Essential oil analysis and antimicrobial activity of eight Stachys species from Greece

Skaltsa, Helen; Demetzos, Costas; Lazari, Diamanto; Sokóvić, Marina

doi:10.1016/s0031-9422(03)00386-8

Cited by 226 publications

(117 citation statements)

References 20 publications

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“…Although ulcer etiology is unknown in most cases, it is generally accepted that an imbalance between acid and pepsin production and mucosal integrity would be causative factor acting via endogenous defense mechanisms (Wallace and Granger, 1996). Hence, it is right to state here that S. lavandulifolia extract, which is acted as a therapeutic agent for anti-inflammatory and antibacterial, and wound healing activity (Maleki et al, 2001;Khanavi et al, 2005;Skaltsa et al, 1999;Skaltsa et al, 2003;GhasemiPirbalouti, 2011), has an anti-ulcer potential. Further work for its specific anti-ulcer mechanism is in progress.…”

Section: Discussionmentioning

confidence: 99%

“…Boiled extract obtained from the aerial parts of S. lavandulifolia are used as antipyretic, anti-inflammatory, spasmolytic and sedative medicament (Naghibi et al, 2005). Anti-inflammatory and antibacterial effects, and wound healing activity of S. lavandulifolia extract have been shown in several pharmacological studies (Maleki et al, 2001;Khanavi et al, 2005;Skaltsa et al, 1999;Skaltsa et al, 2003;Ghasemi-Pirbalouti, 2011). Since gastric acid and pepsin are involved in gastric ulcer pathology and there is no academic study on S. lavandulifolia extract effect on this issue, we conducted the present investigation to elucidate therapeutic and preventive effects of S. lavandulifolia extract on gastric acid-pepsin secretions together with NO's possible role.…”

Section: Introductionmentioning

confidence: 95%

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Gastroprotective effects of Stachys Lavandulifolia extract on experimental gastric ulcer

Nabavizadeh¹

2011

Afr. J. Pharm. Pharmacol.

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Several studies have used Stachys Lavandulifolia vahl (S. lavandulifolia) as medicinal plant in Iranian folk medicine. The present investigation is designed to elucidate therapeutic and preventive effects of S. lavandulifolia extract on gastric acid and pepsin secretions in experimental gastric ulcer. Thirty two Wistar male rats were used to study therapeutic and preventive effects of S. lavandulifolia extract on alcohol-induced gastric ulcer. Animals were equally (n=8) divided into 4 groups: (I) Control (II) Alcohol (1 ml/200 g/bw) to induce gastric ulcer (III) Alcohol/Lvandu (100 mg/kg bw/daily, S. lavandulifolia extract was given for two weeks post alcohol administration) and (IV) Lvandu/alcohol (S. lavandulifolia extract was given for two weeks before alcohol administration). Ulcer index, gastric acid and pepsin secretions was measured. Ulcer index was significantly decreased in alcohol/Lvandu than Alcohol group. Also gastric acid and pepsin secretions, and gastric tissue's NO metabolites level were significantly lower in alcohol and Lvandu/alcohol groups than control (p<0/05). But changes in gastric acid and pepsin secretions have not been noticeable in alcohol/Lvandu group than control. The results of this study show that S. lavandulifolia extract protected gastric mucosa from alcohol-induced gastric ulcer. This gastroprotection may mediate via gastric mucosal nitric oxide production.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 95%

Gastroprotective effects of Stachys Lavandulifolia extract on experimental gastric ulcer

Nabavizadeh¹

2011

Afr. J. Pharm. Pharmacol.

