Errors in the clinical assessment of periodontal destruction

Glavind, Leif; Löe, Harald

doi:10.1111/j.1600-0765.1967.tb01887.x

Cited by 354 publications

(213 citation statements)

References 7 publications

Supporting

Mentioning

194

Contrasting

Unclassified

Order By: Relevance

“…The patients were categorized as having healthy periodontium or chronic generalised periodontitis based on bleeding on probing, gingival index (GI) 18) , pocket depth (PD), and clinical attachment level (CAL) 13) scores together with radiograph evidence of bone loss. A GI score of 0, PD≤3 mm, CAL=0, and no evidence of bone loss on a radiograph was considered to indicate a healthy periodontium.…”

Section: Selection Criteriamentioning

confidence: 99%

Interleukin-34 Levels in Gingival Crevicular Fluid and Plasma in Healthy and Diseased Periodontal Tissue in Presence or Absence of Obesity: A Clinico-biochemical Study

Guruprasad

Pradeep

2018

Bull. Tokyo Dent. Coll.

View full text Add to dashboard Cite

Interleukin (IL)-34 has recently been identified as an alternative ligand for colonystimulating factor-1 receptor and plays an important role in osteoclastogenesis. The aim of this study was to assess and compare IL-34 levels in gingival crevicular fluid (GCF) and plasma in obese individuals in the presence or absence of periodontal disease and to determine whether they showed a correlation with disease severity. Forty patients aged between 25 and 40 yr were enrolled and categorized into 4 groups: 10 non-obese patients with healthy periodontium (Group I); 10 obese patients with healthy periodontium (Group II); 10 non-obese patients with chronic periodontitis (Group III); and 10 obese patients with chronic periodontitis (Group IV). Demographic variables such as age and body mass index score were recorded and assessed, together with clinical periodontal parameters such as the gingival index, probing pocket depth, and clinical attachment level scores in all groups. The GCF and plasma levels of IL-34 were quantified using enzyme-linked immunosorbent assay. The results showed that the mean IL-34 concentrations in GCF or plasma were highest in Group IV, followed by Group III, Group II, and Group I, with the difference among them being statistically significant (p<0.05). These results suggest that obese individuals with periodontitis have higher GCF and plasma IL-34 levels than non-obese individuals with healthy periodontium. This suggests IL-34 as a potential inflammatory marker of periodontal disease and obesity.

show abstract

Section: Selection Criteriamentioning

confidence: 99%

Interleukin-34 Levels in Gingival Crevicular Fluid and Plasma in Healthy and Diseased Periodontal Tissue in Presence or Absence of Obesity: A Clinico-biochemical Study

Guruprasad

Pradeep

2018

Bull. Tokyo Dent. Coll.

View full text Add to dashboard Cite

show abstract

“…For each patient, the following clinical parameters were recorded on 6 points per tooth mesio-mid and distobuccal, mesio-mid and disto-lingual: (1) Periodontal probing depth (PD) as described by Glavind & Löe (1967 (Löe & Silness, 1963;Silness & Löe, 1964). The scores from 0 to 3 are as follows: Score 0 ¼ Gingival areas of tooth free from plaque, Score 1 ¼ No plaque was observed in-situ by the unaided eye, but plaque is made visible on the tip of a probe after it has been moved over the tooth surface at the entrance of the gingival crevice, Score 2 ¼ Gingival area covered by a thin to moderately thick layer of plaque visible to the naked eye.…”

Section: Clinical Variables Studiedmentioning

confidence: 99%

Formulation, in-vitro characterization and clinical evaluation of curcumin in-situ gel for treatment of periodontitis

et al. 2017

View full text Add to dashboard Cite

This study aimed to develop syringeable in-situ curcumin (cur) gel for the treatment of periodontal pockets as well as to evaluate the clinical efficacy of Cur in-situ gel formulation. Different in-situ gel formulations of Cur were prepared using 30% of pluronic F127, and 1% of carbopol P934. The formulations were evaluated regarding gelation temperature, pH, viscosity, syringeability study, in-vitro release and chemical stability of cur. The effect of aging of gel formulations for 3months in refrigerator was investigated. The selected formulation was clinically evaluated through the determination of probing depth, plaque index, and bleeding index at baseline and 1 month after application. The formulations showed accepted gelation temperature ranging from 28 to 34 C and all had pH value of 4. The viscosity of the formulations at 4 C ranged from 19 000 to 37 000 cP. All formulations were easily syringeable through 21 gauge needle at cold temperature. Curcumin stability during the release study was maintained. Aging showed no significant effect on release profile, drug content, or the pH after 3 months, while it showed a slight increase in viscosity with concomitant decrease in gelation temperature. Selected formulations delivered into periodontal pocket evaluated clinically showed to be effective. The treated group revealed that the adjunctive use of intracrevicular 2% curcumin in-situ gel adjunct to mechanical treatment in patients with adult periodontitis could aid in significant clinical reduction of probing depth, bleeding index, and to less extent of plaque. This indicates that curcumin in this novel drug delivery system is an excellent candidate for periodontal disease treatment.

show abstract

“…Subjects in the age group of 25-45 years; presence of at least 20 natural teeth, subjects with a diagnosis of CP based on clinical parameters like probing depth (PD), clinical attachment level (CAL) [28], gingival index (GI) [29]; subjects having BMI, in non obese subjects in the range of 18.5 22.9 kg/m 2 and in obese subjects 25 kg/m 2 and waist circumference (WC) 90 cm in men and 80 cm in women [30], were selected in this study. Radiographic bone loss was recorded dichotomously (presence or absence) to differentiate subjects with CP from other groups.…”

Section: Inclusion Criteriamentioning

confidence: 99%

Association of Progranulin and High Sensitivity CRP Concentrations in Gingival Crevicular Fluid and Serum in Chronic Periodontitis Subjects with and without Obesity

et al. 2012

View full text Add to dashboard Cite

Background: Obesity is considered as a strong risk factor of inflammatory periodontal tissue destruction. The purpose of this study is to determine presence of progranulin (PGRN) and high sensitivity C reactive protein (hs CRP) levels in serum and gingival crevicular fluid (GCF) in obese subjects with chronic periodontitis and to find an association, if any.Material and methods: 40 subjects (20 males and 20 females) were selected based on their clinical parameters into four groups (10 subjects in each group): group 1 (healthy non obese), group 2 (healthy obese), group 3 (non obese with chronic periodontitis) and group 4 (obese with chronic periodontitis). Serum and GCF PGRN levels were estimated by enzyme linked immunosorbant assay (ELISA) and hs CRP levels were estimated by immunoturbidimetry method.Results: The mean PGRN and hs CRP concentration both in serum and GCF were highest for group 4 followed by group 3, group 2 and least in Group 1.Conclusion: PGRN and hs CRP may be novel biomarkers of the chronic inflammatory response in obesity and chronic periodontitis.

show abstract

Errors in the clinical assessment of periodontal destruction

Cited by 354 publications

References 7 publications

Interleukin-34 Levels in Gingival Crevicular Fluid and Plasma in Healthy and Diseased Periodontal Tissue in Presence or Absence of Obesity: A Clinico-biochemical Study

Interleukin-34 Levels in Gingival Crevicular Fluid and Plasma in Healthy and Diseased Periodontal Tissue in Presence or Absence of Obesity: A Clinico-biochemical Study

Formulation, in-vitro characterization and clinical evaluation of curcumin in-situ gel for treatment of periodontitis

Association of Progranulin and High Sensitivity CRP Concentrations in Gingival Crevicular Fluid and Serum in Chronic Periodontitis Subjects with and without Obesity

Contact Info

Product

Resources

About