation. The extent and severity of anterior capsule opacification (ACO) and PCO were scored according to previously described methods …”

“…Anaesthesia, surgical preparation and bilateral phacoemulsification with IOL implantation were performed as described in previous studies. [4][5][6][7] Briefly, using aseptic technique and a surgical microscope, a fornix-based conjunctival flap was fashioned. A corneal-scleral incision was then made, and the anterior chamber was entered with a 3.0-mm keratome, followed by injection of an ophthalmic viscosurgical device (AmVisc Plus, Bausch & Lomb, Rochester, New York, USA).…”

New Hydrophobic IOL Materials and Understanding the Science of Glistenings

“…It was observed that PCO was significantly less in the enVista lenses, which had a PCO score of 1.5 ± 1.0 compared to the AcrySof with a score of 2.2 ± 1.09 and that the lenses were otherwise equally biocompatible. 90 These results and the promising accounts of early experiences from ophthalmologists make the latest generation of hydrophobic lenses with a water dispersing component an attractive option. This may be the beginning of a new group of hydrophobic IOLs with water contents around 4-5% offering measurable material advantages.…”

An Introduction to Intraocular Lenses: Material, Optics, Haptics, Design and Aberration

“…To overcome this drawback, new materials have been introduced that are prehydrated to equilibrium and will not accept further water, thus avoiding the formation of glistenings. These IOLs are hydrophobic because the contact angle with water is that of hydrophobic acrylic, but are packaged in BSS to absorb the eventual 4% water content before implantation [16].…”