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“…Numerous studies have been published on the antimicrobial activities of plant compounds against many different types of microbes, including food-borne pathogens (Friedman et al, 2002). The most antibacterial effects of the essences and their components refer to hydrophobia traits in the essential oils which are caused to infiltrate the lipidic walls of bacterial cells and can be changed its structures (Skaltsa et al, 2003) and consequently many ions and cellular substrates percolate toward to outside of cells and be ultimately dying of bacteria (Carson et al, 2002). The antifungal and antibacterial activity exhibited by the extracts and essential oils of medicinal plants has been demonstrated by several researchers (Ghasemi Pirbalouti et al, 2009;Ghasemi Pirbalouti et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Chemical composition and antimicrobial activity of essential oil of Salvia officinalis L. and Salvia virgata Jacq

et al. 2017

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Background & Aim: The genus Salvia (commonly known as sage) is a broad genus belonging to the family Lamiaceae. This study is aimed at assessing the essential oil composition and antimicrobial activities of two Salvia species. Experimental:The chemical composition of the essential oils of Salvia officinalis L. and Salvia virgata Jacq, cultivated in Estahban (Fars, South Iran), was studied by means of GC-MS analyses. Antimicrobial activity was tested against a panel of microorganisms including one Gram-positive (Staphylococcus epidermidis PTCC NO. 1435) and one Gram-negative (Escherichia coli) and three fungal strain (Alternaria alternata PTCC NO. 5224, Penicillium funiculosum PTCC NO. 5301 and P. funiculosum PTCC NO. 5169) using the disk diffusion and agar-well diffusion methods and the Minimum Inhibitory Concentration (MIC) technique. Results:In all, 57 compounds were identified, 42 for S. officinalis, accounting for 98.94% of the total oil, 29 for S. virgata (98.81%). The major components of S. officinalis essential oil were α-thujone (37.18%), 1,8-cineole (12.71%), β-thujone (9.10%) and the major components of S. virgata essential oil were caryophyllene oxide (30.23%), β-caryophyllene (22.63%), sabinene (11.82%). The antimicrobial activity of the total essential oil evaluated by the agar-well diffusion method, the results showed that the highest active against S. epidermidis and also the least active against E. coli. Inhibition of growth was tested by the disk diffusion method, the results showed that essential oil of S. officinalis and S. virgata were highest active against E. coli and P. funiculosum (PTCC NO. 5301), respectively. Also the least active against A. alternata. Recommended applications/industries:The results showed that S. officinalis oil had higher antimicrobial activity compare to S. virgata.

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“…A lot of fatty acids exhibit antibacterial and antifungal activity (Dilika et al 2000) among other hexadecanoic acid (palmitic acid) (McGraw et al 2002) (Azcan et al 2004;Skaltsa et al 2003). One of the most interesting properties of palmitic acid is the supposed inhibition of HIV-1 infection (Paskaleva et al 2010).…”

Section: Resultsmentioning

confidence: 99%

Comparative study on the essential oils of Myosotis arvensis and Myosotis palustris herbs (Boraginaceae)

et al. 2014

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The essential oils were obtained from Myosotis arvensis L. and M. palustris L. by hydrodistillation and subsequently analyzed by GC-MS. Fifteen components in M. arvensis and twenty-one in M. palustris representing, respectively, 89.63 and 93.19 % of the total oils were identified on the basis of their retention time, mass spectra characteristics and semi-quantitative data were obtained from relative peak area percentages. The 3-methyl-benzaldehyde was found to be the major constituent of both tested oils (42.76 % in M. arvensis and 45.80 % in M. palustris). Additionally, methyl salicylate was a characteristic compound for M. arvensis and a-bisabolol oxide B for M. palustris.

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Essential oil analysis and antimicrobial activity of eight Stachys species from Greece

Cited by 226 publications

References 20 publications

Gastroprotective effects of Stachys Lavandulifolia extract on experimental gastric ulcer

Gastroprotective effects of Stachys Lavandulifolia extract on experimental gastric ulcer

Chemical composition and antimicrobial activity of essential oil of Salvia officinalis L. and Salvia virgata Jacq

Comparative study on the essential oils of Myosotis arvensis and Myosotis palustris herbs (Boraginaceae)

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